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Artros, vår vanligaste ledsjukdom, orsakar smärta och funktionsnedsättning och drabbar främst knä, höft och fingerleder. Dagens behandling är fokuserad på smärtlindring, sjukgymnastik och eventuell ledersättning. Vid ledskada och artros bryts broskproteiner ner, och ledskador är en riskfaktor för artros, men mekanismerna som leder fram till artros är till stor del okända. Vi studerar de molekyläraOsteoarthritis (OA), the most common joint disease, causes pain and disability and mainly affects the knee, hip and finger joints. Treatment focuses on pain relief, physical therapy and eventually prosthesis. Cartilage proteins are degraded after joint injuries and in OA; joint trauma is a risk factor for OA, but the mechanisms leading to OA are mainly unknown. We study the molecular and structura

1 ClimBEco course (3 ECTS credits) Biodiversity and ecosystem services: science and practice September 17-22, 2023; Kullaberg Nature Reserve, Kullaberg, Sweden Sunday 17.09: Arrival day 16:00 Pick-up at Lund Central Station (group transit via minibus) 18.00-18:30 Welcome and introduction 18.30-19:30 Dinner Monday 18.09: Linking biodiversity and ecosystem services across scales 8.00-9.00 Breakfast

https://www.cec.lu.se/sites/cec.lu.se/files/2023-06/ClimBEco_BES_course2023_schedule_public_0.pdf - 2026-04-25

The objective of this study was to develop a population pharmacokinetic–pharmacodynamic model of subcutaneously administered bupivacaine in a novel extended-release microparticle formulation for postoperative pain management. Bupivacaine was administered subcutaneously in the lower leg to 28 healthy male subjects in doses from 150 to 600 mg in a phase 1 randomized, placebo-controlled, double-blind

Supply chains are difficult to plan because they involve complex relationships that influence supply chain performance. In this paper, discrete-event simulation (DES) is discussed in order to identify if it could be a technique used to improve supply chain planning. Two DES models have been developed and are used in this paper to find out whether DES could be a technique for unraveling the complex

In most genres of fiction representations of a profession, discipline or calling must broadly resonate with the conceptions of that role held by audiences. But very few represenations of PR practice to be found in novels written by UK-based writers draw a picture of PR activity that sits comfortably with the ”idealised” models offered by organisations such as the Chartered Institute of Public Re

Gröna och förnybara energikällor har under åren sett ökad uppmärksamhet inom forskning och utveckling, där solceller har fått särskild uppmärksamhet. Solceller består av flera lager, eller komponenter, med olika funktioner och den här tesen fokuserar på material som bygger upp det aktiva lagret. Det aktiva lagret är det som absorberar solljus vilket exciterar elektroner till att bilda en elektriskThe interest in energy sources has shifted over the years toward sustainable energy, which has popularized the research in solar cells (among other energy sources). One of the key topics in solar cell research is the power conversion efficiency, and to understand how this can be improved one must understand the photo-induced dynamics of the solar cell material. In this thesis, we modeled the condu