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Background: The global gene regulator Special AT-rich sequence-binding protein1 (SATB1) has been reported to reprogramme tumour cells into a more malignant phenotype and associate with poor clinical outcome in several cancer forms. In this study, we investigated the molecular correlates and prognostic impact of SATB1 expression in human epithelial ovarian cancer (EOC). Findings: Immunohistochemica
Two main topics are considered in this thesis: Machining with industrial robot manipulators and optimal motion control of robots and vehicles. The motivation for research on the first subject is the need for flexible and accurate production processes employing industrial robots as their main component. The challenge to overcome here is to achieve high-accuracy machining solutions, in spite of the
I avtal som ingås mellan kommersiella parter är det idag vanligt att skiljeförfarande väljs som tvistlösningsmetod. Det framhålls särskilt att det är en tvistlösningsmetod som bidrar till ett snabbt avgörande, ger parterna rätten att själva utse skiljemän samt att det är ett förfarande präglat av konfidentiellitet. Samtidigt brukar de kostnader som är förenade med skiljeförfarandet framhållas som Today, when commercial parties are contracting, it is common that they choose arbitration as their method of dispute resolution. In contrast to court proceedings, arbitration gives a quicker judgement, gives the parties the right to elect their arbitrators and is a process that is characterized by confidentiality. On the other hand, arbitration also comes with some disadvantages. One example, whic
Background: Periampullary adenocarcinomas are a heterogenous group of tumours with poor prognosis that hasnot improved considerably the last decades. Tumour morphology, i.e. intestinal type (I-type) or pancreatobiliarytype (PB-type), has been demonstrated to be a more relevant prognostic factor than anatomical origin. Tumourinfiltrating immune cells are vital in shaping the natural progress of canBackground: Periampullary adenocarcinomas are a heterogenous group of tumours with poor prognosis that hasnot improved considerably the last decades. Tumour morphology, i.e. intestinal type (I-type) or pancreatobiliarytype (PB-type), has been demonstrated to be a more relevant prognostic factor than anatomical origin. Tumourinfiltrating immune cells are vital in shaping the natural progress of can
As the competition between destinations grows, the need to stand out and offer memorable and unique experiences also grows. Culinary experiences and activities with elements of “the local” are a growing niche, which mirrors the trend of knowing where the food originates, and that it has been grown, produced, and transported in an ecologically, socially and culturally sustainable way. To be able as
Increase your salary | Akademikerföreningen at Scania and TRATON Hoppa till huvudinnehåll Join us Here's why We are members GDPR and how we process personal data Become a trustee Contact person Safety officer Member of the Board Member of the Election Committee Auditor Roadmap and initiatives Roadmap Work environment Salary, Benefits and Competence development Transformation Salary Increase your s
Title: The Unpacking of Female Managerial Life in Contemporary Organizations Authors: Annemijn Janien Bakker and Jana Marcie Wäller Supervisor: Stefan Sveningsson, Professor of Business Administration; Lund University School of Economics and Management, Sweden Date: 26th of May 2025 Purpose: The purpose of this research is to critically examine how leadership is constructed, experienced, and navig
Introduction – Hand-arm vibration syndrome (HAVS) is a chronic disease to vessels and nerves caused by vibrations. In Sweden, the medical check-up for vibrations (MCV) implements the EU surveillance system to detect early cases. No earlier research has shown participation in MCVs, nor why MCVs is avoided. We aimed to improve the understanding on avoidance of MCVs among vibration-exposed workers. M
Hard turning offers a cost-effective alternative to traditional grinding, yet the tool wear progression limits the broader industrial adoption. During hard turning, the surface microstructure of AISI 52100 steel transforms into a nanocrystalline structure known as white layer, accompanied by significant surface residual stresses. With optimal cutting conditions, surfaces develop nanocrystalline mi
Background: Induced resistance (IR) can be part of a sustainable plant protection strategy against important plant diseases. beta-aminobutyric acid (BABA) can induce resistance in a wide range of plants against several types of pathogens, including potato infected with Phytophthora infestans. However, the molecular mechanisms behind this are unclear and seem to be dependent on the system studied.
Chagas disease, also known as American Trypanosomiasis, is a parasitic infection caused by the triatomine bugs, commonly referred to as kissing bugs. It is the deadliest parasitic disease in South America but has spread beyond this region due to migration and climate change. Approximately 70 million people are at risk of infection, and there is no cure for the chronic phase of the disease. In prev
The construction of episodic memory is an automatic process. Event segmentation theory proposed that segmentation of the continuous perceptual stream into separate memory events occurs when changes in external boundaries lead to changes in internal perceptual and conceptual boundaries. The influence of perceptual and conceptual boundaries on episodic memory encoding has been the subject of intensi
Connecting science to political agenda-setting is essential for a sustainable transition and acceptable politics. This task is complicated by phenomena like post-truth, for which facts are a non-issue. However, post-truth is not the only issue. The practice of political spin, in which the significance of facts is reconstructed according to specific interests poses another threat to scientific cred
Målet med den här rapporten var att undersöka möjligheten att vidare rena spillvattnet på Dows anläggning i Landskrona. Dow tillverkar vattenbaserade bindemedel från akryl monomerer. Spillvattnet innehåller metalliska joner, såpor, restmonomerer och restpolymerer. Idag så renas spillvattnet med ultrafiltrering (UF) där permeatet släpps iväg till det kommunala reningsverket för vidare rening. EfterThe aim of this report was to investigate the possibility of further cleaning of the wastewater at Dow in Landskrona. Dow produces water based adhesives from acrylic monomers. The wastewater contains different metal ions, surfactants, residual monomers and polymers. The wastewater at Dow is treated with ultrafiltration (UF) which produces a permeate that is sent to the municipal waste water treatm
Asphalt is the most common material on the roads visible to our eyes. Asphalt occurs as both wearing coat and bearing coat. Asphalt consists of rock material in different grain sizes joined by a binder, bitumen, and eventually added additives. Bitumen is extracted from crude oil. Asphalt mastics is bitumen mixed with filler. Filler is stone material that completely passes a 0.074 mm sieve. Both bi
Nitrogen (N) cycle dynamics and N deposition play an important role in determining the terrestrial biosphere's carbon (C) balance. We assess global and biome-specific N deposition effects on C sequestration rates with the dynamic global vegetation model LPJ-GUESS. Modeled CN interactions are evaluated by comparing predictions of the C and CN version of the model with direct observations of C fluxe
Here we studied the effects of glial cell line-derived neurotrophic factor (GDNF) in a rat model that represents the symptomatic stages of Parkinson's disease. GDNF was infused starting 2 weeks after an intrastriatal 6-hydroxydopamine (6-OHDA) lesion in order to halt the ongoing degeneration of the nigrostriatal dopaminergic neurons. GDNF or vehicle was infused in the striatum or the lateral ventr
Background and Objectives. Mantle cell lymphoma (MCL) is an aggressive disease. Patients with this malignancy have a median survival of 3 years. To better understand disease progression, which is characterized by increased proliferation, we analyzed the gene expression of MCL with different proliferative indices, as determined by immunohistochemical staining for Ki-67. Furthermore, primary and rel
Purpose: To determine the reproducibility of quantitative susceptibility mapping at multiple sites on clinical and preclinical scanners (1.5 T, 3 T, 7 T, and 9.4 T) from different vendors (Siemens, GE, Philips, and Bruker) for standardization of multicenter studies. Methods: Seven phantoms distributed from the core site, each containing 5 compartments with gadolinium solutions with fixed concentra
Following Emily Wardill's exhibition "Matt Black and Rat" at Bergen Kunsthall, January 20th to March 26th 2017, the publication Things Keep Their Secrets, is an extensive and multi-faceted work which includes both images and stills from the artist's latest works, the unique fumages, manually inserted into each of the 750 copies – as well as two newly commissioned texts by philosopher Michael Marde
