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Diffuse traumatic brain injury in mice is associated with a transient mismatch of cerebral blood flow and energy metabolism

Axonal injuries commonly contribute to poor functional outcomes following traumatic brain injury (TBI). To assess cerebral blood flow (CBF) and energy metabolic disturbances in a TBI model of widespread axonal injury, we exposed 105 adult mice to the central (midline) fluid percussion injury (cFPI) diffuse TBI model, or sham injury, and used 9.4 T magnetic resonance (MR) arterial spin labeling (AS

The current state of cranioplasty in Europe – Results from a European cranioplasty survey

Introduction: Cranioplasty, a surgical procedure to restore skull integrity and aesthetic contour following decompressive craniectomy, poses challenges in material selection and timing, driven by the lack of guidelines and ongoing regulatory changes. Research question: This study aimed to provide an overview of current cranioplasty practices in Europe, explicitly addressing a potential shift towar

Effects of Selective Head-and-Neck Cooling on Brain Injury-Related Biomarker Levels and Symptom Rating Following a Boxing Bout : Protocol for an Exploratory Randomized Trial

BACKGROUND: Head impacts are common in contact sports such as boxing and occur at times of elevated core body and brain temperatures induced by the exercise. Following impact, elevated brain temperature may lead to the development of exacerbated brain injury that can be monitored by blood biomarkers. Blood-brain biomarkers S100B and glial fibrillary acidic protein (GFAP) reflect glial injury; neur

Iron Cages; Liquid Scholars: : Exploring the valuable coordination of higher education scholarships in the international knowledge society

Denna avhandling breddar rådande förståelser av stipendier och deras systematiska användning inom internationell högre utbildning genom att introducera en ny uppsättning teoretiska verktyg för att undersöka sådana satsningar. Med fokus på organisationer i Mexiko och Indonesien samt de studenter de sponsrade till svenska masterprogram mellan 2013 och 2020, utforskar studien värderingsprocesser, samThis thesis broadens prevailing understandings of scholarships and their systematic use in international higher education, introducing a novel set of theoretical tools for examining such endeavors. Focusing on organizations in Mexico and Indonesia and the students they sponsored in Swedish master’s degree programs between 2013-20, the study explores valuation processes, coordination puzzles and et

Copeptin as a marker of outcome after cardiac arrest : A sub-study of the TTM trial

Background: Arginine vasopressin has complex actions in critically ill patients, involving vasoregulatory status, plasma volume, and cortisol levels. Copeptin, a surrogate marker for arginine vasopressin, has shown promising prognostic features in small observational studies and is used clinically for early rule out of acute coronary syndrome. The objective of this study was to explore the associa

Serology assessment of antibody response to SARS-CoV-2 in patients with COVID-19 by rapid IgM/IgG antibody test

The coronavirus disease 2019 (COVID-19) pandemic has created a global health- and economic crisis. Detection of antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which causes COVID-19 by serological methods is important to diagnose a current or resolved infection. In this study, we applied a rapid COVID-19 IgM/IgG antibody test and performed serology assessment of antibody

The Four-Kallikrein Panel Is Effective in Identifying Aggressive Prostate Cancer in a Multiethnic Population

BACKGROUND: The four-kallikrein (4K) panel has been demonstrated to improve prediction of aggressive prostate cancer compared with prostate-specific antigen (PSA) among men with moderately elevated PSA levels. However, the development and testing of the 4K panel has been conducted primarily in White men, with limited data in African Americans and no studies in other racial and ethnic groups. METHO

Increased circulating blood cell counts in combat-related PTSD : Associations with inflammation and PTSD severity

Inflammation is reported in post-traumatic stress disorder (PTSD). Few studies have investigated circulating blood cells that may contribute to inflammation. We assessed circulating platelets, white blood cells (WBC) and red blood cells (RBC) in PTSD and assessed their relationship to inflammation and symptom severity. One-hundred and sixty-three male combat-exposed veterans (82 PTSD, 81 non-PTSD)

A method for supporting the integration of packaging development into product development

This paper aims to support the decision-making tasks regarding the integration of packaging development into product development. Based on the study of the interactions of the product and packaging during the whole product life cycle, a set of packaging-related factors was extracted and mapped to a general product development model, which at a strategic level can be used to define an integrated pr

LPED 2019 1

Centre for Economic Demography Lund University School of Economics and Management P.O. Box 7083 SE-220 07 Lund, Sweden www.ed.lu/publications/Lund-Papers-in-Economic-Demography/ Do grandfathers really matter for social mobility? Evidence from Swedish register data JONAS HELGERTZ, MARTIN DRIBE LUND PAPERS IN ECONOMIC DEMOGRAPHY 2019:1 Copyright is held by the author(s). Lund Papers in Economic Demo

https://www.lusem.lu.se/sites/lusem.lu.se/files/2024-07/LPED_2019_1.pdf - 2026-05-17

Matchmaking Summary Knowledge For Sustainable Development 2021

Matchmaking contributions Content 1. Theme I: Knowledge on crisis and resilience in the sustainability context 2. Theme II: Knowledge on communicating uncertainty and ambiguity in sustainability research 3. Theme III: Knowledge about justice and equity in a sustainable world 4. Theme IV: Future Calls Matchmaking contributions Matchmaking event contribution Research Conference on Sustainable Develo

https://www.sustainability.lu.se/sites/sustainability.lu.se/files/2021-04/Matchmaking%20summary_Knowledge%20for%20Sustainable%20Development%202021.pdf - 2026-05-17

Intravascular vs. surface cooling in out-of-hospital cardiac arrest patients receiving hypothermia after hospital arrival : a post hoc analysis of the TTM2 trial

Purpose: To compare the performance of targeted temperature management (TTM) at 33 °C using intravascular (IC) vs. surface-cooling (SFC) devices after out-of-hospital cardiac arrest (OHCA). Methods: A post hoc analysis including OHCA patients randomized to hypothermia in the TTM2-trial (NCT02908308) comparing hypothermia with normothermia. The main outcome was cooling performance, defined as the p

The Prognostic and Treatment Predictive Value of Proliferation and TIMP-1 in Breast Cancer

Popular Abstract in Swedish Varje år insjuknar mer än 8000 kvinnor i Sverige i bröstcancer, och 5 år efter diagnos är nära 90% fortfarande i livet. Trots att prognosen för majoriteten av patienterna är god, dör 1400 kvinnor årligen av bröstcancer. Till följd av detta pågår mycket forskningsarbete för att finna faktorer som bättre kan förutsäga prognos, prognostiska studier, men även för att finna Breast cancer is the most common tumour form and the second leading cause of death in solid tumours in women in the Western world. Despite improvements in the treatment, a considerable number of patients will relapse and die from their breast cancer. At the same time, a substantial number of patients will be over-treated, as they would have been cured by surgery and radiotherapy alone. In the meta

Estimation of depth of fluorescing lesions in tissue from changes in fluorescence spectra

We present a novel method for estimating the depth of a fluorescent lesion in tissue based on measurements of the fluorescence signal in different wavelength bands. The measured fluorescence spectrum following irradiation by excitation light at the surface is a function of several parameters, because the fluorescence light has to pass through tissue with characteristic scattering and absorption pr

Ett nytt fackligt landskap - i Sverige och utomlands

Ur ett hundraårsperspektiv har arbetsmarknaden genomgått avsevärda förändringar. Majoriteten av löntagarna utgörs numera av tjänstemän. I Sverige svarar de även för majoriteten av fackmedlemmarna. De svenska fackföreningarna tillämpade redan tidigt en bred medlemsrekrytering, men till bilden hör också att Sverige har världens mest klassuppdelade fackliga rörelse. Inte minst för tjänstemännen har d

Assessment of Graft Effects and Function in Cell Replacement Therapy for Parkinson's Disease

Popular Abstract in Swedish Parkinsons sjukdom är en relativt vanlig kronisk neurologisk sjukdom som karaktäriseras av att nervceller i ett specifikt område djupt i hjärnan av okänd anledning successivt dör. Dessa celler producerar signalsubstansen dopamin, vilken bl a är nödvändig för normal rörelseförmåga. Motoriska symptom (skakningar, muskelstelhet, förlångsammade rörelser och balansstörningarThis explorative study aimed to apply, develop, and evaluate assessment methods at various levels in cell replacement therapy for Parkinson’s disease (PD). Observed motor effects in five grafted patients support that timed motor tasks and clinical ratings of parkinsonism are able to monitor motor function, but their psychometric properties need further attention. Using positron emission tomograp