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Cancer immunotherapies activate the immune system to overcome tumor resistance and restore the antitumor immune response, however, excessive activation of the immune system may also affect normal tissues and organs and cause immune-related adverse events (irAEs) of varying severity. Current in vitro assays used for testing and predicting of irAEs induced by immunotherapeutics are associated with s
Using a microcontroller unit to implement different machine learning algorithms for myoelectric prosthesis control is currently feasible. Still there are hardware and timing constraints that need to be accounted for. This master thesis presents results from automatically generated Arduino code for some Neural Networks, Convolution Neural Networks and linear machine learning models that was impleme
Downstream processing is an essential part in the production of biomolecules and the optimization of these processes are of great value, since they can be both time consuming and expensive. One common type of enzyme used in different biotechnical approaches is proteases and in this study Protease X was investigated. In order to use the enzyme in a process, a purification procedure needs to be esta
This master thesis work consists of the development of new hardware and software for the control box of an azimuthal guidance system used by aircrafts during the approach to the runway. The thesis work was done at Safegate International AB as a project running along the usual development projects. When designing electronics to be used on an airfield there are a lot of regulations and standards t
Total resection of glioblastoma multiform (GBM), the most common and aggressive malignant brain tumor, continues to be a challenge. Achieving complete resection is limited by difficulty in intraoperative discrimination between normal and residual tumor cells. This project contributes to the development and evaluation of a fiber-optical based fluorescence/reflectance spectroscopy system as an intra
Ambiguity and controversy abounds the debate over the thousands of people trying to enter the European territory and their rights, especially in their procedural form. This paper explores the latest developments in the context of the European Court of Human Rights’ and the European Court of Justice’s expansive interpretation of the right to an effective remedy and the procedural guarantees afforde
Rhinosinusitis is the fifth most common diagnosis for which antibiotics are prescribed- but it is often done in vain. Currently, the only way to fully determine whether or not such treatment is actually needed is an invasive procedure. In order to spare patients from the discomfort that it would involve, this essential step is often skipped and instead, antibiotics are prescribed regardless. Using
Wind power developments in cold and icing conditions pose new challenges to the wind power industry. Icing of wind turbines cause safety hazards, production losses and increased loads. This means that there is a need to develop a technique to quantify the icing climatology and corresponding eects on wind turbines to enable large scale wind power developments in the windy, sparesly populated areas
This research proposes that an interdisciplinary approach to understanding the concept of culture and culture change could be beneficial for Sustainable Development. It explores the transferability of the DIKT Learning Model and theory of Creative Populations, originally found in management literature, and applies them to a social change corporation in Medellin, Colombia. The corporation analyzed
Design of a concrete column with biaxial moments and normal force is unpractical without the aid of a computer program. It is very time consuming to go through all calculations and to find a suitable layout of a cross-section and positioning of reinforcement for the final design. The goal of this thesis is to create a user friendly computer program for this problem. A critical pier in the Öland B
A 74-year mild hemophiliac with an inhibitor to factor VIII underwent five 2-L plasma immunoadsorption procedures with a Staphylococcal protein A (Prosorba) column over 7 days. Initially, the inhibitor level increased from 56 to 154 BU/mL. Serum immunoglobulins, immune complexes, C3 and C4 fell progressively with each procedure: C3a was increased. Before therapy, the patient had increased cytotoxi
These guidelines are a consensus work of a considerable number of members of the immunology and flow cytometry community. They provide the theory and key practical aspects of flow cytometry enabling immunologists to avoid the common errors that often undermine immunological data. Notably, there are comprehensive sections of all major immune cell types with helpful Tables detailing phenotypes in mu
BACKGROUND AND OBJECTIVE: Elderly patients are at high risk for medication errors in care transitions. The discharge summary aims to counteract drug-related problems due to insufficient information transfer in care transitions, hence the accuracy of its medication information is of utmost importance. The purpose of this study was to describe the medication discrepancy rate and associated risk fact
Both Sweden and Finland have education systems promoting equity and equality. However, recent societal and political changes linked to increased immigration have created new challenges in efforts to support linguistic diversity. This paper aims to explore how multilingualism is represented in the national compulsory school curricula in the two contexts, using the language orientation framework: la
Migration influx in Western countries resulting in increasingly diverse societies results in more complex situations for bureaucrats in their client interactions in welfare organizations. The role of discretion for services to clients has received much attention in the public administration research and therefore this study explores the relation among perceived workload, anti-immigration attitudes
OBJECTIVES: The present study validated data that had been reported to the Swedish Quality Registry for Cleft Lip and Palate (CLP) under new requirements from 2016, when use of the 5-year-old (5YO) and the Modified Huddart and Bodenham (MHB) indices for rating occlusion in children born with unilateral CLP (UCLP) was introduced. MATERIALS AND METHODS: The sample included blinded study casts (n = 9
Capillaroscopy is a non-invasive and safe tool which allows the evaluation of the morphology of the microcirculation. Since its recent incorporation in the 2013 American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) classification criteria for systemic sclerosis together with its assessed role to monitor disease progression, capillaroscopy became a ‘mainstream’ investiga
