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Survival benefits from concomitant chemoradiotherapy before radical surgery in stage IVA sinonasal mucosal melanoma?

BACKGROUND: The aim of the study was to review a local treatment protocol for sinonasal mucosal melanoma (SNMM) focusing on triple modality treatment (TMT), that is, neoadjuvant concomitant chemoradiotherapy (CRT) and surgery.METHODS: In a retrospective design, data on clinical presentation, treatment, and survival were retrieved for 22 consecutive patients from a tertiary referral center.RESULTS:

Effects of inhibitors of small- and intermediate-conductance calcium-activated potassium channels, inwardly-rectifying potassium channels and Na+/K+ ATPase on EDHF relaxations in the rat hepatic artery

1. In the rat hepatic artery, the SK(Ca) inhibitors UCL 1684 (300 nM) completely blocked, and scyllatoxin (1 μM) and d-tubocurarine (100 μM) partially inhibited EDHF relaxations when each of them was combined with charybdotoxin (300 nM). 2. The IK(Ca) inhibitors clotrimazole (3 μM) and 2-chlorophenyl-bisphenyl-methanol (3 μM) strongly depressed EDHF relaxations when each of them was combined with

X-Ray and molecular imaging during pregnancy and breastfeeding - When should we be worried?

Some of the ethically most sensitive issues in radiation protection arise at imaging of pregnant - and potentially pregnant - patients and of newborn. This article reviews the current literature and recommendations on imaging during pregnancy and breastfeeding. Risks related to alternative non-ionizing radiation methods are also considered. With few exceptions, exposure of the fetus through radiog

Open vs minimally invasive radical trachelectomy in early-stage cervical cancer : International Radical Trachelectomy Assessment Study

Background: Minimally invasive radical trachelectomy has emerged as an alternative to open radical hysterectomy for patients with early-stage cervical cancer desiring future fertility. Recent data suggest worse oncologic outcomes after minimally invasive radical hysterectomy than after open radical hysterectomy in stage I cervical cancer. Objective: We aimed to compare 4.5-year disease-free surviv

Ethnography of the socio-sanitary reception in Rome. How are HIV/AIDS and hepatitis b involved in creating the construction of legal categories assigned to migrants?

Purpose: This paper aims to investigate the role that Italian third sector organizations have in the process of social and administrative categorization of newly arrived migrants living with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/Aids) or hepatitis b. In Italy, free access to health is provided to all migrants and residence permits for medical treatment is granted for

A validation study of a consumer wearable sleep tracker compared to a portable EEG system in naturalistic conditions

Objective: To compare a wearable device, the Fitbit Versa (FV), to a validated portable single-channel EEG system across multiple nights in a naturalistic environment. Methods: Twenty participants (10 men and 10 women) aged 25–67 years were recruited for the present study. Study duration was 14 days during which participants were asked to wear the FV daily and nightly. The study intended to reprod

Effects of acetonitrile-water mixtures on α-chymotrypsin catalyzed dipeptide synthesis

α-Chymotrpysin (EC 3.4 21.1) was immobilized by deposition on celite and subsequent cross-linking with glutaraldehyde. The effects of different mixtures of aqueous buffer and acetonitrile on the immobilized preparation were evaluated using a dipeptide synthesis as model reaction. The initial reaction rate at 6-95% of water increased with increasing water content. The maximum yield of peptide had t

A Novel Microparticle Based Formulation for Topical Delivery of FOL-005, a Small Peptide

Although many therapeutically active peptides and proteins have been developed there is a lack of topical pharmaceutical products on the market containing these sensitive molecules. The main reasons may be lack of stability and a limitation of larger molecules to penetrate into the skin. In this study we investigated the possibility to develop a peptide formulation which enables follicular permeat

Creating and detecting poor man's Majorana bound states in interacting quantum dots

We propose and theoretically investigate an alternative way to create the poor man's Majorana bound states (MBSs) introduced in Phys. Rev. B 86, 134528 (2012)10.1103/PhysRevB.86.134528. Our proposal is based on two quantum dots (QDs) with strong electron-electron interactions that couple via a central QD with proximity-induced superconductivity. In the presence of spin-orbit coupling and a magneti

Biventricular Pressure-Volume Loop Assessment Before and After Pulmonary Valve Replacement in Tetralogy of Fallot

Patients with tetralogy of Fallot (TOF) may undergo pulmonary valve replacement (PVR) after initial full repair. We investigated indices of biventricular function, work and efficiency of TOF patients' using noninvasive pressure-volume (PV) loop analysis on cardiovascular magnetic resonance (CMR) images and compared pre-and post PVR groups. Biventricular segmentations of steady state free precessio

Ceremony 1998

Ceremony 1998 Sune Svanberg Atomfysik, LTH LLC/LUMLAC Lunds Universitet LUMLAC: www.mlc.lu.se BIOFOTONIK I LUND http://www5.lu.se/upload/GrafiskProfil/Logotyper/Lunds_universitet_C2r.zip Analytical Chemistry Review by Lund University Researchers (1989) Lund Laser Medicine Group 1983 - Medical Laser Centre 1991 - Appl. Spectr. 1984 Optics Lett. 1985 1990 LUMLAC Proposal Present biophotonics in Lund

https://www.mlc.lu.se/fileadmin/mlc/Minnesanteckningar/Biofotonik_Sune_Svanberg.pdf - 2026-05-28

Power, Justice and (De)coloniality in Development

Uppsala University - 7,5 credits This course addresses various aspects of power in development. Rather than adapting a post-colonial perspective in which development practices and politics is portrayed as something enacted by the global North on the global South, the course is situated in the debates around decolonization in the contemporary global context. About the courseThis course is situated

https://www.developmentresearchschool.lu.se/our-doctoral-courses/power-justice-and-decoloniality-development - 2026-05-27

Cécile Brokelind

Professor Contact details Email: cecile [dot] brokelind [at] har [dot] lu [dot] se Phone: +46 46 222 33 67Organisation Department of Business Law Room number: EC2-359 Service point: 10 WebpageCécile Brokelinds profile in Lund University research portalOther affiliations Researcher Lund Tax Academy Publications Displaying of publications. Sorted by year, then title. Filter by type AllBookBook chapt

https://www.lusem.lu.se/cecile-brokelind - 2026-05-27

Prevalence and risk factors for ischemia, leak, and stricture of esophageal anastomosis: Gastric pull-up versus colon interposition

BACKGROUND: Reports of esophageal anastomotic complications often involve more gastric than colonic reconstructions and are incomplete because of fragmented followup by physicians unfamiliar with the surgical procedure. STUDY DESIGN: Three hundred ninety-three consecutive esophagectomy patients had prevalence and risk factors determined for graft ischemia and anastomotic leak; 363 of these patient

Design of a horizontal neutron reflectometer for the European Spallation Source

A design study of a horizontal neutron reflectometer adapted to the general baseline of the long pulse European Spallation Source (ESS) is presented. The instrument layout comprises advanced solutions for the neutron guide, high-resolution pulse shaping and beam bending onto a sample surface being thoroughly adjusted to the properties of the ESS. The length of this instrument is roughly 55 m, enab

Advancing personalized care in hemophilia A: ten years' experience with an advanced category antihemophilic factor prepared using a plasma/albumin-free method.

Detailed analysis of data from studies of recombinant antihemophilic factor produced using a plasma/albumin-free method (rAHF-PFM) in previously treated patients showed a substantial level of interpatient variation in pharmacokinetics (PKs), factor VIII dosing, and annualized bleed rate (ABR), suggesting that individual patient characteristics contributed to outcome. For example, plasma half-life

A treatment planning and delivery comparison of volumetric modulated arc therapy with or without flattening filter for gliomas, brain metastases, prostate, head/neck and early stage lung cancer

Background. Flattening filter-free (FFF) beams are an emerging technology that has not yet been widely implemented as standard practice in radiotherapy centers. To facilitate the clinical implementation of FFF, we attempted to elucidate the difference in plan quality and treatment delivery time compared to flattening filter beams (i.e. standard, STD) for several patient groups. We hypothesize that

Bayes2016

Namnlös A Mini-conference on Bayesian Methods at Lund University 5th of February, 2016 Room B152, Lux building, Helgonavägen 3, Lund University. www.lucs.lu.se/bayes-at-lund-2016/ http://www.lucs.lu.se/bayes-at-lund-2016/ Program 12.15–12.45 Welcome and invited presentation . An Introduction to Bayesian computation and evidence synthesis us- ing STAN, Robert Grant, Faculty of Health, Social Care a

https://www.lu.se/sites/www.lu.se/files/bayes2016.pdf - 2026-05-28