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Purpose: The FANCM c.5101C>T nonsense mutation was previously found to associate with breast cancer in the Finnish population, especially among triple-negative cases. Here, we studied the prevalence of three other FANCM variants: c.5791C>T, which has been reported to predispose to familial breast cancer, and the c.4025_4026delCT and c.5293dupA variants recently identified in Finnish cancer patient

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Pigment epithelium derived factor (PEDF), a ubiquitously expressed 50 kDa secreted glycoprotein, was recently discovered to regulate self-renewal of neural stem cells and have a supportive effect on human embryonic stem cell growth. Here, we analyzed expression of PEDF in the murine hematopoietic stem cell (HSC) compartments and found that PEDF is highly expressed in primary long-term HSCs. Theref

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Chemokines are important in the development and progression of tumors. We investigated the expression of CXCL14 and CXCL16 in colon cancer. Expression of mRNA was assessed in primary tumors and lymph nodes and CXCL16 mRNA levels were correlated to patient’s survival. Protein expression was investigated by two-color immunofluorescence and immunomorphometry. CXCL14 and CXCL16 mRNA levels and protein

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Fredrik NG Andersson and Lars Jonung argue that the current push for fiscal activism is short-sighted. Instead, the Swedish case from the last 25 years shows that stable public finances combined with supply-side policies is the recipe for economic stability and growth.

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WNT5A is a well-known mediator of melanoma cell invasion and metastasis via its ability to activate protein kinase C (PKC), which is monitored by phosphorylation of the endogenous PKC substrate myristoylated alanine-rich c-kinase substrate (MARCKS). However, a possible direct contribution of MARCKS in WNT5A-mediated melanoma cell invasion has not been investigated. Analyses of melanoma patient dat

Diagnostisk radiologi, Lund

Applikationer av modern radiologisk metodik i klinisk verksamhet (magnetisk resonanstomografi, datortomografi, ultraljud, scintigrafi, digital angiografi, bildplatteteknik, stereofotogrammetri). Interventionell radiologi och interventionell neuroradiologi; radiologisk leverdiagnostik; pediatrisk thoraxradiologi; pediatrisk ortopedi; radiologisk bedömning av rörelseorganens inflammatoriska, degenerThe Department of Diagnostic Radiology, Institution of Clinical Sciences conduct research in the field of diagnostic and therapeutic radiology and several of our researchers is affiliated with the Department of Imaging and Function at University hospital of Lund. In several research projects colleagues affiliated with our department collaborates with Medical Radiation Physics and LBIC (Lund Bioima

Redovisning och finans

Redovisning- och finansieringsområdet omfattar forskning inom ett brett fält från ekonomi- och verksamhetsstyrning, redovisning, revision, finansiell kommunikation, bolagsstyrning till forskning om företagsfinansiering, riskhantering och investerarrelationer.The accounting and corporate finance research covers a broad field from management accounting and control, financial accounting, financial communication and sustainability reporting to corporate governance, corporate financing, corporate risk management and investor relations.

Lunds Tekniska Högskola

LTH – en plats för drömmar och upptäckter På LTH utbildar vi människor, bygger kunskap för framtiden och arbetar hårt för att utveckla samhället. Vi skapar utrymme för briljant forskning och inspirerar till kreativ utveckling av teknik, arkitektur och design. Här läser närmare 10 000 studenter. Varje år publicerar LTH:s forskare omkring 100 avhandlingar och 2 000 vetenskapliga rön. En rad forskninThe Faculty of Engineering (LTH) – A place for dreams and discoveries At LTH, we educate people, build knowledge for the future and work hard to develop society. We create space for brilliant research and inspire creative development of technology, architecture and design. LTH has nearly 10,000 students. Every year, researchers at LTH publishes around 100 theses and 2 000 scientific findings. In a

Sektionen Globalt engagemang

Sektionen Globalt engagemang arbetar med att ge stöd och service till universitetets ledning, fakulteter eller motsvarande samt studenter för att stärka och utveckla Lunds universitets internationella genomslag inom forskning, utbildning, innovation och samverkan. Sektionen arbetar med att utveckla och implementera internationella strategier genom arbetet med Global Dynamic Engagement (GDE) men The Division of Global Engagement provides support and services to the university leadership, faculties, or equivalents, as well as students, to strengthen and develop Lund University's international impact in research, education, innovation, and collaboration. The division works with developing and implementing international strategies through the work with Global Dynamic Engagement (GDE), Global

Klinisk koagulationsmedicin, Malmö

Peter Svensson är forskargruppsledare för den här forskargruppenThe Clinical Coagulation Research Unit in Malmö is managing several projects in the fields of thrombosis and bleeding disorders. Research in thrombosis includes epidemiological investigation into coagulation disorders, and research concerning different types and combinations of anticoagulant treatment. In the field of bleeding there are projects concerned with haemophilia, von Willebrand's disease

Mikrobiell biogeokemi i Lund

Vi studerar terrestra ekosystem för att bättre förstå hur markmikroorganismer reglerar global biogeokemi och för att förutsäga reaktioner på miljöförändringar. Vi är en grupp mikrobiella ekologer, ekosystemekologer, biogeokemister och modellerare, som har en gemensam vision och under paraplyet "Microbial Biogeochemistry in Lund", kombinerar empiriska och modellerande tillvägagångssätt för att åstWe study terrestrial ecosystems to better understand how soil microorganisms regulate global biogeochemistry and predict responses to environmental changes. We are a group of microbial ecologists, ecosystem ecologists, biogeochemists, and modellers, who have a shared vision, and under the umbrella of "Microbial Biogeochemistry in Lund", combine empirical and modelling approaches to accomplish th