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BACKGROUND: Type 2 diabetes often displays hyperlipidemia. We examined palmitate effects on pancreatic islet function in relation to FFA receptor GPR40, NO generation, insulin release, and the PPARgamma agonistic thiazolidinedione, rosiglitazone. PRINCIPAL FINDINGS: Rosiglitazone suppressed acute palmitate-stimulated GPR40-transduced PI hydrolysis in HEK293 cells and insulin release from MIN6c cel
Background: Type 2 diabetes often displays hyperlipidemia. We examined palmitate effects on pancreatic islet function in relation to FFA receptor GPR40, NO generation, insulin release, and the PPARgama agonistic thiazolidinedione, rosiglitazone. Principal findings: Rosiglitazone suppressed acute palmitate-stimulated GPR40-transduced PI hydrolysis in HEK293 cells and insulin release from MIN6c cell
NYTT FRÅN LUNDS UNIVERSITET Mejlutskick på svenska och engelska som vänder sig till fakultetskommunikatörer vid Lunds universitet för vidarespridning i fakultets- och institutionskanaler – Nr 20 v 22 - 2021. UNIVERSITETSGEMENSAMT Lönerevisionen drar ut på tiden Förhandlingarna med anledning av lönerevisionen pågår fortfarande. Tyvärr kan det konstateras att det nu har dragit ut så långt i tiden at
https://www.cec.lu.se/sites/cec.lu.se/files/2021-06/LU-gemensamt%20Mejlutskick%20Nr%2020-v22-2021.pdf - 2026-07-23
How should we respond to a criminal offence committed by a young person? It is obvious that this is a very complex question. Multiple factors play important roles: the offence itself, but also the juvenile’s background in terms of education, socialization, prior convictions, etc. Every case is unique, but the criminal legal system has to follow the principles of legal certainty and predictability.
A key question for evidence-based medicine (EBM) is how best to model the way in which EBM should‘[integrate] individual clinical expertise and the best external evidence’. We argue that the formulations and models available in the literature today are modest variations on a common theme and face very similar problems when it comes to risk analysis, which is here understood as a decision procedure
BackgroundTo explore the cytotoxic and apoptotic activity of the pierisin-6 protein in HPV HeLa and HepG2 cell lines.MethodsIn this study, isolation, and purification of cytotoxic Prierisin-6 from the larvae of Pieris napi by affinity column chromatography techniques. Characterization of full-length mRNA of pierisin-6 gene was performed using 3'/5' RACE PCR. The quantitative RT-PCR used to study t
It is widely assumed that there is a natural, prelinguistic conceptual domain of time whose linguistic organization is universally structured via metaphoric mapping from the lexicon and grammar of space and motion. We challenge this assumption on the basis of our research on the Amondawa (Tupi Kawahib) language and culture of Amazonia. Using both observational data and structured field linguistic
Expression of fibroblast growth factor 8 (FGF-8) is increased in several forms of hormonal cancer. It was previously shown to regulate expression of thrombospondin 1 (TSP-1), an inhibitor of angiogencsis, in S115 breast cancer cells. Here, we studied the FGF-8-activated signalling pathways mediating TSP-1 repression in S115 cells and in non-tumorigenic MCF10A cells. Inhibition of FGF receptors or
In this volume of “Lecture Notes in Intelligent Transportation and Infrastructure”, the proceedings of the International Conference “Vision Zero for Sustainable Road Safety in Baltic Sea Region”, which took place in Vilnius, Lithuania, from 5 to 6 December 2018, are presented. The mission of the conference was to promote a more comprehensive approach supporting new ideas, technologies, theories, i
Sustainable energy storage and conversion utforskar innovativa metoder för att effektivt lagra och omvandla energi från olika förnybara källor. Fokus ligger på teknik som avancerade batterier, vätgasproduktion, bränsleceller och termokemiska system samt säkerhetsaspekter på batterilagringssystem. Forskningen syftar till att öka energitätheten, minska kostnaderna och förbättra skalbarheten, vilket
https://www.energy.lth.se/sv/forskning/lagring-och-omvandling-av-energi - 2026-07-23
