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Popular Abstract in Swedish Genetisk påverkan i ledgångsreumatism Ett väl fungerande immunsystem är en förutsättning för kroppens kamp mot diverse sjukdomar orsakade av t ex virus och bakterier. En grundläggande egenskap hos immunsystemet är dess förmåga att skilja på vad som är kroppens egna celler och molekyler och vad som är främmande. Ibland fungerar inte denna diskriminering som den ska och In this thesis the role of major histocompatibility complex (Mhc) class II molecules in development of autoimmune disease such as rheumatoid arthritis (RA), was studied. By combining an experimental model for RA, collagen type II induced arthritis (CIA), with molecular biology methods the importance of polymorphism in Mhc class II genes for disease development was investigated. The Mhc region con

The distribution of the output error burst lengths from a Viterbi decoder is of particular interest in connection with concatenated coding systems, where the inner code is convolutional. From the expurgated, random, and sphere-packing exponents for block codes an upper bound on this distribution for the ensemble of periodically time-varying convolutional codes is obtained. Finally, the distributio

Soil pH is one of the most influential variables in soil, and is a powerful factor in influencing the size, activity and community structure of the soil microbial community. It was previously shown in a century old artificial pH gradient in an arable soil (pH 4.0-8.3) that bacterial growth is positively related to pH, while fungal growth increases with decreasing pH. In an attempt to elucidate som

The aim of this study is to review recent data on dietary fiber (DF) and the glycemic index (GI), with special focus on studies from the Nordic countries regarding cardiometabolic risk factors, type 2 diabetes, cardiovascular disease, cancer, and total mortality. In this study, recent guidelines and scientific background papers or updates on older reports on DF and GI published between 2000 and 20

This study examines the attempts made by one local government in China, Shenzhen, to improve its investment environment for foreign-invested enterprises through administrative reforms between 1980 and 1997. Three empirical questions are posed: what reforms have been undertaken, what effects have they had and how have changes in the organizational environment affected them. The theoretical aim is

OBJECTIVE: To assess whether intravascular ultrasound (IVUS), used systematically in a series of patients with abdominal aortic aneurysms (AAA), is a feasible control procedure to ensure correct transfemoral placement of endovascular stent grafts (TPEG). DESIGN: Descriptive study. MATERIALS AND METHODS: Fourteen patients with infrarenal aortic aneurysms were treated by the placement of one tube gr

In this article we propose a modification of the recently introduced divergence information criterion (DIC, Mattheou et al., 2009) for the determination of the order of an autoregressive process and show that it is an asymptotically unbiased estimator of the expected overall discrepancy, a nonnegative quantity that measures the distance between the true unknown model and a fitted approximating mod

A search for a fermiophobic Higgs boson using diphoton events produced in proton-proton collisions at a centre-of-mass energy of root s = 7 TeV is performed using data corresponding to an integrated luminosity of 4.9 fb(-1) collected by the ATLAS experiment at the Large Hadron Collider. A specific benchmark model is considered where all the fermion couplings to the Higgs boson are set to zero and

This review summarises the evidence for the treatment of displaced fractures of the femoral neck in elderly patients. Results from randomised clinical trials and national register studies are presented when available. The advantages of arthroplasty compared with internal fixation are supported by several studies. A number of studies contribute to the discussions of total hip arthroplasty (THA) ver

A new Reference Material (RM) for radionuclides in mussel (Mytilus galloprovincialis) from the Mediterranean Sea (IAEA-437) is described and the results of the certification process are presented. Four radionuclides (K-40, U-234, U-238, and Pu239+240) have been certified, and information values on massic activities with 95% confidence intervals are given for nine radionuclides (Cs-137, Pb-210(Po-2

In some Wireless Sensor Network (WSN) deployments, nodes may be used for different purposes (sensing, data pre-processing, actuation, etc.). Even if such a network is organised into clusters, this creates heterogeneity in terms of energy capability, which needs to be managed and balanced in order to ensure proper sensing capability with maximised lifespan. In this paper, we present Routing based o

Context. The Gaia satellite will observe about one billion stars and other point-like sources. The astrometric core solution will determine the astrometric parameters (position, parallax, and proper motion) for a subset of these sources, using a global solution approach which must also include a large number of parameters for the satellite attitude and optical instrument. The accurate and efficien

The origin of two large peaks in the atmospheric radiocarbon ((14)C) concentration at AD 774/5 and 993/4 is still debated. There is consensus, however, that these features can only be explained by an increase in the atmospheric (14)C production rate due to an extraterrestrial event. Here we provide evidence that these peaks were most likely produced by extreme solar events, based on several new an

In this review, we analyze several types of graphene-based sensors for glucose detection with respect to their preparation, properties and efficiency in electro-chemical processes. Graphene may display different types of defects, which play a role in the electron transfer processes. Oxygenated groups on the edges of graphene planes reduce the graphene in-plane conductivity, but may enhance the het

The growing need for valid assessment procedures of the outdoor thermal environment in the fields of public weather services, public health systems, urban planning, tourism & recreation and climate impact research raised the idea to develop the Universal Thermal Climate Index UTCI based on the most recent scientific progress both in thermo-physiology and in heat exchange theory. Following exte

We study inhomogeneous random graphs in the subcritical case. Among other results, we derive an exact formula for the size of the largest connected component scaled by logn, with n being the size of the graph. This generalizes a result for the "rank-1 case". We also investigate branching processes associated with these graphs. In particular, we discover that the same well-known equation for the su