Search results

In the research on two of the most prominent persons among those who rescued Jews from the Holocaust, Oskar Schindler and Raoul Wallenberg, a reappearing purpose has been to separate mythical, and therefore more or less false, elements in the story from the true, and implicit, academic historical writing. However, during the last decades, it has been obvious that history is not only, and sometimes

Animal venoms and toxins are a valuable source of bioactive peptides with pharmacologic relevance as potential drug leads. A large subset of biologically active peptides discovered up till now contain disulfide bridges that enhance stability and activity. To discover new members of this class of peptides, we developed a workflow screening specifically for those peptides that contain inter- and int

BACKGROUND: Mean diffusivity (MD) and fractional anisotropy (FA) from diffusion MRI (dMRI) have been associated with cell density and tissue anisotropy across tumors, but it is unknown whether these associations persist at the microscopic level.PURPOSE: To quantify the degree to which cell density and anisotropy, as determined from histology, account for the intra-tumor variability of MD and FA in

Common single-nucleotide polymorphisms (SNPs) are predicted to collectively explain 40–50% of phenotypic variation in human height, but identifying the specific variants and associated regions requires huge sample sizes1. Here, using data from a genome-wide association study of 5.4 million individuals of diverse ancestries, we show that 12,111 independent SNPs that are significantly associated wit

Background: About two-thirds of patients with Alzheimer’s disease (AD) are women, mostly because of their longer life-span and the higher prevalence of AD among older persons. A more-pronounced association between AD pathology and dementia (faster brain atrophy) and more-rapid cognitive decline have been reported in women. The AD prognosis might be affected by, e.g., size of cerebral hemispheres,

Studies on cultural evolution from archaeology, neuroscience and cognitive semiotics have shown the role of tool making for development of novel cognitive capabilities in early humans. Therefore, it is reasonable to assume that tool making was a cognitive threshold from nonhuman primates to hominins. Tool making begun with rudimentary skills for tool production based on motor patterns, learned soc

Malafouris (2013) proposes that agency is an emergent product of the relational ontology of our material engagement. However, I suggest a distinction between meaning and agency for a better understanding of our relational ontology with things. Meaning is the payoff of the relational ontology, meaning emerges when an agent act within the world. Agency is the capability to act, signify, produce and

The performance of HVAC equipment, including chillers, is continuing to be pushed to theoretical limits, which impacts the necessity for advanced control logic to operate them efficiently and robustly. At the same time, their architectures are becoming more complex; many systems have multiple compressors, expansion devices, evaporators, circuits, or other elements that challenge control design and

The physician’s communication skill influences the patient’s mental and physical wellbeing, as well as the physician’s own experience of stress. Most patients wish to be informed about their disease, by physicians who are honest, gives time, sustains hope, listens and shows compassion and empathy. Even though there are established guidelines on how to break bad news, the physician must find out an