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OBJECTIVE: To explore the cerebrospinal fluid (CSF) proteome in systemic lupus erythematosus (SLE) and the associations between the CSF proteomic patterns and clinical manifestations.METHODS: CSF samples from 29 female outpatients with SLE were analyzed with label-free liquid chromatography tandem mass spectrometry. Inclusion and CSF collection were conducted irrespective of clinical manifestation

This essay investigates the need for prioritizing resilience and mindfulness in academia and elaborated on a pragmatic approach to how we as scholars can improve our well-being collectively in today’s demanding academic environment.

Metal-assisted chemical etching (MACE) is a cheap and scalable method that is commonly used to obtain silicon nano- or microwires but lacks spatial control. Herein, we present a synthesis method for producing vertical and highly periodic silicon microwires, using displacement Talbot lithography before wet etching with MACE. The functionalized periodic silicon microwires show 65% higher PEC perform

Air pollution in urban environments exhibits large spatial and temporal variations due to high heterogeneous air flow and emissions. To address the complexity of local air pollutant dynamics, a comprehensive large-eddy simulation using the PALM model system v6.0 was conducted. The distribution of flow and vehicle emitted aerosol particles in a realistic urban environment in Malmö, Sweden, was stud

Cardiovascular magnetic resonance (CMR) can accurately measure left ventricular (LV) mass, and several measures related to LV wall thickness exist. We hypothesized that prognosis can be used to select an optimal measure of wall thickness for characterizing LV hypertrophy. Subjects having undergone CMR were studied (cardiac patients, n = 2543; healthy volunteers, n = 100). A new measure, global wal

EU:s art- och habitatdirektiv listar arter och naturtyper som ska bevaras och vars bevarandestatus ska övervakas. Rapporten analyserar förekomsten i Sverige av fyra av de fjärilsarter som omfattas av Naturvårdsverkets Biogeografiska uppföljning. Analysen fokuserar på habitat och miljöparameterar i relation till svenska fynd av högnordisk blåvinge (Agriades aquilo), dvärgpärlemorfjäril (Boloria imp

There have been previous studies comparing experimental methods for the purpose of capturing gaseous yields at a range of global equivalence ratios. However, no work has investigated the capability of the open controlled atmosphere cone calorimeter for collecting such data where its two modes of operation are directly compared. The aim of this study is to compare carbon monoxide yields collected u

Purpose: Although persistent offenders with histories of imprisonment and violence have disproportionate high rates of psychiatric disorders, little is known of their psychiatric healthcare utilization (HCU) and HCU-associated factors. This study aimed to explore psychiatric HCU, psychiatric morbidity, and psychotropic prescription drugs in violent offenders with a history of incarceration. Method

The LHCb system requires high efficiency muon detection into LHC bunch crossing: 95% into a 25 ns time window. To reach such efficiency many parameters of the detector readout apparatus have to be calibrated and adjusted and its channels must be aligned in time. In addition, essential characteristics must be monitored to guarantee a good working condition of the apparatus (to avoid loss of efficie

Shrunken pore syndrome (SPS) is defined by a cystatin C-based estimation of glomerular filtration rate (eGFRCYS) being less than 60% or 70% of a creatinine-based GFR estimation (eGFRCR) in the absence of extrarenal influences on cystatin C or creatinine concentrations. SPS has been associated with a substantial increase in mortality or morbidity in all investigated populations. However, in these s

The extent and composition of the immune response in a breast cancer is one important prognostic factor for the disease. The aim of the current work was to refine the analysis of the humoral component of an immune response in breast tumors by quantifying mRNA expression of different immunoglobulin classes and study their association with prognosis. We used RNA-Seq data from two local population-ba

Världens städer växer i snabb takt. Denna avhandling undersöker välbefinnandet och sårbarheten hos befolkningen i stadsnära, eller periurbana, låginkomstområden i och runt Bogotá, Colombia, med målet att öka förståelsen för hur sociala och miljömässiga förutsättningar påverkas av stadsutbredning och förtätning.För detta syfte har jag utvecklat en typologi för periurbana bosättningar som består av The world is rapidly urbanizing. To contribute to the understanding of the socio-environmental changes brought about by urban sprawl and densification, this thesis examines wellbeing and vulnerability in low-income peri-urban areas in and around Bogotá, Colombia. For that purpose, I develop a typology of peri-urban settlements that includes four main settlement classifications: agriculture-based,