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In much of preindustrial Europe the manorial estate was an important institution in the rural economy. Despite a widespread view that the estates insured its tenants against uncertainties, there is little evidence that measures taken were efficient. This study uses the impact of grain prices on demographic outcomes as a measure of the efficiency of the manorial system in protecting its inhabitants
In this study we investigated whether single nucleotide polymorphisms (SNP) in the genes coding for BDNF (Val66Met) and VEGF (C2578A) may be associated with maladaptive strategies among suicide attempt patients. We found that BDNF Val66Met gene polymorphism probably affect avoidant coping strategies.
During GH therapy for 2.3-9.6 years a male adult onset (AO) GH deficient (GHD) patient with a diagnosis of a non-functioning adenoma, have no increased all-cause mortality. However, women with AO GHD are still at a slightly higher risk. This general improvement in mortality is due to; more contemporary regiment of cardiovascular drugs, a refinement of surgical procedures, besides GH therapy improv
Mobile communication systems are becoming increasingly heterogeneous as new standards emerge. Currently, the wireless operators are upgrading their existing 3G networks such as UMTS and CDMA2000 to different kinds of 4G networks such as LTE and WiMAX. We can witness these days that mobile terminals are having the capability to access many of these wireless network types. The networks are very diff
Dobutamine is a cardiotonic agent, developed as a racemate more than 30 years ago. The compound soon got the label "the beta 1-selective adrenoceptor agonist''. However, a closer examination of the enantiomers showed that (+)-dobutamine is predominantly a beta(1)- and beta(2)-adrenoceptor agonist with modest selectivity whereas (-)-dobutamine is predominantly an alpha(1)-adrenoceptor agonist. Neve
Five adult volunteers participated in a biokinetic study of radioactive polonium. Portions of about 10Bq of (209)Po were orally administrated to four of the volunteers in a single ingestion. The fifth volunteer ingested a daily amount of 53mBq of 209Po for 243d to study the time to achieve equilibrium between intake and excretion for protracted intakes. For the subjects ingesting single intakes of
Mixed-linkage β-glucans are fermented by the colon microbiota that give rise to SCFA. Propionic and butyric acids have been found to play an important role in colonic health, as well as they may have extraintestinal metabolic effects. The aim of the present study was to investigate how two whole-grain barley varieties differing in dietary fibre and β-glucan content affected caecal SCFA, gut microb
This study compared the caring situation, health, self-efficacy, and stress of young (16-25) informal carers (YICs) supporting a family member with mental illness with that of YICs supporting a friend. A sample of 225 carers, assigned to a family group (n = 97) or a friend group (n = 128) completed the questionnaire. It was found that the family group experiences a lower level of support and frien
In the present study, we compare modern and Quaternary ostracods from two lacustrine basins: Laguna Cari-Laufquen (41 degrees S) and Lago Cardiel (49 degrees S) in Patagonia. Taxonomic and quantitative analyses along with isotopic and chemical studies of the extant ostracod fauna indicate that distinct ostracod associations can be identified as a function of conductivity. Three ostracod associatio
Pancreatic stellate cells (PSCs) play a key role in the dense desmoplastic stroma associated with pancreatic ductal adenocarcinoma. Studies on human PSCs have been minimal due to difficulty in maintaining primary PSC in culture. We have generated the first conditionally immortalized human non-tumor (NPSC) and tumor-derived (TPSC) pancreatic stellate cells via transformation with the temperature-se
No consensus treatment regime exists beyond surgery for malignant peripheral nerve sheath tumours (MPNST), and the purpose of the present study was to find new approaches to stratify patients with good and poor prognosis and to better guide therapeutic intervention for this aggressive soft tissue cancer. From a total of 67 MPNSTs from Scandinavian patients with and without neurofibromatosis type 1
We aimed to validate a widely used US prediction model for vaginal birth after cesarean (Grobman et al. [8]) and modify it to suit Swedish conditions.
To investigate the role of P2Y1 and P2Y12 receptors in hypoxia- and adenosine diphosphate (ADP)-induced pulmonary vasoconstriction.
A measurement of the ZZ production cross section in proton-proton collisions at root s = 7 TeV using data corresponding to an integrated luminosity of 1.02 fb(-1) recorded by the ATLAS experiment at the LHC is presented. Twelve events containing two Z boson candidates decaying to electrons and/or muons are observed, with an expected background of 0.3 +/- 0.3(stat)(-0.3)(+0.4)(syst) events. The cro
The ATLAS experiment at the LHC has measured the production cross section of events with two isolated photons in the final state, in proton-proton collisions at root s = 7 TeV. The full data set collected in 2011, corresponding to an integrated luminosity of 4.9 fb(-1), is used. The amount of background, from hadronic jets and isolated electrons, is estimated with data-driven techniques and subtra
Objective: To identify effective interventions which improve quality of care for people with dementia (PwD) living at home. METHODS: MEDLINE-(via PubMed), CINAHL, PsycINFO and ISI Web of Science databases were searched. Inclusion criteria: (1) randomized controlled trials; (2) published in English-language, peer-reviewed journals between 1990 and 2012; (3) evaluated strategies to improve quality
The habenula is a phylogenetically conserved brain structure in the epithalamus. It is a major node in the information flow between fronto-limbic brain regions and monoaminergic brainstem nuclei, thus anatomically and functionally ideally positioned to regulate emotional, motivational and cognitive behaviors. Consequently, the habenula may be critically important in the pathophysiology of psychiat
Previous work on the metabolism of Lactobacillus reuteri ATCC 55730 anticipated a variability in the use of organic electron acceptors as a means to relieve metabolic redox problems. Therefore, investigations focusing on this unique metabolism of L. reuteri may reveal a basis for new probiotic properties. For instance, L. reuteri may use reactive aldehydes and ketones as electron acceptors to bala
We investigated NaCl diffusion between external bulk solution atid bihydrated rhontmorilIonite interlayers using atomistic molecular dynamics (MD) simulations. Two different bulk concentrations, 0.55 and 1.67 M, were tested. In both cases, the simulations showed that excess salt entered the niterlayers. Barriers for Cl- entering the interlayer were calculated from the potential of mean force using
