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-The atrial switch operation Mustard- or Senning operation for transposition of the great arteries (TGA) was introduced in the late 1950s and was the preferred surgery for TGA until the early 1990s. The Mustard- and Senning operation involves extensive surgery in the atria and leaves the right ventricle as the systemic ventricle. The Mustard and Senning cohort is now well into adulthood and we beg
Projects often suffer from lack of logistics considerations in the early phases. Since logistics is not the main focus of the people involved in the project, logistics solutions become reactive rather than proactive. With the increasing global competition, forcing companies to shorten time-to-market for their projects and becoming more cost effective, it becomes increasingly important to manage pr
Colonialism’ and ‘decolonization’ have been dealt with by postcolonial studies and, more recently, by scholars identified with the ‘de-colonial turn’. At the same time, in the ethnopolitically charged context of contemporary Bolivian society, colonialism and decolonization have become issues of political, existential and even cosmological import. This thesis identifies a need to root the ‘de-colon
The partitioning of 10% (w/w) lactic acid in ethylene oxide propylene oxide (EOPO) random copolymers and dextran T500 aqueous two-phase systems was studied. An analysis of variance design was applied to investigate the effect of pH, polymer concentration, and addition of polyethyleneimine to the aqueous two-phase systems. The lowest lactate partition coefficient of 0.09 was obtained at pH 6 in the
Artikeln diskuterar en föga uppmärksammad paradox inom etiken: Etiska teorier söker övervinna moralisk oenighet och bristande efterlevnad, men de lever på sitt misslyckande att åstadkomma detta. Om alla skulle handla efter universellt accepterade moraliska principer blev moralen ointressant. Kontraktsetiska teorier kan bidra till att förstå denna aspekt av etiken. Enligt dessa uppstår etiska probl
In this paper a simple analytical method is introduced for calculating the overall thermal conductivity of a twin pipe in district heating network. The method is developed based on calculating the conductive and convective heat transfer around the casing pipe in different perimetral sections. Temperature inside the supply and return pipes and also over the heating pipe is measured on different poi
Sepsis is a systemic immune response responsible for considerable morbidity and mortality. Molecular modeling of host-pathogen interactions in the disease state represents a promising strategy to define molecular events of importance for the transition from superficial to invasive infectious diseases. Here we used the Gram-positive bacterium Streptococcus pyogenes as a model system to establish a
Energy-intensive processing industries (EPIs) produce iron and steel, aluminum, chemicals, cement, glass, and paper and pulp and are responsible for a large share of global greenhouse gas emissions. To meet 2050 emission targets, an accelerated transition towards deep decarbonization is required in these industries. Insights from sociotechnical and innovation systems perspectives are needed to bet
Antigenic diversity in pathogenic microbes can be a result of at least three different processes: diversifying selection by acquired immunity, host–pathogen coevolution and/or host specialization. Here, we investigate whether host specialization drives diversity at ospC (which encodes an immunodominant surface protein) in the tick-transmitted bacterium Borrelia afzelii. We determined prevalence an
The capacity of communities to reduce negative impacts of climate change on their lives and livelihoods is a function of socio-economic conditions, infrastructure, government accountability and institutional responsiveness and not the least social capital. Africa’s most densely populated region, the Lake Victoria basin (LVB), home to over 30 million people, is one example of a likely future climat
The aim of the study was to explore what adolescents with congenital heart disease (CHD) view as important in the preparation for the transfer to adult care. We performed interviews in four focus groups with adolescents (14–18 years old) at four university hospitals in Sweden. Data was analysed using qualitative content analysis. The analysis revealed one main category; Becoming a manager of the c
The ability to rapidly detect cell free circulating (cfc) DNA and other nanoparticulate disease biomarkers directly in blood is a major challenge for nanomedicine. We now show that AC Electrokinetic (ACE) microelectrode array devices can be used to rapidly isolate and detect cfc-DNA nanoparticulates directly from whole blood and other high conductance samples (plasma, serum etc.). The device shows
