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Background and purpose Sclerostin is produced by osteocytes and is an inhibitor of bone formation. Thus, inhibition of sclerostin by a monoclonal antibody increases bone formation and improves fracture repair. Sclerostin expression is upregulated in unloaded bone and is downregulated by loading. We wanted to determine whether an anti-sclerostin antibody would stimulate metaphyseal healing in unloa

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The next challenge for MIMO radio channel models is to simulate the time-variant nature of the channel correctly. Cluster-based MIMO channel models are well suited for this problem, however they currently lack an accurate parameterization of the time-variant cluster parameters. In this paper we identify and track clusters from three differentmeasurements conducted in an indoor, a sub-urban, and a

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High-speed communication using the copper network, originally installed for telephony, is one of the dominant Internet access techniques. Several variants of a technology referred to as digital subscriber line (xDSL) have been developed, standardized and installed during the last two decades. Essentially, xDSL achieves high rates by exploiting wide bands of the copper cable channel. The shorter th

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Increased logistics outsourcing and importance of supply chain integration (SCI) have attracted our interest in studying how logistics service providers (LSPs) are viewed as contributors to SCI and to their clients' performance. On the basis of LSPs? roles as they emerge from SCI-performance literature and from analysis of LSP-websites on how they communicate their role(s), we discuss how this dif

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Elsewhere I have argued that the notion of a normative agent-neutral reason is undermined by certain views on reasons; the existence of agent-neutral reasons can be questioned. Here I shall not repeat my doubts but rather address a way of expressing the distinction that I had not considered and which would, if correct, put an end to my worries about the soundness of this dichotomy. The idea, which