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The potential of mean force between two spherical and like-charged macroions in a salt-free aqueous solution has been determined using an extended primitive model and canonical Monte Carlo simulations. The systems considered covered the range from a purely repulsive to a purely attractive potential of mean force as the electrostatic coupling was increased. The macroions were modeled as spherical d
Background: Early substitution of calcineurin inhibitor (CNI) with mammalian target of rapamycin inhibitors has been shown to improve kidney function and reduce intimal hyperplasia in heart transplant (HTx) recipients but data on long-term outcome of such a regime are still sparse. Methods: In the SCHEDULE trial, 115 de novo HTx recipients were randomized to (1) everolimus with reduced exposure of
Genome-wide association studies (GWAS) have begun to identify the common genetic component to ischaemic stroke (IS). However, IS has considerable phenotypic heterogeneity. Where clinical covariates explain a large fraction of disease risk, covariate informed designs can increase power to detect associations. As prevalence rates in IS are markedly affected by age, and younger onset cases may have h
Polymeric catalysts to be applied in the Diels-Alder cycloaddition of hexachlorocyclopentadiene and maleic acid have been prepared via molecular imprinting with template molecules immobilized on silica particles. These enzyme mimicking polymers exhibit specific catalytic effects compared to non-imprinted control polymers or polymer-free solutions. It could be demonstrated that the activity of the
Clinical characteristics and cytogenetic aberrations were ascertained and reviewed in a population-based consecutive series of 285 pediatric T-cell acute lymphoblastic leukemias (T-ALLs) diagnosed between 1992 and 2006 in the Nordic countries. Informative karyotypic results were obtained in 249 (87%) cases, of which 119 (48%) were cytogenetically abnormal. Most (62%) of the aberrant T-ALLs were ps
Black holes exceeding a billion solar masses have been detected at redshifts greater than six. The rapid formation of these objects may suggest a massive early seed or a period of growth faster than Eddington. Here we suggest a new mechanism along these lines. We propose that in the process of hierarchical structure assembly, dense star clusters can be contracted on dynamical timescales due to the
A variety of pathogenic bacteria can infect humans, and rapid species identification is crucial for the correct treatment. However, the identification process can often be time-consuming and depend on the cultivation of the bacterial pathogen(s). Here, we present a stand-alone, enzyme-free, optical DNA mapping assay capable of species identification by matching the intensity profiles of large DNA
Objectives: To evaluate the potential of artificial intelligence (AI) to identify normal mammograms in a screening population. Methods: In this retrospective study, 9581 double-read mammography screening exams including 68 screen-detected cancers and 187 false positives, a subcohort of the prospective population-based Malmö Breast Tomosynthesis Screening Trial, were analysed with a deep learning–b
By the incorporation of size-selected Au nano-particles in Ti Schottky contacts on silicon carbide, we could observe considerably lower the barrier height of the contacts. This result could be obtained for both n- and p-type Schottky contacts using current-voltage and capacitance voltage measurements. For n-type Schottky contacts, we observed reductions of 0.19-0.25 eV on 4H-SiC and 0.15-0.17 eV o
BACKGROUND: We measured serum levels of human glandular kallikrein 2 (hK2) in patients treated with radical retropubic prostatectomy (rrP) for clinically localized prostate cancer (PCa) with a total PSA (tPSA)-level below 10 ng/ml to investigate whether hK2 can be applied to preoperatively distinguish organ-confined (pT2a/b) from nonorgan-confined (> or = pT3a)-PCa more accurately than total PSA.
We propose a rational fabrication method for nanoimprinting moulds by scanning probe lithography. By wet chemical etching, different kinds of moulds are realized on Si( 110) and Si( 100) surfaces according to the Si crystalline orientation. The structures have line widths of about 200 nm with a high aspect ratio. By reactive ion etching, moulds with patterns free from the limitation of Si crystall
Workshop 18 oktober 2017: Ett hållbart Lunds universitet Dokumentation från Workshopen Framtidens hållbara universitet 18 oktober 2017 Workshopen var en del av vetenskapsveckan Framtidens universitet som arrangerades av Lunds universitet 16–22 oktober 2017. Workshopen arrangerades av Lunds universitets Hållbarhetsforum i samarbete med bland annat miljöavdelningen vid Lunds universitet, LUCSUS (Lun
https://www.hallbarhet.lu.se/sites/hallbarhet.lu.se/files/sammanfattning_workshopbord_18okt2017.pdf - 2026-05-28
Workshop 18 oktober 2017: Ett hållbart Lunds universitet Dokumentation från Workshopen Framtidens hållbara universitet 18 oktober 2017 Universitetet är en viktig drivkraft för en bättre värld genom både vår forskning och vår utbildning. Samtidigt belastar vi miljön genom vår verksamhet – lokaler, resor, allt det vi konsumerar och så vidare. Som en del av programmet under den sista vetenskapsveckan
https://www.hallbarhet.lu.se/sites/hallbarhet.lu.se/files/sammanfattning_workshopbord_18okt2017_1.pdf - 2026-05-28
Workshop 18 oktober 2017: Ett hållbart Lunds universitet Dokumentation från Workshopen Framtidens hållbara universitet 18 oktober 2017 Universitetet är en viktig drivkraft för en bättre värld genom både vår forskning och vår utbildning. Samtidigt belastar vi miljön genom vår verksamhet – lokaler, resor, allt det vi konsumerar och så vidare. Som en del av programmet under den sista vetenskapsveckan
https://www.hallbarhet.lu.se/sites/hallbarhet.lu.se/files/sammanfattning_workshopbord_18okt2017_0.pdf - 2026-05-28
Magnetic Resonance Imaging (MRI) has exhibited significant potential for quantifying cardiac function and dysfunction in the mouse. Recent advances in highresolution cardiac MR imaging techniques have contributed to the development of acquisition approaches that allow fast and accurate description of anatomic structures, and accurate surface and finite element (FE) mesh model constructions for stu
The copolymer of N-isopropylacrylamide (NIPAM) and methacryloyl derivative of spirobenzopyran (MSBP) with a molecular weight of 21 000 g/mol and the average molar MSBP content of 1.9% was prepared by free radical polymerization. The copolymer displayed its phase transition in water in the temperature range of 30-50 degreesC. UV irradiation of its aqueous solution caused photoinduced transformation
A diffusion process on complex networks is introduced in order to uncover their large-scale topological structures. This is achieved by focusing on the slowest decaying diffusive modes of the network. The proposed procedure is applied to real-world networks like a friendship network of known modular structure, and an Internet routing network. For the friendship network, its known structure is well
The pinch-off dynamics during hydrogen bubble formation was experimentally investigated in a cross-junction microchannel. A binarization interface recognizing and key frame tracking method was established. By analyzing the breakup dynamics through spatial and time domains, the effects of interfacial tension and viscosity on hydrogen bubble pinch-off were revealed. A transitional stage between a li
Objective: The optimal timing for transplantation is unclear in patients with Eisenmenger syndrome (ES). We investigated post-transplantation survival and transplantation-specific morbidity after heart-lung transplantation (HLTx) or lung transplantation (LTx) in a cohort of Nordic patients with ES to aid decision-making for scheduling transplantation. Methods: We performed a retrospective, descrip
