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Traumatic brain injury (TBI) leads to intracerebral inflammation involving resident microglial cells and astrocytes as well as invading peripheral dendritic cells (DCs), monocytes, and neutrophils. However, the profile of immune blood cells activated by TBI remains poorly defined. Several animal models showing invasion of circulating classical dendritic cells type 2 (cDC2s) to the traumatically in

Background Exertional breathlessness is a limiting symptom that often coexists with anxiety and depression. We tested the hypothesis that anxiety and depression negatively impact exertional breathlessness in daily life and during standardised cardiopulmonary exercise testing (CPET). Methods Analysis of people aged ⩾40 years undergoing incremental cycle CPET. Exertional breathlessness in daily life

Background: Breathlessness on exertion is a common, distressing, and limiting symptom that can be quantified on incremental cardiopulmonary exercise testing (CPET) using normative reference equations. Research Question: Is the breathlessness abnormality best uncovered and assessed at symptom limitation (peak exercise) compared with submaximal exercise intensities? Study Design and Methods: This wa

Denna uppsats behandlar frågan om när sjukdom kan utgöra sakliga skäl för uppsägning enligt 7 § lagen (1982:80) om anställningsskydd (LAS). Utgångspunkten i svensk arbetsrätt är att sjukdom i sig inte utgör grund för uppsägning. Syftet är därför att klarlägga under vilka förutsättningar sjukdom ändå kan leda till en rättsenlig uppsägning. Uppsatsen bygger på en rättsdogmatisk metod där lagtext, föThis essay examines under what circumstances illness may constitute objective grounds for dismissal under Chapter 7, Section 1 of the Swedish Employment Protection Act (1982:80). The starting point in Swedish labour law is that illness as such does not justify dismissal. The purpose of the study is therefore to clarify the legal conditions under which illness may nonetheless result in a lawful ter

BACKGROUND: Neurointensive care is moving toward more automated patient management. This study aimed to evaluate a novel external ventricular drainage (EVD) system, the VGuard® system, as a tool for intracranial pressure (ICP) monitoring and automating ventricular drainage of cerebrospinal fluid (CSF), focusing on its safety and potential to reduce complications associated with manual EVD manageme

In low-and middle-income countries, inadequate sanitation results in faecal contamination of the water used by urban farmers for irrigation. Consumers of raw contaminated vegetables run the risk of developing diarrhoeal diseases and helminth infections, which are a leading cause of under-five mortality and impact the well-being and productivity of millions of adults. This review identifies the evi

Introduction: Wearable sensors measuring bodily movements used in free-living conditions may help predict falls in older persons. Assessing their use in this context is essential to identify potential challenges related to fall risk screening. Therefore, this study aimed to assess the feasibility of conducting a prospective study comparing self-rated and wearable sensor-based measures for the asse

This contribution explores the evolution and determinants of public support for the euro since its creation in 1999 until the end of 2017, thereby covering the pre-crisis experience of the euro, the crisis years and the recent recovery. Using uniquely large macro and micro databases and applying up-to-date econometric techniques, the authors revisit the growing literature on public support for the

Objectives: An increased interest in the phenomenon and process of compassion, in both clinical and non-clinical psychological research, has been seen in recent decades. In these contexts, compassion is frequently understood as a felt response to the suffering of others that involves caring and seeing the universal nature of human suffering, as well as an authentic desire to ease the distress. Bas

Recent work has shown that 8-bit floating point (FP8) can be used for efficiently training neural networks with reduced computational overhead compared to training in FP32/FP16. In this work, we investigate the use of FP8 training in a federated learning context. This brings not only the usual benefits of FP8 which are desirable for on-device training at the edge, but also reduces client-servercom

Background: Mitochondrial respiration plays a central role in the survival of many eukaryotes, including apicomplexan parasites. A 479-bp fragment from the mitochondrial cytochrome b gene is widely used as a barcode to identify genetic lineages of avian malaria parasites Plasmodium and related haemosporidians. Here we looked for evidence of selection in the avian Plasmodium cyt b gene, using tests

The construction sector needs to transition toward using bio-based building materials in order to reduce its negative environmental impact. However, it is unclear how exactly such a bio-based future will look like, with different stakeholders in different geographical contexts having different visions of the sector’s future. Based on an extensive collection of expert interviews with stakeholders f