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Background: The aim was to evaluate whether an artificial intelligence (AI)-based tool for the automated quantification of the total metabolic tumour volume (tMTV) in patients with Hodgkin lymphoma (HL) could support nuclear medicine specialists in lesion segmentation and thereby enhance inter-observer agreement. Methods: Forty-eight consecutive patients who underwent staging with [18F]FDG PET/CT

Hard turning offers a cost-effective alternative to traditional grinding, yet the tool wear progression limits the broader industrial adoption. During hard turning, the surface microstructure of AISI 52100 steel transforms into a nanocrystalline structure known as white layer, accompanied by significant surface residual stresses. With optimal cutting conditions, surfaces develop nanocrystalline mi

Background: Pancreatic ductal adenocarcinoma (PDAC) is characterized by a prominent desmoplastic stroma, which plays a crucial role in tumor biology and treatment resistance. While the stromal compartment is a defining histopathological feature of PDAC, its prognostic significance remains incompletely understood. This study aimed to quantify the stromal content in PDAC using digital pathology and

Objectives: To describe the rationale, design and data collection procedures of the Swedish CArdioPulmonary bioImage Study (SCAPIS) re-examination, which, in its further scope, aims to quantify and explain the development of atherosclerosis, pathological cardiovascular ageing, longitudinal decline in lung function and the malignant transformation of pulmonary nodules among middle-aged Swedes in th

Objectives The aim was to estimate the prevalence and risk of respiratory symptoms among workers exposed to epoxy resin systems in the wind turbine industry. Methods We conducted a cross-sectional study including 180 epoxy-exposed production workers from two Danish wind turbine blade factories and 41 non-exposed office workers. Respiratory symptoms were defined as having two or more symptoms (i.e.

Background Parenthood is consistently identified as a protective factor for suicidal behavior. However, it remains unclear whether this relationship varies as a function of sex, age, time since birth, number of children, and other risk/protective factors. Methods We used Cox proportional hazards models to describe the relationship between the birth of up to four children and suicide attempt (SA) r

AIMS: A history of preeclampsia is associated with at least a twofold increased risk of coronary artery disease (CAD), with unclear underlying mechanisms. This study aimed to investigate coronary plaque characteristics in women with a history of preeclampsia compared to women from the general population.METHODS: In this cross-sectional study, women with a history of preeclampsia from the Cardiovas

BACKGROUND/OBJECTIVES: Iron deficiency has been suggested as a potential mechanism for attention-deficit hyperactivity disorder (ADHD) development due to involvement in neurotransmitter synthesis and transporter expression. As iron deficiency is particularly common in women of reproductive age, often due to heavy menstrual bleeding (HMB), we aimed to explore the relationship between iron deficienc

The first measurement of the e+e− pair production at midrapidity and low invariant mass in central Pb-Pb collisions at √sNN = 5.02 TeV at the Large Hadron Collider is presented. The yield of e+e− pairs is compared with a cocktail of expected hadronic decay contributions in the invariant mass (mee) and pair transverse momentum (pT,ee) ranges mee < 3.5 GeV/c2 and pT,ee < 8 GeV/c. For 0.18 < mee < 0.

Background: Black carbon (BC) is an air pollutant of growing concern due to its adverse impacts on health and climate. Growing evidence suggests that BC could have a number of negative impacts on morbidity and mortality, but more evidence is needed. Objective: The objectives of this study are to quantify any associations between BC exposure and cause-specific (cardiovascular and cancer) mortality

Background and aims Secondary prevention medications after myocardial infarction (MI) are crucial for reducing mortality and cardiovascular events, however, adherence is often suboptimal. This study aimed to investigate predictors of adherence, and clinical outcomes among STEMI and NSTEMI survivors in Sweden. Methods This nationwide cohort study included patients hospitalized with MI between 2017

Background: Physical exercise is part of the recommended treatment for individuals with axial spondyloarthritis (axSpA). High-intensity interval training (HIIT) is an effective way to improve cardiovascular health without risk of increased disease activity. Nevertheless, there is a lack of knowledge regarding facilitating factors for digitally-based HIIT among individuals with axSpA. Objective: Th

Purpose: The purposes are to evaluate the change in mammographic density within individuals across screening rounds using automatic density software, to evaluate whether a change in breast density is associated with a future breast cancer diagnosis, and to provide insight into breast density evolution. Approach: Mammographic breast density was analyzed in women screened in Malmö, Sweden, between 2

BACKGROUND: The management of femoral neck fractures (FNF) in elderly patients depends on comorbidities, pre-fracture mobility, any hip joint disease, and life expectancy, with treatment typically involving either hemiarthroplasty (HA) or total hip arthroplasty (THA). While cemented femoral stem fixation is standard, there is no clear consensus regarding cemented versus cementless cup fixation in

OBJECTIVE: Screening for abdominal aortic aneurysm (AAA) using ultrasound in men reduces aneurysm-related mortality. Ambulatory screening and surveillance procedures facilitated by point-of-care ultrasound (POCUS) may improve adherence to screening programs. This proof-of-concept study evaluated whether infrarenal aortic diameter (IAD) can be accurately and interchangeably measured using handheld

Coffee is epidemiologically linked to health benefits and risks. Coffee is thought to be a diuretic. However, it can still contribute to daily fluid intake. Vasopressin is the most important physiological regulator of body fluid balance and diuresis. This study aimed to map the effects of coffee intake on vasopressin concentration. In the population-based cross-sectional Malmö Offspring Study (n =

Background and Aims: Implantable cardioverter-defibrillators (ICDs) are critical for preventing sudden cardiac death (SCD) in arrhythmogenic right ventricular cardiomyopathy (ARVC). This study aims to identify cross-continental differences in utilization of primary prevention ICDs and survival free from sustained ventricular arrhythmia (VA) in ARVC. Methods: This was a retrospective analysis of AR

Background This study aimed to describe the incidence rate, patient characteristics, treatments, and outcomes of adults hospitalized with Mycoplasma pneumoniae pneumonia. Methods This retrospective cohort study included adults diagnosed with M pneumoniae pneumonia and admitted to emergency care hospitals in Stockholm County, Sweden, from 2013 to 2017. Patients were identified through positive M pn

Background: Low adherence to lipid-lowering therapy (LLT) after myocardial infarction (MI) is associated with increased risk of recurrent cardiovascular events and death. However, little is known about long-term adherence patterns following treatment interruptions. The aim of this study was to describe adherence trajectories in MI patients following a LLT treatment gap, and model the impact of dif

Background Endoscopic papillectomy is a standard treatment for ampullary lesions, which are typically small and confined to the papillary mound. Laterally spreading lesions (LSLs) of the papilla of Vater are a rare ampullary lesion subtype involving extensive duodenal mucosa. Data on endoscopic papillectomy outcomes for LSLs are limited. This study compared endoscopic papillectomy for ampullary LS