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Kainate-induced seizures result in hippocampal neurodegeneration and spatial learning deficits in rodents. Previous studies show that rofecoxib, a selective cyclooxygenase-2 inhibitor, protects against kainate-induced hippocampal cell death 3 days after seizures. Our aim was to determine whether rofecoxib attenuates visuospatial learning deficits and late neuronal death after kainate-induced seizu

In beer, the main amphiphilic components are protein and iso-humulone. Two major populations of protein are identified as lipid transfer protein (LTP) (9.7 kDa) and protein Z (43 kDa). In this paper, protein and iso-humulone are extracted from barley malt and hop, respectively, based on the brewing process. Mixtures of protein and iso-humulone are mixed at different concentrations and centrifuged.

This paper presents a solution to the saturation problem in cascade control schemes. When cascade control approaches work in linear mode without saturation influence, important improvements can be achieved in industrial control loops. The effect of disturbances and/or nonlinear actuator behaviours on the main process variables can be considerably reduced. However, when saturation arises in the inn

BACKGROUND: Because hemodilution decreases the oxygen-carrying capacity of blood, it was hypothesized that severe hemodilution would decrease the tolerance to alveolar hypoxia. METHODS: Hemodynamics, oxygen transport, and blood lactate concentrations were compared in ten pigs with normal hematocrit (33 +/- 4%), and ten hemodiluted pigs (hematocrit 11 +/- 1%; mean +/- SD) anesthetized with ketamine

Inclusive production of D* mesons in deep-inelastic ep scattering at HERA is studied in the range 5 < Q(2) < 100 GeV2 of the photon virtuality and 0.02 < y < 0.7 of the inelasticity of the scattering process. The observed phase space for the D* meson is (pT) (D*) > 1.25 GeV and |eta( D*)| < 1.8. The data sample corresponds to an integrated luminosity of 348 pb(-1) collected with the H1 detector. S

Popular Abstract in Swedish Jag genomför i min avhandling en etisk analys av texter av tre samtida feministiska teologer: Chung Hyun Kyung, Sydkorea, Katie G. Cannon, USA och Mary C. Grey, Storbritannien. Genom valet av dessa tre teologer, verksamma i olika kulturella kontexter, iscensätter jag vad som kan kallas ett flerkulturellt samtal, där jag själv ingår som en part. I samtalet framträder bl In this thesis in ethics I study and analyze feminist theological texts from 1988–1997 by Katie G. Cannon, Chung Hyun Kyung and Mary C. Grey. A culturally diverse conversation is constructed, in which womanist issues, Asian women’s concerns, and feminist critique of the Western European philosophical and theological traditions are brought into dialogue with a Swedish context. The theories used are

Commercial potato protein concentrate (PPC) was investigated as a source of thermoformed bio-based plastic film. Pressing temperatures of 100 to 190 degrees C with 15 to 25% glycerol were used to form PPC films. The shape of the tensile stress-strain curve in thermoformed PPC was controlled by glycerol level and was independent of processing temperature. Tensile testing revealed that elongation at

This paper describes a method of finding thin, elongated structures in images and volumes. We use shortest paths to minimize very general functionals of higher-order curve properties, such as curvature and torsion. Our globally optimal method uses line graphs and its runtime is polynomial in the size of the discretization, often in the order of seconds on a single computer. To our knowledge, we ar

The standardization of work processes is a common feature of the public administration, aiming at both efficiency and equal treatment of citizens. Combining this standardization with employee motivation is considered a challenge. This challenge is explored, based on a survey to 261 social insurance officers (SIOs) at the Swedish Social Insurance Agency. Results reveal that, contrary to expectation

We present multi-epoch high-resolution optical spectroscopy, UV/radio/X-ray imaging, and archival Hubble and Spitzer observations of an intermediate luminosity optical transient recently discovered in the nearby galaxy NGC 300. We find that the transient (NGC 300 OT2008-1) has a peak absolute magnitude of M-bol approximate to -11.8 mag, intermediate between novae and supernovae, and similar to the

This study quantified major fluxes of carbon (C), heat and water, including uncertainty estimates, in a boreal forest in northern Sweden, using a process-based model (Coup-Model) and Bayesian calibration methodology. Coupled C, water and heat fluxes were described together with estimated uncertainties for all major components of the simulated C budget. Simulated mean gross primary production was 6

Objectives: To explore the views of experts about the development and validation of a robotic surgery training curriculum, and how this should be implemented. Materials and methods: An international expert panel was invited to a structured session for discussion. The study was of a mixed design, including qualitative and quantitative components based on focus group interviews during the European A

In this paper, standard-cell based memories (SCMs)are proposed as an alternative to full-custom sub-VT SRAM macros for ultra-low-power systems requiring small memory blocks. The energy per memory access as well as the maximum achievable throughput in the sub-VT domain of various SCM architectures are evaluated by means of a gate-level sub-VT characterization model, building on data extracted from

Background & Aims: RNA interference (RNAi) may offer new treatment options for chronic hepatitis B. Replicating via an RNA intermediate, hepatitis B virus (HBV) is known to be principally vulnerable to RNAi. However, beyond delivery, the relevant issues of potential off-target effects, target site conservation in circulating HBV strains, and efficacy of RNAi itself have not systematically been

High-throughput multiplexed protein quantification using mass spectrometry is steadily increasing in popularity, with the two major techniques being data-dependent acquisition (DDA) and targeted acquisition using selected reaction monitoring (SRM). However, both techniques involve extensive data processing, which can be performed by a multitude of different software solutions. Analysis of quantita

Background/Aims: Our purpose was to investigate whether the new research criteria for Alzheimer's disease proposed in 2007 by Dubois et al. are valid in a naturalistic memory clinic sample. Method: Retrospective diagnostic analyses were carried out to compare the traditional diagnostic criteria for dementia with the new criteria suggested by Dubois et al. No patient had gone through all procedures

Background High-dose aspirin (>= 500 mg daily) reduces long-term incidence of colorectal cancer, but adverse effects might limit its potential for long-term prevention. The long-term effectiveness of lower doses (75-300 mg daily) is unknown. We assessed the effects of aspirin on incidence and mortality due to colorectal cancer in relation to dose, duration of treatment, and site of tumour. Methods