Search results

Excitatory amino acids are implicated in the development of neuronal cell damage following periods of reversible cerebral ischemia or insulin-induced hypoglycemic coma. To explore the importance of glutamate receptor activation in the posthypoglycemic phase, we exposed rats to 20 min of insulin-induced severe hypoglycemia. The rats were treated immediately after the hypoglycemic insult with four r

Objective: Around 30% of people with schizophrenia are refractory to antipsychotic treatment (treatment-resistant schizophrenia). Abnormal structural neuroimaging findings, in particular volume and thickness reductions, are often described in schizophrenia. Novel biomarkers of active brain pathology such as neurofilament light chain protein are now expected to improve current understanding of psyc

Spatial (memory) update strategies depend on situational factors, such as availability of external information, familiarity with the environment, and cognitive demand. Of key interest to this research is the multimodal integration of environmental and individual characteristics in visuospatial update and reorientation in situations of extensive (embodied) rotational locomotion in naturalistic cond

Informed by queer life practices, theories, and affinities, this documented artistic research project (doctoral thesis) draws from new materialist and post-humanist discourse in order to reconsider what role visual media play in the historical need to separate the human and the environmental. It asks, how do we challenge prevailing perceptions of film and photography as inexorably linked to ideas

We have examined whether in vivo exposure to the glutamate analogue, kainic acid, induces cell loss through apoptosis and/or through necrosis. The vulnerability of rabbit retinal cells was evaluated by routine histopathology. The DNA fragmentation was examined using an in situ method (TUNEL: TdT-mediated biotin-dUTP nick-end labelling) and agarose gel electrophoresis of extracted retinal DNA. Reti

Abstract in Norwegian Bakgrunn. Fallulykker er et viktig helseproblem hos eldre. Både balansetesting og registrering av egenrapportert funksjon kan være måter å forutse fremtidige ulykker på. Materiale og metode. I en kohortstudie ble egenrapportert gangfunksjon kartlagt hos 307 tilfeldig utvalgte hjemmeboende kvinner 75 år og eldre. Kvinnene gjennomgikk også testing av balanse og gangfunksjon, oBACKGROUND: Falls represent an important health problem among the elderly. Balance testing as well as registration of self-reported balance problems may be appropriate in order to predict the risk of future falls. MATERIALS AND METHODS: Self-reported walking was assessed in 307 randomly selected women 75 years or older living at home. The women underwent testing of gait and balance and were follow

Popular Abstract in English According to the International Diabetes Federation (IDF), 415 million people suffer from diabetes worldwide. Diabetes occurs when the pancreatic beta cells are no longer able to produce or properly use insulin. Insulin regulates blood glucose levels by enabling glucose uptake into cells, providing the body with energy. Elevated glucose levels cause damages to highly vasDiabetes mellitus is metabolic disorder caused by a defect or lack of beta cell-produced insulin that controls blood glucose homeostasis. In addition to glucose, insulin secretion is regulated by the autonomic nervous system (ANS); the neurotransmitter acetylcholine as well as monoamines, such as dopamine, serotonin, melatonin and norepinephrine. Using a MafA mutant mouse model, we show that MafA

Insectivore classification has been one of the most controversial problems in mammalian systematics. Evolutionary relationships among the six extant families, Talpidae (moles), Soricidae (shrews), Erinaceidae (hedgehogs), Tenrecidae (tenrecs), Chryosochloridae (golden moles), and Solenodontidae (solenodons), have remained uncertain based on morphological data. Animals classified within the order L

The Swedish Air Navigation Service Provider, Luftfartsverket, together with Stockholm-Arlanda airport are implementing a new socio-technical concept called collaborative decision making. New technology and work procedures in collaborative decision making are directly affecting all organizations in an airplane turn-round process, and indirectly affecting legislators, authorities, suppliers, and pas

Popular Abstract in Swedish Denna avhandling behandlar modellsystem för farmaka som har DNA och RNA som mål i cellen. Framförallt behandlar den hur strukturen hos DNA och RNA påverkas av inbindning av olika substanser, samt hur fort denna inbindning sker. Tre olika typer av farmaka behandlas: 1. Platinaföreningar som länge använts som cytostatika, 2. RNA interferens som främst har utvecklats undDrugs targeting nucleic acids were studied in DNA and RNA model systems. The effects were investigated with respect to structural and thermodynamic influence, kinetics, and biological function. The drugs employed in this thesis were anticancer active platinum(II) complexes, polyamine derivatives, and siRNA. Structural changes were determined by use of chemical probing and circular dichroism (CD),

The oxides that form during thermal oxidation of natural FeS2 (pyrite and marcasite) consist of nanometer-sized crystals of alpha-Fe2O3 and gamma-Fe2O3. This is shown with heating experiments that were made up to 650 degrees C, which resembles temperatures used in metallurgical processes. It is shown that magnetic measurements can play a key role in the investigation of this reaction, due to the u

Joseph Beuys. Fat and felt. A critical essay. The extremely singular materials fat and felt for use in art, have an entirely dominating role in a long series of Joseph Beuys’ (1921-1986) most important work. They are found both in single works of art as well as in installations and happenings from the beginning of the 1960s and up to the end of the artist’s life. This essay deals with the artist’

This study documents the advancement of laying dates in three species of tits (Paridae) in southernmost Sweden during recent decades, and the absence of a similar response in the pied flycatcher Ficedula hypoleuca. It is based on several different nestbox studies; the oldest one starting in 1969. During 1969 to 2012, mean spring temperatures in the study area increased by between 0.06 and 0.08 °C This study documents the advancement of laying dates in three species of tits (Paridae) in southernmost Sweden during recent decades, and the absence of a similar response in the pied flycatcher Ficedula hypoleuca. It is based on several different nestbox studies; the oldest one starting in 1969. During 1969 to 2012, mean spring temperatures in the study area increased by between 0.06 and 0.08°C p

This Thesis seeks to give its reader the tools to understand the data privacy divide between the EU and the US. It explains the crucial notions, historical and jurisprudential factors and regulatory frameworks underlying and constituting it. First, it answers why regulating data privacy is paramount to our democratic societies on both sides of the Atlantic. The growing importance of the data dri

Vid domstolens avgörande av vårdnads- och boendefrågan kan beslut fattas antingen om att vårdnaden ska anförtros föräldrarna gemensamt eller en av föräldrarna samt om barnet ska bo växelvis hos båda föräldrarna eller stadigvarande hos en av dem. Bedömning ska alltid göras i varje enskilt fall och avgörande är vad som är barnets bästa, vilket stadgas i portalparagrafen i 6 kap. 2 a § föräldrabalkenIn the court’s judgement in matters of custody and residency of a child, decisions can be made to either entrust custody to both parents or one of the parents, and whether the child is to live alternately with both parents or permanently with one of them. The assessment is always to be made in each separate case with the best interest of the child, which is stipulated in chapter 6, section 2 a of

Uppsatsen behandlar konflikten mellan två inte sällan kolliderande intressen, vindkraft och rennäring. I ljuset av folkrättsliga instrument till skydd för urfolk, ska samernas rätt till mark och vatten skyddas. För samer är denna rätt en förutsättning för renskötselns bedrivande, som det samiska kulturarvet i stora delar bygger på. Rennäringen förutsätter stora markområden där renar fritt kan flytThis essay discusses the conflict between wind power and reindeer husbandry, two interests which at times collide. In light of international law and its instruments for the protection of indigenous peoples, the Samis’ rights to land and water shall be protected. The right to land is a prerequisite for the Samis to pursue their reindeer herding, which lays the foundation for the cultural heritage o

En huvudprincip i den svenska rättsordningen är att den förlorande parten i ett tvistemål ska ersätta den vinnande parten för dennes rättegångskostnader. Ersättningen till den vinnande parten ska i enlighet med 18 kap. 8 § rättegångsbalken (1942:740), fullt motsvara kostnaderna för processföringen, såvitt kostnaderna skäligen varit påkallade för tillvaratagande av partens rätt. Inom ramen för partAn essential rule in Swedish law is that the losing party in a litigation shall reimburse all costs incurred by the winning party. Section 8 in Chapter 18 of the Swedish Code of Judicial Proceedings (1942:740) concludes that “compensation for litigation costs shall fully cover the costs of preparation for trial […] to the extent that the costs were reasonably incurred to safeguard the party's

Barn som är under 15 år kan inte straffas i svensk rätt enligt 1 kap. 6 § brottsbalken (BrB) och därmed kan de inte heller bli föremål för rättsväsendets åtgärder p.g.a. brott. När samhällsåtgärder därmed måste tas, ligger ansvaret på socialtjänsten. Begår ett barn ett brott kan det ändå utredas av polis och åklagare genom stöd av lagen om unga lagöverträdare (LUL), en s.k. 31 § LUL-utredning. SChildren under the age of 15 can commit crimes but they cannot be punished under Swedish law in accordance with Chapter 1, Section 6 of the Criminal Code and therefore they cannot be subject to a preliminary criminal investigation by a Prosecutor or the Police. Instead, when children have committed a crime other societal measures can be taken. The responsibility for the care for these children lie

Den första oktober 2019 infördes med SFS 2019:523 en lång rad lagändringar i hyreslagen. Till de viktigaste ändringarna hör 1) kriminalisering av köpare av hyreskontrakt, 2) skärpta straff för försäljning av hyreskontrakt, 3) kriminalisering av andrahandsuthyrning om hyresgästen både saknar tillstånd från hyresvärd eller hyresnämnd och tar ut ett överpris och 4) att hyresrätter inte längre kan bytOn 1 October 2019 SFS 2019:523 was entered into action, containing a long list of legal changes in the Swedish Rent Act (Hyreslagen). Among the more prominent changes were i) the criminalization of buyers of a rental contract, ii) harsher punishment for selling such contracts, iii) criminalization of tenants who both sublet the apartment without permission from the landlord or the Rental Board and

Vulnerability to climate change and the capacity to adapt to it are the result of intersecting power structures, system dynamics, and social identity markers otherwise known as intersectionality; and thus, differ greatly between contexts. However, despite the stark contextual differences between small and metropolitan cities, and lower and higher income countries, the policy and study of climate c