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OBJECTIVE: Critical limb ischemia (CLI) is a peripheral arterial disease manifested by drastically diminished blood flow to the legs, pain at rest, nonhealing wounds, and gangrene caused by atherosclerosis. Significant tissue necrosis is associated with late stage CLI and the patients have a poor prognosis. Necrotic and apoptotic cells activate complement and bind complement inhibitor C4b-binding
The Nordic medical birth registers have long been used for valuable clinical research. Their collection of data for more than four decades offers unusual possibilities for research across generations. At the same time, serum and blotting paper blood samples have been stored from most neonates. Two large cohorts (approximately 100000 births) in Denmark and Norway have been described by questionnair
We review some recent results on the exact asymptotics of the components in the inhomogeneous random graph models of rank 1. We discuss the relevance of these results to the analysis of random walk on random graphs.
Building big data analytics applications (BDA) in the Cloud introduces inevitable challenges such as loss of control and uncertainty. To address the existing challenges, numerous efforts have been made on BDA application engineering to optimise quality of BDA applications in the Cloud, such as performance and reliability. However, there is still a lack of systematic view on engineering BDA applica
Background: Although widely used, the validity and reliability of the Clavien classification of postoperative complications have not been tested in urologic procedures, such as percutaneous nephrolithotomy (PCNL). Objective: To validate the Clavien score and categorise complications of PCNL. Design, setting, and participants: Data for 528 patients with complications after PCNL were used to create
A novel rapid methodology for determining the chemical oxygen demand (COD) based on a thermal sensor with a flow injection analysis system was proposed and experimentally validated. The ability of this sensor to detect and monitor COD was based on the degree of enthalpy increase when sodium hypochlorite reacted with the organic content in water samples. The measurement results were correlated with
The objective of this paper is to analyse the Constructive Dialogue, an initiative for collaborative and integrated urban governance for a sustainable built environment. The dialogue processes, implemented in six Swedish cities in 2004-2009, involved various actors and many types of initiative. Designed as a meta-analysis based on existing evaluations and supplementary interviews, this study exami
In order to make the hydrogen economy fully sustainable, renewable resources have to be employed for its production. Simulation models, developed with Aspen Plus to calculate mass and energy balances, will be used to integrate the process steps necessary to produce pure hydrogen from biomass in a 2-stage fermentation process. The main challenge is the reduction of water and heat demand connected t
This guideline for the investigation and initial treatment of atypical hemolytic uremic syndrome (HUS) is intended to offer an approach based on opinion, as evidence is lacking. It builds on the current ability to identify the etiology of specific diagnostic sub-groups of HUS. HUS in children is mostly due to infection, enterohemorrhagic Escherichia coli (EHEC), Shigella dysenteriae type 1 in some
The aim was to explore patients' experiences of information and their information needs after discharge for colorectal cancer surgery.
It is often suggested that the emittance coupling of a storage ring should be adjusted to the so-called diffraction limit corresponding to the shortest wavelength of interest. For 1 Å radiation this leads to a typical requirement of 8 pm rad vertical emittance. In ultralow-emittance storage rings like the MAX IV 3 GeV storage ring this corresponds to a comparably large setting of the emittance cou
The last ten years have seen a sharp increase in externally supported capacity development initiatives for disaster risk management. However, not all of them have generated sustainable results. The purpose of this paper is to scrutinize the current focus on training as the main tool for capacity development in the context of disaster risk management, and to argue for the necessity to address capac
The use of prosthetic hands are limited partly due to the fact that they lack the provision of sensory feedback to the user. A first step to providing sensory feedback is having adequate sensors in the prosthesis. The WiseSkin project targets the use of artificial skin embedding ultra-low power wireless sensor nodes. This paper provides an overview of the WiseSkin artificial skin for tactile prost
a) The use of a solid phase reaction (silver silicate) for avoiding ortho ester formation in some difficult glycosyl donor/acceptor systems. Thus seven monodeoxygenated analogues of 2-(Trimethylsilyl)ethyl betha-lactoside were synthesiszed. Silver silcate was successfully used in betha 1-4 coupling of 2- and 3-deoxy glucosides to to acetobromogalactose. By similar means, the monodeoxylactosyl brom
Energy efficiency scenarios are developed in the national and international context to explore and evaluate different policy designs and visions of how energy will be generated, distributed and used in the future. However, these scenarios are often developed using conventional bottom-up modelling tools that, to only a limited extent, take into account decentralised decision-making frameworks, such
