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Pulchrol (1) is a natural benzochromene isolated from the roots of Bourreria pulchra, shown to possess potent antiparasitic activity towards both Leishmania and Trypanozoma species. As it is not understood which molecular features of 1 are important for the antiparasitic activity, several analogues were synthesized and assayed. The ultimate goal is to understand the structure-activity relationship
For most people getting a stroller is an obvious thing to do when having a baby. It’s mainly used for transportation of the baby but has other functions as well. For example, it is used as a storage, serves as a shopping bag for groceries and makes a perfect bed for a baby nap. Using a stroller should be easy and safe, but when it’s getting dark outside it can be hard to see the road ahead and fin
This thesis aims to explore the issue of trademark squatting and its solutions in the EU and China. Trademark squatting is a form of trademark infringement that occurs when individuals or entities register trademarks in territories where they do not have legitimate business operations, taking advantage of the "first-to-file" systems. If trademark squatting is permitted to persist, it has
The purpose of this thesis was to determine how a heavy duty vehicle manufacturer can create an economical viable business model for used batteries from electric buses and trucks. Heavy duty vehicles are responsible for 30% of on-road CO2 emissions in the European Union, but could be decreased if this sector would be electrified. One major barrier for this transition is the large cost for the batt
This thesis examines a local low-carbon energy transition in an urban context with regard to energy justice. It takes the Vauban district in Freiburg (Germany) as a case study which has been described as a successful case of energy transition and a model for sustainable urban development. From a theoretical point of view, energy justice encompasses a fair distribution of costs and benefits of an e
Thesis purpose: The purpose of the master thesis is to analyse the battle of meaning creation regarding the notion of smoking and to reveal the production of unequal power relations. The battle is fought by different stakeholders through means of language and the study focuses on the tobacco industry in Germany. Methodology: A critical discourse analysis is applied with a qualitative research stra
The engineers at Westinghouse Electric Company have developed a new nuclear fuel design called TRITON11™, which will be used in Boiling Water Reactors (BWR). This project has been to develop a test program and an assembly fixture for TRITON11™. The test program can not be fully presented in this repport due to confidentiality. The test program is for the first scoping test that will be performed o
The NDVI time-series consist of trend, season and noise. Changes in the season component are related to climate factors and they happen gradually over long period of time. The changes in the trend component are often due to human activities, fires and etc. This paper implements two algorithms (PolyTrend and DBEST) in R language, in order to examine the vegetation changes in the Middle East and to
The purpose of this paper was to research how environmental concerns and sustainable thinking could be integrated into the design process of Electrolux, a Swedish home appliance manufacturer. The research will hopefully help the Electrolux industrial design department improve in the area and prove as a good case study for other companies or academic institutions. Electrolux conducts much research
This master thesis maps and discusses the current and future needs, wishes and challenges of office workers. The resultant contextual knowledge is utilized to develop a concept of an office chair. The work followed an exploratory design process. Initially, literature and data on various topics were researched to form an understanding of the current and future working conditions of office workers.
Inside the human body, cells produce long sugar chains called glycosaminoglycans, or named shortly as GAGs, these sugars play an important role in our body since they are involved in important biological processes such as blood coagulation, being components in our cartilage, and the new development of tissues. Changes in these sugars is associated with several diseases such as in some kinds of can
The Standard Model does not predict the quantization of electric charge, and thus does not explicitly demand the electric neutrality of the neutron. This charge has previously been measured to an upper limit of ∼ 1 × 10^−21 elementary charges in a 1988 joint experiment between the University of Bayreuth and Institut Laue-Langevin [1]. A new experiment proposed for the HIBEAM beamline at the ESS is
Diverse organophosphate hydrolases have convergently evolved the ability to hydrolyse man-made organophosphates. Thus, these enzymes are attractive model systems for studying the factors shaping enzyme functional evolution. Methyl parathion hydrolase (MPH) is an enzyme from the metallo-β-lactamase superfamily, which hydrolyses a wide range of organophosphate, aryl ester and lactone substrates. In
Multivariate random sums appear in many scientific fields, most notably in actuarial science, where they model both the number of claims and their sizes. Unfortunately, they pose severe inferential problems. For example, their density function is analytically intractable, in the general case, thus preventing likelihood inference. In this paper, we address the problem by the method of moments, unde
Vertebrate photoreceptors have been studied for well over a century, but a fixed nomenclature for referring to orthologous cell types across diverse species has been lacking. Instead, photoreceptors have been variably—and often confusingly—named according to morphology, presence/absence of ‘rhodopsin’, spectral sensitivity, chromophore usage, and/or the gene family of the opsin(s) they express. He
The road freight sector’s significant contribution to greenhouse gas emissions necessitates emission mitigating strategies to meet climate targets, such as the Paris Agreement’s goal of 43% emission reduction. While Battery Electric Trucks (BETs) show great potential to reach these goals, their successful integration hinges on optimization and route planning. This thesis investigates the condition
