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Turkish President Erdogan is a faithful Muslim and strongly objects to getting/paying interest. To reduce the (high) inflation rate, he declared in a speech at Parliament: “As long as I am in office, I will fight interest. The NAS is there.” The primary purpose of this chapter is to shed light on the nature of this concept and to find out whether there is indeed a NAS with the specific aim of curb

Generation Z (Gen Z) will soon become the biggest living generation and the most dominant in terms of population and economic power, making them one of the tourism industry’s fastest-growing segments and a crucial market to target. There is growing evidence that Gen Z is concerned about the environmental and social effects of their consumption and is guided by strong ethical and environmental idea

Articial intelligence (AI) is widely discussed across policy sectors, including global environmental politics. At the 28th United Nations Climate Change Conference in 2023 (COP28), national governments decided to explore AI’s role in climate solutions and its associated challenges and risks through the #AI4ClimateAction Initiative. In March 2024, the UN General Assembly adopted a resolution to “se

G protein-coupled receptor (GPR)-39 is a seven-transmembrane receptor expressed mainly in endocrine and metabolic tissues that acts as a Zn++ sensor signaling mainly through the G(q) and G(12/13) pathways. The expression of GPR39 is regulated by hepatocyte nuclear factor (HNF)-1 alpha and HNF-4 alpha, and in the present study, we addressed the importance of GPR39 for glucose homeostasis and pancre

OBJECTIVE Plasma metabolites that distinguish isolated impaired glucose tolerance (iIGT) from isolated impaired fasting glucose (iIFG) may be useful biomarkers to predict IGT, a high-risk state for the development of type 2 diabetes. RESEARCH DESIGN AND METHODS Targeted metabolomics with 23 metabolites previously associated with dysglycemia was performed with fasting plasma samples from subjects w

The genomic conflict between the sexes is caused by differences in the optimal male and female reproductive strategies, and is a major contributor to genetic, phenotypic, and life history variation. While early experimental work appeared to strongly support predictions from sexual conflict, recent work has produced more ambiguous results. Recent advances in experimental evolution studies combined

PARP14 is a mono-ADP-ribosyl transferase involved in the control of immunity, transcription, and DNA replication stress management. However, little is known about the ADP-ribosylation activity of PARP14, including its substrate specificity or how PARP14-dependent ADP-ribosylation is reversed. We show that PARP14 is a dual-function enzyme with both ADP-ribosyl transferase and hydrolase activity act

Social media has opened up a new tactical front for political campaigns, and the 2017 General Election showed how citizens – armed with smartphones, computers, and tablets – actively enlisted their support in the online electoral battleground. In this report, we look at how Labour supporters leveraged the platform-specific features of different social media to widely promote their favored candidat

Lineage plasticity is recognized as a critical determinant of lethality and resistance to AR pathway inhibitors in prostate cancer. Lineage plasticity is a continuum, ranging from AR activity-low tumors, AR-null tumors that do not express a neuroendocrine prostate cancer (NEPC) program (i.e., double-negative prostate cancer [DNPC]), and AR-null NEPC tumors. Factors upregulated early in lineage pla

Objective: Progressive multiple sclerosis is characterized by chronic inflammation with microglial activation, oxidative stress, accumulation of iron and continuous neurodegeneration with inadequate effectiveness of medications used so far. We now investigated effects of iron on microglia and used the previously identified neuroprotective antipsychotic clozapine in vitro and in chronic experimenta