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A role for PKC-epsilon in Fc gamma R-mediated phagocytosis by RAW 264.7 cells

Protein kinase C (PKC) plays a prominent role in immune signaling, and the paradigms for isoform selective signaling are beginning to be elucidated. Real-time microscopy was combined with molecular and biochemical approaches to demonstrate a role for PKC-epsilon in Fcgamma receptor (FcgammaR)-dependent phagocytosis. RAW 264.7 macrophages were transfected with GFP-conjugated PKC isoforms, and GFP m

Functional Variants of Fc Gamma Receptor (FCGR2A) and FCGR3A Are Not Associated with Susceptibility to Systemic Sclerosis in a Large European Study (EUSTAR).

OBJECTIVE: To investigate the possible role of FCGR2A 519A>G and FCGR3A 559A>C functional polymorphisms in the genetic predisposition to susceptibility to systemic sclerosis (SSc) or clinical phenotype. METHODS: A total of 1566 patients with SSc and 2271 geographically matched controls were included in our study. We analyzed the genotype and allele frequencies of the FCGR2A 519A>G and FCGR3A 559A>

Recombinant factor IX Fc for the treatment of hemophilia B

Current hemophilia B treatment guidelines recommend routine prophylaxis with factor IX (FIX) replacement products, tailored to maintain plasma activity at levels that will prevent bleeds. However, plasma FIX activity may not be the primary determinant or best indicator of hemostatic efficacy due to its extravascular distribution. FIX replacement therapy has evolved to include extended half-life (E

Creativity and the evolvement of culture. The altering capacity of art works, paper presentation, Lisbon, 26-29 June.

Title:Creativity and the evolvement of culture. The altering capacity of art works.Creativity, in the sense finding original solutions to life world problems, can be seen as the principal force of cognitive and communicational genesis, such as when new verbal language elements occur (Heine/Kuteva 2007). Creativity has been defined as the original act that not only makes a radical “revision of a co

Cultural and public centres

On this page, you will find a selection of the University's public activities. These include music, museums, discovery centres and botanical gardens. Botanical GardenThe Botanical Garden cultivates thousands of plant species on eight hectares of land in central Lund. The Garden operates a wide variety of activities in the areas of botany, horticulture, plant preservation and environmental awarenes

https://www.lunduniversity.lu.se/about-university/visit-lund-university/cultural-and-public-centres - 2026-04-21