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Background: Prostate-specific membrane antigen positron emission tomography/computed tomography (PSMA PET/CT) enables sensitive detection and staging of prostate cancer, yet its relationship with long-term survival remains unclear. This study aimed to assess whether total lesion volume (TLV) measured on [18F]PSMA-1007 PET/CT predicts overall survival (OS) in prostate cancer patients. Methods: A co
Amelogenin self-assembly is a critical step in enamel matrix organization, supporting the spatial confinement of transient ACP and orchestrating hydroxyapatite nucleation and ordered growth. Studies have demonstrated that amelogenin self-assembles into nanoribbons by forming an amyloid-like structure that matches the cross-β pattern observed in the developing enamel matrix. However, molecular dete
Air pollution is the world’s deadliest environmental risk factor. Yetthere is little effort to educate the public about personal exposureto pollutants such as particulate matter (PM). This paper presentsthe design and implementation of a portable sensor box (PSB) tocollect local, spatially highly resolved particulate matter data. Tocounteract common inaccuracies in mobile particulate matter mea-su
The European Commission defines the Green Transition as the transformation set out in the European Green Deal. Ensuring that this transition is just is both an ethical requirement and a practical condition for maintaining public support and policy effectiveness. This Perspective proposes a multidimensional framework for assessing justice in Green Transition policies, encompassing distributional, p
The evacuation of hospitals in the event of fires and similar emergencies can be a difficult endeavor. Patients usually require assistance, with a considerable number of them being unable to evacuate by themselves due to medical conditions or due to the treatment they are receiving. Assistance is to be provided by the healthcare staff in the affected ward, which means that their level of preparedn
Vad kännetecknar egentligen kapitalismen, hur fungerar den och varför är den så seglivad? Harvardhistorikern Sven Beckert reder ut begreppen på mer än 1 300 sidor.
The mountain front recharge (MFR) process significantly influences the movement of water and dissolved organic carbon (DOC) in alpine catchments. However, no existing watershed models can adequately simulate this process, hindering accurate quantification of streamflow and DOC dynamics. To address this gap, this study explicitly incorporated the MFR process into a watershed-scale integrated water–
The climate change in northern Europe is not only leading to more extreme weather events but also causing long dry summers. This affects the moisture content of the ground and the vegetation. Causing an increased number of wildfires within Germany posing a risk to the environment, society, and firefighters. Surface fire spread in wildfires can be influenced by several environmental conditions and
Ni1+δSn (δ = 0.2, 0.4) and Ni1+δ(In/Sb) (δ = 0.1–0.5) (NiAs/Ni2In type) were synthesized, and their crystal structures were studied in this report. In Ni1+δ(In/Sb), the excess nickel atoms (δ = 0.1–0.5) occupy the vacant trigonal bipyramidal interstitial sites in the NiAs-type structural arrangement, leading to the evolution of a fully disordered to ordered superstructure through a series of incom
Aims Social anxiety disorder (SAD) is one of the most common anxiety disorders and is associated with significant impairment and societal costs. The association between SAD and mortality remains poorly understood, partly because in epidemiological research it is rarely studied independently from other anxiety disorders. In this population-based matched cohort and sibling control study, we estimate
Background: Increasing healthcare demands and a growing nursing shortage contribute to high workloads, psychosocial strain, and risks to care quality. Organisational conditions, job demands, and resources strongly influence nurses’ well-being, retention, and performance. Aim: To examine how nurses balance organisational demands and opportunities, and how these factors relate to work environment, w
Almost no seminar, book, or YouTube tutorial on successful public speaking is without the established and traditional “cork exercise.” It is supposed to enhance speakers’ rhythm and intelligibility, for which there is, however, no scientific evidence so far. Our experiment addresses this gap. Twenty speakers performed a presentation task three times: (1) before a cork exercise intervention, (2) im
A string of speech is a string of syllables, a series of varying amounts of jaw openings/closings. Neutralizing the vowel-intrinsic jaw opening indicates a pattern of jaw opening matching the utterance syllable prominence patterns. The hypothesis is that the jaw-opening patterns ensue from the metrical hierarchy of the language, such that for languages such as English, we see exponentially increas
Purpose: The purpose of this in-depth interview study was to explore how parents of children with sensorineural hearing loss (SNHL) experienced genetic testing and whether they experienced risks and benefits. Background: Most children with SNHL have a genetic etiology, which can be identified through genetic sequencing. A genetic test does not influence treatment, and whether patients and parents
This paper investigates a behavioral-feedback SIR model in which the infection rate adapts dynamically based on the fractions of susceptible and infected individuals. We introduce an invariant of motion and we characterize the peak of infection. We further examine the system under a threshold constraint on the infection level. Based on this analysis, we formulate an optimal control problem to keep
Abstract – Background: Cytologic examination of lymph nodes and serous effusions is of value in the diagnosis of small cell lymphomas. The World Health Organisation (WHO) has recently published a reporting system relating to the cytologic examination of lymph nodes, spleen, and thymus to standardise the approach to reporting such specimens. Summary: An overview of the WHO reporting system is given
Enhancing the transformation-induced plasticity effect in steel-based binders through deformation-induced martensitic transformation requires careful control of the austenite stability. This study investigated the effect of binder fraction on the thermal stability of austenite in the WC-(Fe,Ni) system with different binder contents within the WC + binder + graphite equilibrium region. Binder marte
Effective control over the alignment of 2D nanomaterials in solution is critical for optimizing their macroscopic properties. However, the fundamental factors governing this alignment remain poorly understood. This study addresses this gap by investigating the disorder-to-order transition states of Ti3C2Tx MXene sheets. We specifically examine the interplay among sheet sizes, concentrations, and s
