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Importance: Geographic atrophy (GA) is a progressing atrophy of the neuroretina with no treatment option. Background: Age-related malfunction of retinal microglia amplifies response towards age-related tissue stress in age-related macular degeneration. Here, we investigated monocyte CD200 expression – the circulating middleman negotiating retinal microglial activity – in a poorly understood subtyp
Previous in vitro and case–control studies have found an association between the insulin-like growth factor (IGF)-axis and bladder cancer risk. Circulating concentrations of IGF-I have also been found to be associated with an increased risk of several cancer types; however, the relationship between pre-diagnostic circulating IGF-I concentrations and bladder cancer has never been studied prospectiv
Objective: Cancer and its treatment in childhood and young adulthood can cause hypogonadism, leading to increased risk of long-term morbidity and mortality. The aim of this study was to evaluate the risk of presenting with biochemical signs of hypogonadism in testicular cancer survivors (TCS) and male childhood cancer survivors (CCS) in relation to the type of treatment given. Design: Case-control
Complexes trans-[PtRCl(SR‘2)2], where R = Ph, mesityl, and p-anisyl and R‘ = Me or Et, have been synthesized and their crystal and molecular structures determined. Crystals of trans-[PtPhCl(SEt2)2] (2) are triclinic (P1̄) with a = 10.112(6) Å, b = 13.158(2) Å, c = 14.714(5) Å, α = 102.48(2)°, β = 94.394(4)°, γ = 90.22(3)°, and Z = 4. Crystals of trans-[Pt(mesityl)Cl(SMe2)2] (4) are monoclinic (P21Complexes trans-[PtRCl(SR‘2)2], where R = Ph, mesityl, and p-anisyl and R‘ = Me or Et, have been synthesized and their crystal and molecular structures determined. Crystals of trans-[PtPhCl(SEt2)2] (2) are triclinic (P1̄) with a = 10.112(6) Å, b = 13.158(2) Å, c = 14.714(5) Å, α = 102.48(2)°, β = 94.394(4)°, γ = 90.22(3)°, and Z = 4. Crystals of trans-[Pt(mesityl)Cl(SMe2)2] (4) are monoclinic (P21
Background: New methods are needed for collecting data of in- and outpatients and for improving outpatient compliance after discharge. Mobile technologies, such as smartphone apps, have shown promising results, (eg, helping unwell people by offering support and resources). Screening for the condition, including comorbidities, is a vital part of psychiatric care. Comorbid conditions, especially in
The aim was to evaluate an early prototype of a personalised home lighting system comprising body-worn loggers, a mobile phone, and LED-based lighting with variable intensity and colour temperature. A convenience sample (N = 28, 50% female) wore the devices for 24 hours in the field and were given a demonstration of the lighting system components in a full-scale model of a studio apartment. Partic
Objective: Recent study showed high chemokine CXC ligand 5 (CXCL5) is thought to be associated with insulin resistance in humans. However, evidence from large-scale populations about the relationship between serum CXCL5 level and metabolic phenotypes is scarce. Here we sought to evaluate serum CXCL5 distribution and its association with metabolic phenotypes among middle-aged and older Chinese. Res
This dissertation explores how son preference is constructed and renegotiated in light of social change in the People’s Republic of China (PRC). Based on secondary sources and interviews with women and men in rural Anhui Province as well as key informants, it addresses son preference from conceptual, methodological, empirical and ideological perspectives. The analysis centres around son preference
This thesis deals with control of production at large-scale process industrial sites in the presence of disturbances. The main focus is on disturbances in the supply of utilities such as steam, cooling water and electricity. A general method for reducing the revenue loss due to disturbances in utilities is introduced, which may provide both proactive and reactive disturbance management strategies.
OBJECTIVE-This study assessed insulin and glucagon secretion in relation to insulin sensitivity in Caucasian women who develop impaired glucose tolerance (IGT) versus those who maintain normal glucose tolerance (NGT) over a 12-year period. RESEARCH DESIGN AND METHODS-At baseline and after 3, 8, and 12 years, glucose tolerance (75-g oral glucose tolerance test), insulin sensitivity (euglycemic-hype
The events of 9/11 and the subsequently launched ?war on terror? ushered in a new era of world politics. The new, global security agenda came to dominate international politics bringing about the securitization of a range of international policies. As a part of this process, international development cooperation has come to be increasingly articulated in the language of security as well, i.e. it h
The means to political participation at the local level in Sweden are changing and this change is analyzed through a case study. The first aim is to explore the forms of public political participation in Swedish municipal Älvkarleby, namely public question time in local government, citizen motions and open meetings. A part of this is also to analyze he every day contact between citizens and repres
This thesis addresses the right to education and its implementation. It briefly assesses the right to education while focussing on the right to primary education. The implementation of human rights as stated in international instruments can meet with hindrance in the form of cultural relativist arguments as well as resistance on pragmatic grounds. The case study carried out in Tanzania aims at ass
This thesis concerns the impact of instrumental benefits and norms on state behaviour in international relations. This is studied on the case of the EU’s and Japan’s initiation of enforcement against North Korea in the UN Human Rights Council, which has garnered increased attention since 2013 when a commission of inquiry successfully put the issue on the international community’s agenda. I ask w
Being acquainted with four of the most famous games in game theory, we will learn that players often are better paid off cooperating with each other, but that the structure of the game forces them to defect from cooperation. Only when confronted with the zero-sum game the players have no incentive to cooperate. In all the other games, cooperation is secured if the players commit themselves to adop
Detta examensarbete har gjorts I samarbete med Tylö AB, ett bastuföretag med säte i Halmstad. De hade behov av att utreda möjligheten att använda universella, gärna likadana, gångjärn på alla sina bastudörrar i glas. Idag används flera olika typer av gångjärn beroende på var dörren ska monteras och alla olika gångjärn kräver olika typer av bearbetning på glasdörren för att kunna monteras. Tylö vil
Termen konkurrens uppfattas ofta som mångtydig. Trots dess ansedda mångtydighet företar konkurrensrätten som rättsområde att skydda konkurrensen. Sällan förekommer diskussioner i den juridiska litteraturen gällande betydelsen av konkurrens. De definitioner som har angetts förefaller undermåliga i relation to ordets allmänna innebörd. Hur kan vi då ha sammanhållet rättsområde samt skydda konkurrensThe word competition is often regarded as being ambiguous. Despite the word’s ambiguity the field of competition law undertakes to protect competition. In the legal literature the definition of the meaning of the word is seldom discussed. When it is being defined, the definitions appear to be inadequate regarding the words meaning in everyday speech. How it is then possible to have a coherent area
