Filetype
Objective: Patient-specific virtual reality (VR) simulation of cochlear implant (CI) surgery potentially enables preoperative rehearsal and planning. We aim to gather supporting validity evidence for patient-specific simulation through the analysis of virtual performance and comparison with postoperative imaging. Methods: Prospective, multi-institutional study. Pre- and postoperative cone-beam CT
Den boreala regionen innehåller 40% av jordens kol (C) som lagras i vegetation och mark med sina skogar som står för nästan 30% av den terrestra C sänkan. Boreala skogar upplever några av de snabbaste hastigheterna för klimatuppvärmning och ökningar i brandaktivitet, vilket hotar att släppa ut stora mängder av deras C reserver till atmosfären. Även om klimat och skogsbränder har stark kontroll öveThe boreal region contains 40% of the earth’s carbon (C) that is stored in vegetation and soils with its forests accounting for almost 30% of the terrestrial C sink. Boreal forests are experiencing some of the most rapid rates of climatic warming and increases in fire activity, threatening to release large amounts of their dense C reserves to the atmosphere. While climate and wildfire place strong
Aims. DE Boo is a unique system, with an edge-on view through the debris disk around the star. The disk, which is analogous to the Kuiper belt in the Solar System, was reported to extend from 74 to 84 AU from the central star. The high photometric precision of the Characterising Exoplanet Satellite (CHEOPS) provided an exceptional opportunity to observe small variations in the light curve due to t
Research on microplastics in Latin America is limited compared to a global perspective. Brazil plays a significant role in this context, as it possesses 12% of the world’s freshwater reserves, constituting 53% of South America’s water resources. There has been growing concern regarding the plastic pollution of the country’s freshwater systems in recent years. Therefore, this study investigated the
Introduction: We have previously adapted a clinical linear accelerator (Elekta Precise, Elekta AB) for ultra-high dose rate (UHDR) electron delivery. To enhance reliability in future clinical FLASH radiotherapy trials, the aim of this study was to introduce and evaluate an upgraded beam control system and beam tuning process for safe and precise UHDR delivery. Materials and Methods: The beam contr
In celiac disease, intestinal transglutaminase (TG2) produces immunogenic peptides by deamidation of gluten proteins. These products drive the celiac immune response. We have previously identified an interaction between gliadin and a food additive, E304i, which prevents gliadin processing (both deamidation and transamidation) by TG2, in vitro. In this study, we investigated if E304i could prevent
Network Data Analytics Function (NWDAF) is a key component in 5G networks, introduced by 3G Partnership Project (3GPP) standards, that leverages machine learning to optimize network performance. The 3GPP standards mandate that mobile network operators should retrain NWDAF models to maintain accuracy. However, the presence of adversarial user equipment (UE) can introduce corrupted data points durin
Although many efforts have been made to eliminate barriers in public transport worldwide, research shows that public transport is still often perceived as challenging, inconvenient, and inaccessible for many people with disabilities. A growing body of research points to several issues, relating to the spatial and temporal distribution of public transport, affordability, safety, and social barriers
The Älvkarleby test dam, constructed in Sweden, was designed with several intentionally created defects to serve as a controlled environment for evaluating various monitoring techniques. Among these, a unique three-dimensional (3D) Electrical Resistivity Tomography (ERT) setup was implemented. The ERT survey design, combined with full 3D calculation of the geometric factor and inversion constraine
Objective: Previously proposed “synchronous EEG patterns” predict poor outcome within 24 h after cardiac arrest (CA). We investigate the prognostic performance of these early EEG predictors in addition to the late EEG predictors (>24 h) recommended in the European post-resuscitation guidelines. Methods: Observational substudy of the TTM2-trial including consecutive comatose resuscitated patients.
The Viking Age (c. 800 – c. 1050 AD) was a period of dramatic change and transformative encounters across Europe and the wider world. Ships, seafarers, and the sea were central to these developments but, paradoxically, the Viking Age is generally studied through evidence and approaches on land. This has consistently hindered scholarly understanding of the maritime dimensions of the Viking Age; sur
Papain-like protease (PLpro) of SARS-CoV-2 is a vital enzyme involved in viral polyprotein processing and in the suppression of host immune response. Due to its strategic role in viral replication and pathogenesis, PLpro represents a valid yet challenging target for drug development. Fragment-based drug discovery (FBDD) is a powerful strategy employed by the FragMAX facility at MAX IV to identify
Introduction: Vulvar cancer may cause serious local symptoms that may impact negatively on the woman's health-related quality of life (HRQOL). However, knowledge about the prevalence of vulvar and lymphedema symptoms at diagnosis and during follow-up is limited. The aim of this study was to evaluate the longitudinal development of vulvar and lymphedema symptoms as well as the trajectory of HRQOL i
Observations of polarization position angle (θ) standards made from 2014 to 2023 with the High Precision Polarimetric Instrument (HIPPI) and other HIPPI-class polarimeters in both hemispheres are used to investigate their variability. Multiband data were first used to thoroughly recalibrate the instrument performance by bench-marking against carefully selected literature data. A novel co-ordinate
This chapter reviews polarization vision in diverse crustaceans with a specific focus on work completed since the 2014 edition of this book. Almost all crustaceans are sensitive to the planar polarization of light. They commonly possess two channels of orthogonally arranged photoreceptors with intrinsically polarization-sensitive ordered microvilli. These two channels are compared to impart linear
Future wireless systems are envisioned to be able to deliver ultra-reliable and low-latency communication.The third generation partner project (3GPP) has identified three different usage scenarios such as enhanced mobile broadband, massive machine-type communication, and ultra-reliable low latency communication.In each of those scenarios, several services and applications can be implemented, e.g.
Background: Branched-chain amino acids (BCAAs, isoleucine, leucine, and valine) are commonly applied to promote muscle protein synthesis. However, the effects of BCAAs on exercise-induced substrate metabolism, performance and post-exercise fatigue during endurance exercise remain unclear. Methods: In a double-blind cross-over design, eleven active males completed 1 h of constant load exercise (CLE
Adaptive plasticity processes are required involving neurons as well as non-neuronal cells to recover lost brain functions after an ischemic stroke. Recent studies show that gamma-Aminobutyric acid (GABA) has profound effects on glial and immune cell functions in addition to its inhibitory actions on neuronal circuits in the post-ischemic brain. Here, we provide an overview of how GABAergic neurot
Purpose Radiotherapy reduces the absolute risk of breast cancer mortality by a few percentage points in suitable women but can cause a second cancer or heart disease decades later. We estimated the absolute long-term risks of modern breast cancer radiotherapy. Methods First, a systematic literature review was performed of lung and heart doses in breast cancer regimens published during 2010 to 2015
Disadvantaged areas may prompt or force older people to relocate due to a lack of services, the presence of crime, and area unattractiveness, but knowledge in this area is insufficient. The aim was to investigate whether older adults living in different types of disadvantaged areas in Sweden were considering moving away from the area, and to explore similarities and differences in underlying resid
