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This paper concerns the use of Sequential Monte Carlo methods (SMC) for smoothing in general state space models. A well known problem when applying the standard SMC technique in the smoothing mode is that the resampling mechanism introduces degeneracy of the approximation in the path-space. However, when performing maximum likelihood estimation via the EM algorithm, all involved functionals will b

OBJECTIVES:: To investigate the association between adverse events recorded during critical care and mortality in out-of-hospital cardiac arrest patients treated with therapeutic hypothermia. DESIGN:: Prospective, observational, registry-based study. SETTING:: Twenty-two hospitals in Europe and the United States. PATIENTS:: Between October 2004 and October 2008, 765 patients were included. INTERVE

Following a radiological or nuclear emergency event, there is a need for quick and reliable dose estimations of potentially exposed people. In situations where dosimeters are not readily available, the dose estimations must be carried out using alternative methods. In the present study, the optically stimulated luminescence (OSL) properties of tooth enamel and different dental repair materials hav

Background: Metabolic acidosis (MA) at birth is commonly defined as umbilical cord arterial pH <7.0 plus base deficit (BD) ≥12.0 mmol/L. BD is not a measured entity but calculated from pH and pCO(2) values, with the hemoglobin (Hb) concentration included in the calculation algorithm as a fixed or actual value. Various blood gas analyzers use different algorithms, indicating variations in the MA di

The concept of mindfulness refers to a state and a skill that is characterized by conscious awareness of the here-and-now, as well as an observing, accepting attitude to one’s own experiences. Various kinds of mindfulness-related methods have become increasingly more important during the last decade within cognitive and behavioural psychotherapy. The article contains a discussion of possible thera

I den här artikeln analyseras hur samhället beskrivs i svenska populärmedicinska texter om övervikt och fetma. Syftet är att placera de här beskrivningarna i ett historiskt och kulturellt sammanhang för att visa hur medicinska texter influeras av kulturella föreställningar och underliggande tankefigurer. Tydligt är att synen på samhället präglas av idén om en distinktion mellan ett förmodernt förr

To cite this article: Maurer M, Bader M, Bas M, Bossi F, Cicardi M, Cugno M, Howarth P, Kaplan A, Kojda G, Leeb-Lundberg F, Lötvall J, Magerl M. New topics in bradykinin research. Allergy 2011; DOI: 10.1111/j.1398-9995.2011.02686.x ABSTRACT: Bradykinin has been implicated to contribute to allergic inflammation and the pathogenesis of allergic conditions. It binds to endothelial B(1) and B(2) recep

Regular column on performing arts in the weekly newspaper Arbetaren (The Worker).

A number of microorganisms are capable of binding immunoglobulins (Igs) in a manner, which excludes binding to conventional antigen binding sites. Interaction of such bacterial proteins with surface immunoglobulins leads to polyclonal activation of B-lymphocytes. A recent example is Moraxella catarrhalis that binds to B lymphocytes in an IgD-dependent manner and induces proliferation and different

Abstract is not available

Dosage compensation, the process whereby expression of sex-linked genes remains similar between sexes (despite heterogamety) and balanced with autosomal expression, was long believed to be essential. However, recent research has shown that several lineages, including birds, butterflies, monotremes and sticklebacks, lack chromosome-wide dosage compensation mechanisms and do not completely balance t