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Objective: We studied a cohort of patients with nonsyndromic complete atrioventricular septal defect with and without concomitant complex cardiac anatomy and compared the outcomes after surgical repair. Methods: Between 1993 and 2018, 62 nonsyndromic patients underwent complete atrioventricular septal defect repair. Sixteen patients (26%) had complex complete atrioventricular septal defect with va

Background and purpose — Reported revision rates due to dislocation after hemiarthroplasty span a wide range. Dislocations treated with closed reduction are rarely reported despite the fact that they can be expected to constitute most of the dislocations that occur. We aimed to describe the total dislocation rate on the national level, and to identify risk factors for dislocation. Patients and met

Background: A dysregulated postprandial metabolic response is a risk factor for chronic diseases, including type 2 diabetes mellitus (T2DM). The plasma protein N-glycome is implicated in both lipid metabolism and T2DM risk. Hence, we first investigate the relationship between the N-glycome and postprandial metabolism and then explore the mediatory role of the plasma N-glycome in the relationship b

3D property formation has become an important solution to provide a more comprehensive and accurate representation of the property's physical characteristics than traditional 2D property formation. Despite the numerous benefits of the 3D property formation, there is a need for more detailed descriptions of 3D cadastral data delivery between the involved actors to ensure efficient and effective col

One of the biggest challenges parties in multiparty governments face is making policies together and overcoming the risk of a policy stalemate. Scholars have devoted much attention to the study of how various institutions in cabinet and parliament help coalition parties with conflicting policy preferences to be efficient in the policy-making process. Coalition agreements are one of many instrument

This thesis examines the role of beamlines with publication metadata from the European Synchrotron Radiation Facility (ESRF a large scientific facility offering diverse conditions for scientific research. As a user-oriented Big Science facility, the ESRF channels extremely brilliant light into different experimental areas called beamlines that house specific instruments that cater to the needs of

An association between high Galectin-4 (Gal-4) and prevalence of diabetes in subjects with heart failure (HF) has previously been reported. The purpose of this study was to confirm these findings, as well as to further investigate this association, in a Swedish HF population. In addition, a second aim was to explore Gal-4’s association with obesity and biomarkers of metabolism and heart failure. G

Deltas play a critical role in the ambition to achieve global sustainable development given their relatively large shares in population and productive croplands, as well as their precarious low-lying position between upstream river basin development and rising seas. The large pressures on these systems risk undermining the persistence of delta societies, economies, and ecosystems. We analyse possi

Background: Synaptic dysfunction and degeneration are central contributors to the pathogenesis and progression of parkinsonian disorders. Therefore, identification and validation of biomarkers reflecting pathological synaptic alterations are greatly needed and could be used in prognostic assessment and to monitor treatment effects. Objective: To explore candidate biomarkers of synaptic dysfunction

Context and Objective: Metabolic and body compositional consequences of GH deficiency (GHD) in adults are associated with a phenotype similar to the metabolic syndrome (MetS). Patients: We assessed MetS prevalence in adult GHD patients (n = 2531) enrolled in the Hypopituitary Control and Complications Study. Prevalence was assessed at baseline and after 3 yr of GH replacement in a subset of 346 ad

OBJECTIVES: Testicular germ-cell cancer (TGCC) patients are at risk of developing hypogonadism but no risk factors have yet been defined. METHODS: Blood was collected from 143 TGCC patients (after orchidectomy, prior to further therapy (T0) and 6, 12, 24, 36 and 60 months (T6, T12, T24, T36 and T60) after therapy). Biological hypogonadism (BH) was defined as: serum testosterone below 10 nmol/l and

A method for determination of the accessible volume fraction in gels as function of the molecular weight of the solutes is presented. The pore-size distribution is determined by measuring the rate of diffusion of a mixture of solutes into a gel using gel filtration for separation. The solutes, of various sizes, are detected by refractive index measurements. Two marker molecules (blue dextran and g

Background: Turner syndrome (TS) is a complex genetic disorder with raised mortality. Our objective was to investigate mortality and causes of death in TS. Methods: A matched retrospective observational study of women with TS recruited from the Turner centers in Sweden were conducted. A total of 472 women with TS, ≥16 years old with a cytogenetically verified diagnosis and 2357 controls, matched f

The separation of multiple transmit waveforms with time and frequency synchronization constitutes a considerable challenge for multiple-input multiple-output (MIMO) synthetic aperture radar (SAR) systems. It is well-known that aliased signal returns may be separable by digital beamforming (DBF) on receive in elevation. However, the current orthogonal-waveform beamforming schemes significantly incr

Background: The diagnosis and treatment of childhood acute lymphoblastic leukemia (ALL) may impact mental health. We investigated the long-term risk of psychiatric disorders among survivors of ALL in a population-based cohort study. Methods: We identified patients diagnosed with ALL in Denmark and Sweden before age 20 during 1982–2008. Survivors of ALL (n = 2026), their siblings (n = 3027), and po

What if Women Ruled the World? Yael Bartana stages this question in her performative piece Two Minutes to Midnight. The all-female government of a fictional nation is tasked with addressing an imminent nuclear threat posed by a foreign power. A panel composed of actresses and real-life experts in defense, law, politics, and psychology gathers in a democratic “peace room.” This space reflects the t

BACKGROUND AND OBJECTIVE: The option to treat early colon cancer (CC) with local resection, as well as trials investigating neoadjuvant treatment, has increased the importance of identifying early-stage disease in the workup. Most CC patients are T- and N-staged preoperatively with CT, although its reliability in staging early CC remains elusive. The aim of this study was to investigate CT-staging

Background: As a widely distributed and aerial migratory bird, the Common Swift (Apus apus) flies over a wide geographic range in Eurasia and Africa during migration. Although some studies have revealed the migration routes and phenology of European populations, A. a. apus (from hereon the nominate apus), the route used by its East Asian counterpart A. a. pekinensis (from hereon pekinensis) remain

Polycystic ovary syndrome (PCOS) is a medical condition with important consequences for women’s well-being and reproductive outcomes. Although the etiology of PCOS is not fully understood, there is increasing evidence of both genetic and environmental determinants, including development in early life. We studied a population of 977,637 singleton women born in in Sweden between 1973 and 1995, follo

Finding a wear resistant coating for cemented carbide cutting tools in the machining of difficult to cut Ti alloys is a challenge due to their high strength and chemical reactivity. Tool manufacturers recommend physical vapor deposited (PVD) TixAl1-xN (x = 0.4–0.7), and an extra NbN overlayer has shown promising potential. This study explores wear mechanisms of PVD Ti0.45Al0.55N with and without N