Filetype
CYLD is a deubiquitination enzyme that regulates different cellular processes, such as cell proliferation and cell survival. Mutation and loss of heterozygosity of the CYLD gene causes development of cylindromatosis, a benign tumour originating from the skin. Our study shows that CYLD expression is dramatically downregulated in basal cell carcinoma (BCC), the most common cancer in humans. Reduced
An experimental test system including the oil circulation system and the gas circuit system has been designed and built to explore the effects of the lubricating oil flow rate on the performance of a single-screw compressor, used in a portable natural gas liquefaction process. Outlet pressure, outlet volumetric flow rate, volumetric efficiency, and specific power rate are the parameters for evalua
In response to the challenge of socializing new IT employees, some IT departments are exploring the incorporation of enterprise social media (hereinafter ESM) as an informal organizational socialization tool. Because this is a relatively new phenomenon, little is known about how ESM facilitate employee socialization. In order to contribute to our understanding of how ESM affects employee socializa
We present a model for the concurrent formation of globular clusters (GCs) and supermassive stars (SMSs, ≳103M⊙) to address the origin of the HeCNONaMgAl abundance anomalies in GCs. GCs form in converging gas flows and accumulate low-angular momentum gas, which accretes on to protostars. This leads to an adiabatic contraction of the cluster and an increase of the stellar collision rate. A SMS can
Diesel engines are the most common engine technology used in transportation. Its widespread use comes from its inherent high efficiency and its relative low cost. It suffers from pollutant emission issues, however, that need detailed understanding of their origins to meet the strictest current and upcoming emission standards. The work presented in this thesis focuses on the study of the mechanism
Coordinated Multi Point (CoMP) transmission and reception techniques are used in order to improve the performance of single or multiple cells in wireless systems. A system using CoMP techniques is capable of jointly optimizing its transmission and/or reception and, hence, achieving higher performance. In this work, performance evaluation of three CoMP techniques are performed based on simulations
For more than 30 years since it was first proposed by Harrington et al., the Theory of Characteristic Mode (TCM) has only been applied to perfect electric conductors (PEC), and more recently lossless dielectric materials. One key challenge in computing the characteristic modes (CMs) of non-PEC materials using the PMCHWT surface integral equation is the presence of internal resonances in the soluti
Adaptive and multi-level governance is often called for in order to improve the management of complex issues such as the provision of natural resources and ecosystem services. In this case study, we analyse the contemporary multi-level governance system that manages water resources and its ecosystem services in a fresh water lake in Sweden. We assess the relative importance and barriers of three c
The most critical question for climate research is no longer about the problem, but about how to facilitate the transformative changes necessary to avoid catastrophic climate-induced change. Addressing this question, however, will require massive upscaling of research that can rapidly enhance learning about transformations. Ten essentials for guiding action-oriented transformation and energy resea
The physiological process of swallowing is not only a simple transfer of liquids or food boluses from the oral cavity to stomach, but also a complex succession of voluntary and involuntary phases that involve complex deformations and require the entire functionality of the oropharyngeal apparatus. When this functionality is affected, people experience dysphagia, which is described as a combination
Den här avhandlingen kombinerar vetenskapen om komplexa adaptiva system med ekonomiska geografi för att beskriva och undersöka självorganiserande principer och drag i täta urbana ekonomier, särskilt med avseende på flöden av information och kunskap mellan människor som ger upphov till produktivitetsrelaterade externaliteter. Avhandlingen består av en kappa som presenterar det övergripande ramverkeThis doctoral thesis combines complexity science and economic geography in order to explore bottom-up, self-organizing principles within urban economies, in particular in relation to the flow of information and knowledge between people. The thesis consists of a kappa that covers the general theoretical framework and four papers. The papers cover urban scaling and intra-urban scaling analysis, loca
BackgroundEven though the importance of a facilitator during an implementation process is well described, the facilitator’s role is rarely problematized in relation to the organizational context in terms of power and legitimacy; themes which have recently been brought to the fore when studying change in health care organizations. Therefore, in this article, we present a qualitative study with the
The article explores the degree to which memory studies has become established as an academic field. Although we acknowledge that there are drawbacks to formal institutionalization, we contend that it is useful to think strategically about the future of memory studies. We argue that three key developments must take place in order for a field to become institutionalized. First, individual scholars
This brief presents an on-chip memory subsystem for massive multiple-input-multiple-output (MIMO) baseband processing at the base station. In massive MIMO systems, the required memory bandwidth and capacity are orders of magnitude higher than those used in conventional wireless systems, due to the large number of serving antennas. These are further combined with design targets on low access latenc
Reflection in EEG parameters of the process of solving two types of mental tasks, i.e. spatial-imaginary and verbal-logical, was investigated in nine test-subjects. Mental efforts were found to specify EEG spatiofrequency patterns depending on the task type and subject's identity. These patterns were unique and reproducible enough to enable identification of this or the other type of mental task w
