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Aims: Alexithymia has been linked to cardiovascular disease. The aim was to explore whether the immuno-inflammatory variables galectin-3 binding protein (Gal3BP), soluble (s)CD163 and galectin-3 were independently associated with alexithymia, while controlling for known risk factors for cardiovascular disease, such as depression, anxiety, impaired glycemic control, obesity, smoking, and physical i

Introduction: Limited prospective evidence is available to guide selection of first-line maintenance therapy in patients with COPD. This pre-specified analysis of the EMAX trial explored the efficacy and safety of dual-versus mono-bronchodilator therapy in maintenance-naïve and maintenance-treated patients. Methods: The 24-week EMAX trial evaluated lung function, symptoms (including rescue medicat

The transition from a reliance on fossil resources to the use of renewables for the production of energy, fuels and chemicals is essential for ensuring the sustainability of continued human development. Plant-based biomass is a renewable resource which can be transformed into all of these products. However, biomass is a heterogeneous material composed of several fractions with different chemical p

Background: Violence due to firearms is a major global public health issue and vascular injuries from firearms are particularly lethal. The aim of this study was to analyse population-based epidemiology of firearm-related vascular injuries. Methods: This was a retrospective nationwide epidemiological study including all patients with firearm injuries from the national Swedish Trauma Registry (SweT

BackgroundIn primary health care people with mental health needs are often overlooked or masked with physical complaints. It has been suggested that public health nurses lack sufficient knowledge when encountering people with mental health problems. Low levels of mental health literacy among professionals are associated with negative patient outcome. There is a need to understand public health nur

The genetics of β-cell function (BCF) offer valuable insights into the aetiology of type 2 diabetes (T2D)1,2. Previous studies have expanded the catalogue of BCF genetic associations through candidate gene studies3–7, large-scale genome-wide association studies (GWAS) of fasting BCF8,9 or functional islet studies on T2D risk variants10–14. Nonetheless, GWAS focused on BCF traits derived from oral

Background and Objectives Structural brain MRI and blood-based phosphorylated tau (p-tau) measures are among the least invasive and least expensive Alzheimer's disease (AD) biomarkers to date. The extent to which these biomarkersmay outperformone another in predicting future Alzheimer dementia diagnosis is poorly understood, however. This study investigated 2 specific AD biomarkers, i.e., a cortic

A new principle for mainstream nitrogen removal through nitritation followed by anammox was studied in a two-stage moving bed biofilm reactor (MBBR) configuration. The first stage was optimized for nitritation by using thin biofilms and a feed alternating between synthetic mainstream wastewater at 15°C and, for shorter periods, synthetic reject water at 30 °C. The exposure of the biofilm to reject

Both studies on animals and humans have demonstrated the role of inflammatory mediators on the retinopathy process.2,3 Dexamethasone is a glucocorticoid with a known reductive effect on several of these mediators and on the expression of VEGF.4Starting in 2016, infants receiving laser ablation for type 1 ROP at Skåne University Hospital were administered dexamethasone eye-drops postoperatively, us

Core-shell nanoparticles have gathered much attention of the scientific community owing to their potential applications in various fields including biomedical imaging and catalysis. Predicting core-shell preference1-3 is, however, still largely based on a few experimental observations and limited theorical studies, and hence development of new core-shell nanoparticles is normally built on a trial-

Introduction The potential impact of socio-economic condition on virological suppression during antiretroviral treatment (ART) in sub-Saharan Africa is largely unknown. In this case-control study, we compared socio-economic factors among Ethiopian ART recipients with lack of virological suppression to those with undetectable viral load (VL). Methods Cases (VL>1000 copies/ml) and controls (VL<150 c

Climate change and its associated challenges may have an impact on people and communities. Studies provide conceptual and empirical insight of the relationship between social capital and resilience. However, the social dimensions of resilience have received little attention in climate change research. This short article provides a rapid review of published studies that investigate the social dimen

IntroductionAn important hallmark of cancer is escaping the immune system. Despite advances in immunotherapy, only a subset of patients experiences clinical benefits. It was shown that adoptive T cell or checkpoint inhibition therapy rely on the presence of conventional dendritic cells type 1 (cDC1). cDC1 excel in recruiting and priming protective CD8+ T cells through cross-presentation. However,

BACKGROUND: There has been a growing body of evidence associating consumption of ultra-processed foods (UPF) with adverse health outcomes including depression, cardiovascular disease, all-cause mortality. However, whether UPF are associated with dementia is unknown. The authors investigated the associations between UPF and dementia incidence in UK biobank.METHODS: We included 72,083 participants (

Varje år sker det tusentals olyckor i trafiken i Sverige till följd av det stora transportbehovet i samhället. Transportstyrelsen har ett mål, Nollvisionen, som innebär att ingen ska dödas eller skadas allvarligt i trafiken. För att nå målet är en åtgärd att hastigheten sänks där gång- och cykeltrafik behöver interagera med motorfordon. Det kan man göra i form av sidoförskjutningar, avsmalning av Every year, thousands of traffic accidents occur in Sweden as a result of the transportation need in society. The Swedish Transport Agency has a goal, Vision Zero, which means that no one should die or be severely injured in traffic. To reach the goal one measure is to reduce the speed where pedestrians and cyclists need to interact with motor vehicles. This can be done by chicanes, narrowing of t

Predictive archaeological modelling is a complex analytical process that requires the understanding of how complex environmental and anthropogenic spatial phenomena relate to the selection of archaeological site location and knowledge of the requirements and potential biases inherent in the method of modelling and the raw data itself. This paper aims to demonstrate the utility of the weights of ev

Green entrepreneurship – technological eco–innovations and ecopreneurs’ acts – has recently received much attention from European policymakers as one promising response to the challenges of sustainable economic development due to its potential to catalyze and build a low–carbon or green economy. This topical relationship between green entrepreneurship and sustainable economy has also gained increa

Risk measures such as Value at Risk are highly dependent on a sample of daily returns. The daily return can be measured in different intervals and this thesis examines how the choice of the daily return interval affects derivative pricing, risk measures, fund performance and products with collateral agreements. It is shown that the VaR measure varies significantly with the choice of daily return i

Den tekniska utvecklingen innebär att det finns nya sätt att kränka en annan person som inte överensstämmer med de tillvägagångssätt som tidigare avsetts i svensk straffrätt. Förevarande uppsats är en undersökning av straffbara ofredanden på sociala medier. Utredningen görs med utgångspunkt i den kritik som riktats mot svensk lagstiftning. Två bestämmelser som kan aktualiseras när brott begås via Due to the technical development, new ways of violating another person has been created. These ways do not comply with the procedures previously set out in Swedish penal law. This essay is an investigation of criminal offenses carried out on social media. The research is based on the criticism raised towards Swedish legislation. Focus lies on two provisions, molestation and sexual molestation acco