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Background We designed the EURAMOS-1 trial to investigate whether intensified postoperative chemotherapy for patients whose tumour showed a poor response to preoperative chemotherapy (≥10% viable tumour) improved event-free survival in patients with high-grade osteosarcoma. Methods EURAMOS-1 was an open-label, international, phase 3 randomised, controlled trial. Consenting patients with newly diag
Deltidsanställning är vanligt förekommande inom branscher som vård, handel och service, där arbetskraftsbehovet ofta varierar. Samtidigt aktualiserar del-tidsarbete frågor om rättvisa och skydd mot diskriminering. Denna uppsats behandlar frågan om det är förenligt med diskrimineringsförbudet att inte utge samma tillägg vid mertidsarbete som vid övertidsarbete. Uppsatsen tar utgångspunkt i förbudetPart-time employment is common in sectors such as health care, retail and service, where the need of labour often varies. At the same time, part-time employment raises issues of fairness and protection against discrimination. This thesis addresses the question of whether it is compatible with the prohi-bition of discrimination to grant lower additional pay for part-time employees working extra hou
The last two decades have seen considerable advancements in biometric technology, and consequently its use as a surveillance measure during occupation. The increasingly invasive and omniscient nature of biometric surveillance technologies means they constitute a considerable infringement on the private sphere of occupied populations, and consequently an interference with their right to privacy. Th
In wireless communication, Zadoff-Chu (ZC) sequences are often used for synchronisation between transmitters and receivers due to their advantageous mathematical properties. They are extensively used in LTE and 5G systems, as well as for UAV communications and various other applications. Blind detection of ZC sequences, meaning that their structural parameters are unknown, has applications for sec
This study examines whether the take-back and resale programmes of leading global fast-fashion retailers deliver substantive circular change or instead represent means-ends decoupling. Drawing on means-ends decoupling and organisational legitimacy theory, it analyses the corporate sustainability reports of H&M Group, Fast Retailing, and Inditex across five consecutive fiscal years (FY2020–FY20
Aim: To provide a comprehensive description of the clinical features, biochemical characteristics, and outcomes of infants up to 90 days old with COVID-19. Moreover, to assess the severity of the disease and propose an effective management pathway. Methods: Retrospective single-center study spanning three years. Patient data includes age, sex, symptoms, comorbidities, blood and urine test results,
OBJECTIVE: To examine the prevalence and predictive factors for celiac disease (CD) after a diagnosis of type 1 diabetes (T1D) in children and adolescents, to improve the current screening guidelines.RESEARCH DESIGN AND METHODS: The association between sex, age at T1D diagnosis, HLA, and diabetes autoantibodies, and a diagnosis of CD was examined in 5,295 children with T1D from the Better Diabetes
Key performance indexes (KPIs) in various forms have always been used in one way or another in the production and processing of raw materials. The need for KPIs was accentuated with the advent of industrialism in the western world. The way and strategy of manufacturing industrial products has been divided into several so-called developmental transformations. Primarily after the depression of the 1
The growing complexity of signal processing algorithms and platforms poses significant challenges to design methods and implementation tools. High-level dataflow programs, such as those in MPEG's RVC-CAL language, provide abstraction and the opportunity for extensive design-space exploration, but they do raise the problem of efficient automatic synthesis to hardware and software. This paper presen
The growing demand for performance improvements of urban wastewater system operation coupled with the lack of instrumentation in most wastewater treatment plants motivates the need for non-linear observers to be used as virtual sensors for estimation and control of effluent quality. This paper is focused on the development of a general procedure for on-line monitoring of activated sludge processes
Fake canonizations are prevalent in the former communist countries wherein arts and culture in general may still function as propaganda weaponry at the hands of the sponsoring state. The public is almost eliminated from the process of canonization, as the publishing houses, art galleries, and cultural industries seldom survive and flourish from sales to a real public. As a rule, their rarefied pub
In this contribution, we suggest two proposals to achieve fast, real-time lane-keeping control for Autonomous Ground Vehicles (AGVs). The goal of lane-keeping is to orient and keep the vehicle within a given reference path using the front wheel steering angle as the control action for a specific longitudinal velocity. While nonlinear models can describe the lateral dynamics of the vehicle in an ac
BACKGROUND: Even though trust is placed at the central point in ensuring proper functioning of the health systems, studies remain scant on how it affects both the implementation and uptake of COVID-19 response measures in low- and middle-income countries such as Tanzania. This study, therefore, explored the role of trust in the implementation and uptake of recommended COVID-19 response measures in
Horseflies (Tabanidae) are polarotactic, being attracted to linearly polarized light when searching for water or host animals. Although it is well known that horseflies prefer sunlit dark and strongly polarizing hosts, the reason for this preference is unknown. According to our hypothesis, horseflies use their polarization sensitivity to look for targets with higher degrees of polarization in thei
BACKGROUND: Wrist disorders are common in force demanding industrial repetitive work. Visual assessment of force demands have a low reliability, instead surface electromyography (EMG) may be used as part of a risk assessment for work-related wrist disorders. For normalization of EMG recordings, a power grip (hand grip) is often used as maximal voluntary contraction (MVC) of the forearm extensor mu
Contact allergy (CA) is not uncommon in the population, including to various fragrance allergens. If not diagnosed correctly, allergic contact dermatitis (ACD) may ensue, because targeted allergen avoidance is not possible. The primary objective of the study is to estimate the prevalence of CA to seven fragrance materials in patients with suspected ACD across Europe. Based on the outcome, a conclu
