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The learning curve during repetitive production and the associated forgetting during production breaks are fundamental issues in the understanding of behavior. A model is suggested that combines 3 basic findings, namely, that single memory traces decay according to a power function of the retention interval, that aggregated memory traces can be combined by integration, and that the time to produce
Oligonucleotides are short fragments of RNA or DNA that can act as active pharmaceutical ingredients (API) in medicines used to target a wide range of diseases, with further applications continuously emerging. Solid Phase Oligonucleotide Synthesis (SPOS) remains the dominant platform for oligonucleotide production. However, SPOS is characterized by high reagent consumption and a poor sustainabilit
Almost 10 years have passed since microtektites and microkrystites were reported for the Paleocene–Eocene (P–E) boundary in drill cores and outcrop in New Jersey and in ODP Hole 1051B in the western North Atlantic. The glassy spherules were interpreted to reflect an impact trigger for the Paleocene–Eocene Thermal Maximum (PETM). Since then, many detailed studies of sediment strata across the P–E b
This paper advances scholarship on deliberate destabilisation for sustainability transitions. To understand how deliberate destabilisation plays out in practice, the politics of such processes must be confronted. To this end, we bridge research on the political economy of sustainability transitions with recent theorisations of the deliberate destabilisation of unsustainable socio-technical regimes
Following legislation in 2010, all Swedish teachers, at all levels, had a double mission: to teach democracy as well the content of their subject. This mission was seen as troublesome by evaluating authorities, among others. In the latest state curriculum, rhetoric has re-emerged as a central element of Swedish mother-tongue high school education and is also seen as troublesome. In this article we
We present the design, prototype developments and test results of the new time-of-flight detector (ToFD) which is part of the R3B experimental setup at GSI and FAIR, Darmstadt, Germany. The ToFD detector is able to detect heavy-ion residues of all charges at relativistic energies with a relative energy precision σΔE/ΔE of up to 1% and a time precision of up to 14 ps (sigma). Together with an
Multi-gigawatt-scale hydrogen production by water electrolysis is central in the green transition when it comes to storage of energy and forming the basis for sustainable fuels and materials. Alkaline water electrolysis plays a key role in this context, as the scale of implementation is not limited by the availability of scarce and expensive raw materials. Even though it is a mature technology, th
This paper introduces the use of a multi-zone modelling approach for analysing smoke spread in tunnels. The approach suggested in this paper is based on an existing model, i.e., the Multi-Zone Fire model developed for large spaces. The Multi-Zone Fire model has been adapted and modified for tunnel fire scenarios by including features that consider longitudinal ventilation flow, tunnel gradient and
INTRODUCTION: Treatment efficacy of reflex syncope is mainly related to the mechanism underlying syncope rather than its etiology or clinical presentation. The predominant mechanism underlying reflex syncope can be assigned to hypotensive or to bradycardic phenotypes.AREAS COVERED: Methodology and diagnostic criteria of the most useful tests for the identification of hypotensive and bradycardic ph
BACKGROUND: Transient tachypnoea of the newborn (TTN) is characterized by tachypnoea and signs of respiratory distress. Transient tachypnoea typically appears within the first two hours of life in term and late preterm newborns. The administration of corticosteroids might compensate for the impaired hormonal changes which occur when infants are delivered late preterm, or at term but before the ons
With the increasing number of IoT devices deployed, the problem of switching ownership of devices is becoming more apparent. Especially, there is a need for transfer protocols not only addressing a single unit ownership transfer but secure transfer of a complete infrastructure of IoT units including also resource constraint devices. In this paper we present our novel ownership transfer protocol fo
This article describes the development and deployment of Physics Toolbox Play, a gamified component of the Android Physics Toolbox Sensor Suite app, that can introduce young children through adults to fundamental physics principles. The app was used successfully in a variety of contexts, including STEM fairs with primary and secondary students and workshops with undergraduate physics majors and pr
The European Spallation Source Neutrino Super Beam (ESSνSB) project aims at a discovery of leptonic CP violation with a precise measurement of the CP phase angle. ESSνSB is characterized by an intense neutrino beam to be produced at ESS by a 5-MW proton beam, and the placement of the far detector at the second oscillation maximum. The aims of the near detector for ESSνSB are neutrino flux and inte
The conflict between Armenia and Azerbaijan over Nagorno-Karabakh has put the Islamic regime of Iran in a difficult position. While the government is trying to be neutral, other regime elements have openly taken sides in the conflict.
(equation presented) The synthesis of α-substituted α,β-enones by a new metal iodide-promoted one-pot three-component reaction involving commercially available cyclopropyl ketones, aldehydes, and secondary amines followed by base treatment is described.
This article analyses the evolution of public support for the single European currency, the euro, from 1990 to 2014 for a 12-country sample of the euro area (EA-12), focusing on the most recent period of the financial and sovereign debt crisis, starting in 2008. We find that citizens’ support for the euro on average was marginally reduced during the first six years of the crisis, and that support
Starting from next year the technical feasibility of a direct seeding scheme at 30 and 13 nm will be studied at the Free-electron LASer in Hamburg (FLASH). During a major shutdown the SASE-FEL facility will be upgraded and it is planned to install in addition a high-harmonic generation (HHG) seed laser, a new chain of 10 m variable gap un-dulators and a dedicated commissioning beamline for photon
