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Non-invasive evaluation of glymphatic function has emerged as a crucial goal in neuroimaging, and diffusion tensor imaging along the perivascular space (DTI-ALPS) has emerged as a candidate method for this purpose. Reduced ALPS index has been suggested to indicate impaired glymphatic function. However, the potential impact of crossing fibres on the ALPS index has not been assessed, which was the a
We present a new carbon isotope chemostratigraphy for the upper Cambrian carbonate succession of the south Anhui Province, South China, based on new δ13Ccarb data and conodont records. Paraconodont assemblages in the lower part and euconodonts in the middle to upper part of the section were obtained from samples from the Qingkeng Formation. The paraconodont occurrences enable us to recognize the r
BACKGROUND: Children often require pain management following surgery to avoid suffering. Effective pain management has consequences for healing time and quality of life. Ibuprofen, a frequently used non-steroidal anti-inflammatory drug (NSAID) administered to children, is used to treat pain and inflammation in the postoperative period.OBJECTIVES: 1) To assess the efficacy and safety of ibuprofen (
Abstract Intro A systematic review (SR) attempts to find, assess and summarize all the empirical evidence to answer a specific research question. We aim to explore to what extent reviews are included in doctoral theses from all universities with a medical faculty in Sweden, and to describe the type, topic and assess the methodological quality of the reviews. Methods Duplicate assessors independent
BackgroundBiological heterogeneity of large B cell lymphomas (LBCLs) is poorly captured by current prognostic tools, hampering optimal treatment decisions.MethodsWe dissected the levels of 1,463 serum proteins in a uniformly treated trial cohort of 109 patients with high-risk primary LBCL (ClinicalTrials.gov: NCT01325194) and correlated the profiles with molecular data from tumor tissue and circul
Objectives: Dyspnea, or breathlessness, is a frequent and distressing symptom among patients with heart and lung diseases, particularly in advanced cancer stages, where it affects up to 90% of lung cancer cases. This symptom considerably diminishes quality of life, leading to physical deconditioning, increased levels of anxiety and depression, repeated hospitalizations, and elevated mortality rate
Background/objectives: Mycosis fungoides (MF) is a rare malignancy, with an indolent course in the early stages of the disease. However, due to major molecular and clinical heterogeneity, patients at an advanced stage of the disease have variable responses to treatment and considerably reduced life expectancy. Today, there is a lack of specific markers for the progression from early to advanced st
Accurately representing and predicting hydrological processes in terrestrial ecosystems is crucial for understanding the impacts of global environmental change, particularly climate change. This doctoral thesis aims to advance the understanding of vegetation-hydrology interactions and provides new modelling approaches to enhance hydrological prediction abilities. The thesis is grounded in the eval
BACKGROUND: While the associations between pediatric non-obese metabolic dysfunction-associated fatty liver disease (MAFLD) and multiple diagnostic biomarkers are well-established, the role of a broader range of blood-based, urine-based, and body composition-based biomarkers for monitoring MAFLD are needed.METHODS: A pediatric cohort was established in Wuxi, China. We measured body composition bio
BackgroundIn the last three decades, the increasing trend in female employment in Bangladesh has been critically analyzed from a socioeconomic point of view; however, its impact on infant and young child feeding (IYCF) practices has yet to be systematically reviewed. The aim of this systematic review and meta-analysis is to investigate the association between these variables.MethodsA systematic li
This article investigates changes in the right to social assistance – a means-tested cash support programme, regulated by the Social Services Act – for irregularised migrants over a period of four decades, 1982–2022. The article makes the case that austerity policies have hollowed out the right to support, with significant repercussions for those with irregularised residency status. In doing so, i
This study investigates building of trust between service providers and consumers on peer-to-peer tourist accommodation platforms by focusing on their affordances. Trust is necessary for peer-to-peer exchanges to happen. Platforms, as technological intermediaries afford specific actions that can result in trust, for example mutual consumer-provider reviews. Use of the same measures may imply suspi
