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The core cerebrospinal fluid (CSF) Alzheimer's disease (AD) biomarkers amyloid beta (Aβ42 and Aβ40), total tau, and phosphorylated tau, have been extensively clinically validated, with very high diagnostic performance for AD, including the early phases of the disease. However, between-center differences in pre-analytical procedures may contribute to variability in measurements across laboratories.
OBJECTIVES: Under physiological conditions the blood flow velocity waveform in the umbilical vein (UV) has an even non-pulsating pattern. Pulsations in the UV have been described in human fetuses exposed to chronic hypoxia and heart failure. Current techniques for fetal surveillance during labor and delivery involve a risk of both over- and underestimation of fetal hypoxia. We aimed to examine whe
Epidemiological studies have shown a high prevalence of mental illness among the elderly. Clinical data however indicate both insufficient detection and treatment of illnesses. Suggested barriers to treatment include conceptions that mental health symptoms belong to normal aging and lack of competence among staff in elderly care in detecting mental illness. A Mental Health First Aid (MHFA) trainin
Climate policy is a relatively young and dynamic area of public policy making. However, its development has attracted far more attention than the results it delivers in practice, which of course are the concern of policy evaluators. This article attempts to provide the first systematic cataloging of the emerging patterns of policy evaluation undertaken in different parts of the European Union. The
The Special Criminal Court in the Central African Republic becomes the first hybrid or internationalised criminal tribunal to be created since the coming into existence of the International Criminal Court in 2002. Born out of the realisation that the Central African Republic was a phantom State without a properly functioning national criminal justice system with no capacity to bring justice and ac
Bioenergy with Carbon Capture and Storage (BECCS) is a largely promoted, but also heavily contested solution to the problem of climate change. Whilst removing carbon from the atmosphere, it potentially leads to detrimental side effects. This thesis provides guidance for NGOs, industry and policymakers in Germany and the wider EU context on how to assess the sustainability of BECCS implementation p
Problemformulering: Med sociala mediers stigande popularitet har influencer marketing blivit en relevant strategi för företag att utnyttja. Influencer marketing på Instagram innebär att varumärken använder sig av influencers för att kommunicera budskap till följare och därmed företagets målgrupp. Beroende på hur företag använder sig av sin influencer marketing-strategi kan konsumenters förtroende
Watershed projects are one example of a decentralization trend, where the entire community is supposed to be involved in planning and implementation. Watershed projects are often considered a success for the environment treated, and often lead to an increased income for those living in the watershed areas. The specific aim of this thesis is to study the potential gender-specific direct and indirec
Payments for watershed services (PWS) are intended to provide incentives to land users to adopt sustainable land management practices. They are also increasingly viewed as having positive impacts on the livelihood of local communities around protected areas. The St. Paul River, located in the St. Paul River basin, is the main source of potable water and hydroelectricity to Monrovia, a city with ab
Sustainability, population dynamics and health issues are some of the greater challenges the global society faces today. Meat consumption has emerged as one of the reasons behind the cause and effect of these challenges. There is a growing consensus amongst researchers, industry stakeholders and decision-makers that there is a need to transition into more sustainable alternatives to meat. As a res
Den additiva tillverkningsprocessen och kvalificeringen av komponenter i metall är komplex och tillverkningsmetoden är inte ännu fullständigt förstådd. Syftet med detta examensarbete är därför att förvärva kunskap om kvalificeringsprocesser kopplade till additiv tillverkning i metall och att utveckla en hållbar kvalificering för additivt tillverkade komponenter hos Alfa Laval. KvalificeringsprocedThe process of additive manufacturing and qualification of components in metal is complex, and the manufacturing method is still not fully understood. Therefore, the purpose of this thesis is to gather knowledge of the qualification procedures connected to additive manufacturing in metal and to develop sustainable qualification for additively manufactured parts at Alfa Laval. The qualification pro
The introduction of new farming technologies, such as high-yielding varieties, has for long been regarded as one of the best strategies to increase agricultural production, and to combat poverty and food-insecurity. Since around 2005, New Rice for Africa (Nerica) is one of the main development strategies for combating such issues in Sierra Leone, and in many other African countries. Africa Rice Ce
OBJECTIVES: Sport-related concussions are an increasingly recognized health problem. Soccer is the most popular sport in the world although recent studies on concussion incidence are scarce. Here, a nation-wide prospective study on concussion incidence, symptom severity, risk factors, gender differences and return-to-play after concussion was performed in 51 Swedish elite soccer teams during the 2
Europe is struggling to reduce its CO2 emissions and to fulfil commitments made according to Kyoto protocol. At the same time, Europe does not possess enough fossil energy resources to cover its needs and thus consumption of imported fossil fuels is growing, placing threats upon economic stability. In order to combat these challenges, renewable energy sources and biomass in particular are expected
Using biomass for charcoal production in sub-Saharan Africa (SSA) may change carbon stock dynamics and lead to irreversible changes in the carbon balance, yet we have little understanding of whether these dynamics vary by biome in this region. Currently, charcoal production contributes up to 7% of yearly deforestation in tropical regions, with carbon emissions corresponding to 71.2 million tonnes
Der p 2 is one of the most important allergens from the house dust mite Dermatophagoides pteronyssinus Identification of human IgE Ab binding epitopes can be used for rational design of allergens with reduced IgE reactivity for therapy. Antigenic analysis of Der p 2 was performed by site-directed mutagenesis based on the x-ray crystal structure of the allergen in complex with a Fab from the murine
The R¨onneholm-Ager¨od peatland complex, situated in central Scania, contains numerous archaeological sitesdiscovered since the 19th century. Two sediment sequences were obtained at the Ager¨od peatland to compare thesediment stratigraphy with a previous sequence obtained in 1960 to detect any modern-day changes and toestablish the Holocene environmental development in the area. To clarify the tim
Independent estimation and verification of fossil CO2 emissions on a regional and national scale are crucial for evaluating the fossil CO2 emissions and reductions reported by countries as part of their nationally determined contributions (NDCs). Top-down methods, such as the assimilation of in situ and satellite observations of different tracers (e.g., CO2, CO, Δ14CO2, XCO2), have been increasing
Objective: To develop a reliable and valid short form of the State Anxiety Subscale of the State-Trait Anxiety Inventory for Children (STAI-CH) in the Environmental Determinants of Diabetes in the Young (TEDDY) study. Methods: A Development Sample of 842 10-year-old TEDDY children completed the STAI-CH State Subscale about their type 1 diabetes (T1D) risk. The best 6 items (three anxiety-present a
