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INTRODUCTION: Comprehensive geriatric assessment (CGA) is a multidimensional, interdisciplinary diagnostic process used to determine the medical, psychological and functional capabilities of frail older people. The primary aim of our current study is to confirm whether CGA-based outpatient care is superior than usual care in terms of health-related outcomes, resource use and costs.METHODS AND ANAL

Type 2 diabetes (T2D) is a common metabolic disease and its prevalence is increasing worldwide. Adipose tissue plays an important role in metabolic processes. Environmental factors may affect metabolic phenotypes and epigenetics may mediate this influence. We used Illumina 450k microarrays to study correlations between epigenetic patterns in human adipose tissue and environmental factors such as h

Antalet allvarliga konsekvenser av katastrofer i världen har ökat, vilket lett till ett internationellt initiativ för att främja utvecklingen av nationella strategier för katastrofriskreducering (DRR) och resiliens. Ett av de globala målen i Sendairamverket för katastrofriskreducering 2015-2030, antaget av FN:s medlemsstater, handlar om att länderna ska ta fram strategier kopplat till DRR (mål E).Increasing impacts from hazards worldwide, including Sweden, have prompted international efforts to promote the development of national strategies for disaster risk reduction (DRR) and resilience to reduce associated impacts and support sustainable development. The development of such strategies is global target E of the Sendai Framework for DRR 2015-2030, which was adopted in 2015 by Sweden and o

Popular Abstract in Swedish I avhandlingen presenteras en analys av den svenska rösträttsrörelsens diskursgemenskap mellan åren 1887 och 1902. Studien fokuserar huvudsakligen på rörelsens kärna; Sveriges allmänna rösträttsförbund. Denna organisation, ledd av en överstyrelse och ett verkställande utskott i Stockholm, fungerade som rörelsens nationella ramverk under perioden 1890-1900. TraditionelltThe People, the Axe and the Root of Injustice: the Swedish Suffrage Movement's Discourse Community 1887?1902, its Production of Meaning and the Concept of Democracy In this thesis, I present a study of the Swedish suffrage movement's discourse community. The analyses focus primarily on the core of this movement, the Swedish Public Suffrage Association (Sveriges allmänna rösträttsförbund). This as

Carbon sequestration is an essential ecosystem service (ES) for climate change mitigation. For reasons of simplicity this ES is often quantified considering carbon storage in four carbon pools: aboveground biomass, belowground biomass, dead organic matter and soil organic carbon. Indicators of these four pools are estimated by modelling, reference values, or field methods and data processing of di

Feedbacks from the climate to other components of the coupled human-Earth system are expected to strongly influence the co-evolution of human society and its environment. Representing these feedback loops between climate and society, via the Earth system's response to human activities and the subsequent effect back onto social systems, is essential in order to fully explore the dynamics of the cou

The use of celestial or geomagnetic orientation cues can lead migratory birds along different migration routes during the migratory journeys, e.g. great circle routes (approximate), geographic or magnetic loxodromes. Orientation cage experiments have indicated that migrating birds are capable of detecting magnetic compass information at high northern latitudes even at very steep angles of inclinat

In acts of memorialisation, the objects that ”help” people get into contact with (their memory of) the deceased – like gravestones, personal collections of the deceased’s paraphernalia, objects placed at sites of sudden death, etc. – are often strictly regulated, differently in different cultures. At ”wrong” spots in the urban environment for instance, memorial places can thus be regarded as highl

The objective of this paper is to report the effects that control/operational strategies may have on plant-wide phosphorus (P) transformations in wastewater treatment plants (WWTP). The development of a new set of biological (activated sludge, anaerobic digestion), physico-chemical (aqueous phase, precipitation, mass transfer) process models and model interfaces (between water and sludge line) wer

Popular Abstract in Undetermined Vårt immunförsvar består av molekyler, celler, och barriärer som har till uppgift att hålla oss friska genom att avlägsna eller stänga ute virus och skadliga mikroorganismer. På alla kärnförsedda celler i vår kropp sitter en stor mängd MHC klass I-molekyler, strukturer som kan liknas vid korgar. I varje korg ligger en peptid som är ett fragment av något som finns iHuman leukocyte antigen class I (HLA-I) molecules are present on all nucleated cells and present the cell content to cytotoxic T lymphocytes in the form of peptides. Maturation of HLA-I occurs in the endoplasmic reticulum and results in stable peptide-HLA-I complexes, in the presence of proper quality control. For proper peptide binding most HLA-I molecules interact with the peptide-loading comple

Popular Abstract in Swedish Kultursemiotiken studerar möten mellan kulturer. Begreppen Kultur, Extra-kultur och Icke-kultur utvecklades av Tartuskolan under 1970-talet, och användes i deras studier av den ryska kulturen och dess relation till Västeuropa. Särskild vikt lades vid Peter den Stores försök att göra Ryssland mer likt Väst. Målet med denna avhandling i kultursemiotik är att vidareutvecklCultural semiotics studies encounters between cultures. Notions such as Culture, Extra-culture and Non-culture were developed in the 1970s by the Tartu school and were used in their studies of Russian culture and its relation to Western Europe, with special focus on Peter the Great's attempt to Westernize Russia in the eighteenth century. The aim of this dissertation in cultural semiotics is to fu

Quick clay has a major impact on landslide risk and it is therefore of considerable interest to map its presence and extent. In Sweden, quick clay has been involved in most landslides in soft clay with serious consequences. The predominant method for detection of quick clay in Sweden has been to take undisturbed samples and to perform fall-cone tests on the clay in its undisturbed and remoulded st

Popular Abstract in Swedish Tunnelbygget genom Hallandsåsen har utvecklats på ett sådant sätt och fått sådana konsekvenser, att frågan hur projektet skall förstås och förklaras är viktig. Vill man studera vilka mekanismer i samhället som kan förhindra projektets förlopp eller dess konsekvenser, bör man först förstå projektet. Matthias Baiers bok handlar om hur man med normer kan förstå och beskrivIn 1992 Swedens biggest tunnelproject begun. Two 8.5 km tunnels should cross a big ridge in southern Sweden which was seen as an obstacle to a fast and efficient railway line connecting Oslo and Gothenburg with Malmö and Copenhagen. However, the project had to stop in 1997 due to environmental damages. With only a third of the tunnel accomplished, the project was also much delayed and had a heavy

Optical region spectra for a number of upper main sequence chemically peculiar (CP) stars have been observed to study singly and doubly ionized praseodymium and neodymium lines. In order to improve existing atomic data of these elements, laboratory measurements have been carried out with the Lund VUV Fourier Transform Spectrometer (FTS). From these measurements wavelengths and hyperfine structure

Quantitative fluorescence in situ hybridization (FISH) and the combination of FISH with microautoradiography (MAR) were used in order to study the long-term population dynamics (2.5 years) and the in situ physiology in two parallel activated sludge pilot systems with enhanced biological phosphorus removal (EBPR). The two systems received the same influent wastewater, but were differently operated

This thesis, consisting of six papers, concerns methods for probabilistic analysis of engineering structures. The work comprises evaluations of available methods, developments of new and improved methods, and applications of probabilistic analysis to engineering structures. Comparative calculations using methods representing different strategies for stochastic finite element analysis were carried

Climate change is exposing high-latitude systems to warming and a shift towards more shrub-dominated plant communities, resulting in increased leaf-litter inputs at the soil surface, and more labile root-derived organic matter (OM) input in the soil profile. Labile OM can stimulate the mineralization of soil organic matter (SOM); a phenomenon termed “priming.” In N-poor subarctic soils, it is hypo

Background: Intensive rehabilitation is one of the most important aspects of care for people with stroke, and there is evidence that it leads to better recovery and higher levels of independence. However, pressure on resources in government funded secondary and primary healthcare settings means that for many people with stroke, intense rehabilitation is not available. Effective and efficient ways

Modern molecular and radiopharmaceutical development has brought the promise of tumor-selective delivery of antibody-drug conjugates to tumor cells for the diagnosis and treatment of primary and disseminated tumor disease. The classical mode of discourse regarding targeted therapy has been that the antigen targeted must be highly and homogenously expressed in the tumor cell population, and at the