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The aim of this work was to develop a pharmacokinetic model for the analysis of the pharmacokinetics of (111)Inlabeled monoclonal antibodies (mAbs) in B-cell lymphoma patients and to evaluate the model's ability to predict a subsequent radioimmunotherapy by (90)Y-labeled mAbs. Data from quantified scintillation camera images and blood samples were used to fit a compartment model. The modeling incl

Background: Relatives of people with a mental illness who live together can experience additional burdens that may require support. A Web-based tool including a psychoeducation module, a diary, and a password-protected forum was developed to support relatives of a person with depression. Objective: The objective of our study was to explore participants' use of the Web-based tool, with focus on the

Safety in density (SID) potentially explains the safety in numbers (SIN) phenomenon by positing that ‘the SIN effect can be reproduced simply through encouraging behaviour that leads to the formation of higher-density cyclist groups’. The study further explores this hypothesis using event-based exposure, queues and groups of road users. Using three different definitions of encounters between road u

The dynamics of ethanol production/consumption in baker's yeast were studied under feed- rate controlled conditions. The yeast was grown on molasses in an 8-l fed-batch reactor and experiments were done at cell concentrations between 5 and 65 g l−1. Small changes in the feed rate were made around a feed rate corresponding to the critical growth rate, at which the yeast cell metabolism switches bet

Objective: Varying degrees of inter-organizational collaboration concerning children at risk has grown rapidly since the 1980s. Collaboration is understood to provide a more holistic view of the child’s needs, lead to better care and treatment, more efficient law enforcement as well as increase knowledge in general. The aim of this presentation is to explore processes and effects, by highlighting

Using a system analysis approach compares different systems for handling and treatment of toilet waste and organic household waste. Design issues considered are source separation of urine, use of vacuum toilets and advanced nutrient recovery processes such as Reverse Osmosis (RO). All of the studied systems have low emissions of eutrophy ing compounds. Other environmental effects are mainly relate

Physical exercise is a potentially effective treatment for adolescents with mild to moderate depression. However, there is a lack of long-term follow-ups to reveal adolescents’ experiences of exercise as a treatment for depression. The salutogenic concept of sense of coherence (SOC), comprising the domains manageability, comprehensibility, and meaningfulness is important to understand behaviour ch

Participatory design (PD) has taken as its ideal that designers and users should engage in an equal language game. When we apply PD in contexts where some of the users involved are weak, ill, or have impairments, this assumed equality can no longer be an ideal. The workshop explores new ideals for participatory design in non-work settings with highly heterogeneous user constellations.