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New collaborative project tackles previously unknown mechanisms of Parkinson´s dyskinesias

The project addresses new hypotheses using mouse models of PD treated with drugs mimicking dopamine. People with Parkinson´s disease (PD) often develop abnormal involuntary movements (dyskinesias) during the course of their treatment with dopaminomimetic drugs.  In this new collaborative project, Angela Cenci Nilsson (Lund), Mattias Rickhag (Copenhagen) and Gilad Silberberg (Stockholm) will unrave

https://www.multipark.lu.se/article/new-collaborative-project-tackles-previously-unknown-mechanisms-parkinsons-dyskinesias - 2025-08-27

Genetic tools for studying Parkinson’s Disease – PhD interview with Martino Avallone

Martino Avallone defends his thesis on the 29th of September 2023. Martino Avallone spent the past four years developing tools for mapping gene expression and proteins in the brain to investigate basic biological questions and to elucidate the molecular mysteries contributing to Parkinson’s disease. On 29 September, he defends his thesis work done in the Molecular Neuromodulation research group. H

https://www.multipark.lu.se/article/genetic-tools-studying-parkinsons-disease-phd-interview-martino-avallone - 2025-08-27

Neuroimmune crosstalk in early Alzheimer’s disease – PhD interview with Megg Garcia-Ryde

Megg Garcia-Ryde defends her thesis on the 10th of October 2023. Megg Garcia-Ryde’s thesis sheds light on the early pathological processes in Alzheimer’s disease and the interplay between neurons and microglia as the disease evolves. October 10, she defends her thesis. Now, she gives her perspectives from a close collaboration between two of MultiPark’s experimental research groups and how she bri

https://www.multipark.lu.se/article/neuroimmune-crosstalk-early-alzheimers-disease-phd-interview-megg-garcia-ryde - 2025-08-27

Making the invisible visible: the magic of microscopic images

At the Multipark Café, Tomas Björklund explained the complexity of the brain to an interested audience. Photo: Bodil Malmström In today's scientific world, microscopic images have become a powerful resource for research. With access to advanced microscopes, researchers can now create unique images of structures and objects. Beautiful and captivating images that can also convey complex context to a

https://www.multipark.lu.se/article/making-invisible-visible-magic-microscopic-images - 2025-08-27

New blood marker can identify Parkinsonian diseases

Photo: iStock/Gab13 Is it possible that a single biomarker can detect all types of diseases related to dopamine deficiency in the brain? Yes, that's what a research group in Lund is discovering. "We have observed that an enzyme in cerebrospinal fluid and in blood is a useful marker for identifying all types of Parkinson's-related diseases with high accuracy," says Oskar Hansson, who led the study.

https://www.multipark.lu.se/article/new-blood-marker-can-identify-parkinsonian-diseases - 2025-08-27

Gene expression in Parkinson’s disease – PhD interview with Jana Rájová

Jana Rájová defends her thesis on the 23th of October 2023. Jana Rájová’s research turns light on gene expression in different parts of the brain affected by Parkinson’s disease. October 23, she defends her thesis in the Molecular Neuromodulation research group. In this interview, she tells about how it has been to combine wet and dry lab work and about the technical advances in the field. Tell us

https://www.multipark.lu.se/article/gene-expression-parkinsons-disease-phd-interview-jana-rajova - 2025-08-27

A closer look at the making of a novel stem cell therapy for Parkinson’s Disease

Many steps needs to be taken to bring a novel stem cell therapy for Parkinson’s Disease, STEM-PD, from the lab to the clinic. Illustration by Katrine Bech Lauritzen. A recent publication by MultiPark researchers at Lund University’s Lund Stem Cell Center gives a closer look at the making of a novel stem cell therapy for Parkinson’s Disease, STEM-PD, which has been approved for a Phase I/IIa clinic

https://www.multipark.lu.se/article/closer-look-making-novel-stem-cell-therapy-parkinsons-disease - 2025-08-27

MAXIV for high resolution, sub-cellular x-ray measurements – A special interest group

MAXIV offers new techniques to unravel structural changes in biomolecules of interest to researchers in neurodegeneration. Sweden has made significant strategic investments into the national infrastructure MAX IV, with world-unique instruments usable across disciplines. One emerging area is within medical sciences. MultiPark researchers now gather across research groups to facilitate the usage of

https://www.multipark.lu.se/article/maxiv-high-resolution-sub-cellular-x-ray-measurements-special-interest-group - 2025-08-27

How Mobile DNA Shapes the Human Brain

Researchers at Lund University have discovered that a specific group of genetic elements in our DNA influence the development of the human brain, their study was published in Science Advances. Photo: Phonlami Photos at Canva.com The human brain is an incredibly intricate organ that regulates everything from our motor skills to our memories. But how did it evolve into the complex structure we see t

https://www.multipark.lu.se/article/how-mobile-dna-shapes-human-brain - 2025-08-27

Generating GABAergic interneurons – PhD Interview with Andreas Bruzelius

Andreas Bruzelius defended his Ph.D. thesis "Generating GABAergic interneurons through reprogramming and differentiation strategies" on Friday, 20 October 2023. Andreas Bruzelius, a Ph.D. student at Lund University, defended his PhD thesis on Friday, 20 October 2023. Andreas' research focuses on generating brain cells, specifically interneurons, in the lab, which has significant implications for t

https://www.multipark.lu.se/article/generating-gabaergic-interneurons-phd-interview-andreas-bruzelius - 2025-08-27

New imaging approach visualizes early structural changes of amyloids in living brain tissue

With the O-PTIR technique, researchers can follow the aggregation of Alzheimer's proteins in fresh samples of the brain tissue. Illustration: William Bellomy Understanding the very first pathological events at the molecular level is key to developing treatments preventing neurodegenerative diseases. With a novel microspectroscopy approach combining optical and photothermal imaging, MultiPark resea

https://www.multipark.lu.se/article/new-imaging-approach-visualizes-early-structural-changes-amyloids-living-brain-tissue-0 - 2025-08-27

Extended cooperation between MultiPark and the patient organization Parkinson Skåne

The collaboration between MultiPark and Parkinson Skåne has been ongoing for many years and includes different interactive activities. In August 2023, MultiPark arranged a vernissage with brain pictures captured through the microscope. Every year, the patient organization Parkinson Skåne organizes a half-day of themed lectures on Parkinson's disease. The strategic research area, MultiPark, usually

https://www.multipark.lu.se/article/extended-cooperation-between-multipark-and-patient-organization-parkinson-skane - 2025-08-27

Double up! MultiPark gets two new Vice Coordinators

MultiPark's new vice coordinators Maria H Nilsson and Per Odin next to the coordinator Angela Cenci Nilsson at the MultiPark retreat in November 2023. January 2024 is the start of a new electoral term for MultiPark’s management. While Angela Cenci Nilsson will remain the coordinator, Oskar Hansson will be replaced for the next three years. The vice coordinator's mission will be shared between a he

https://www.multipark.lu.se/article/double-multipark-gets-two-new-vice-coordinators - 2025-08-27

Researchers have found the genetic cause for a type of hereditary ataxia, SCA4 – for long an unresolved conundrum

Spinocerebellar ataxias, SCA diseases, are a large group of rare, hereditary diseases in which difficulties in coordinating movements are common. Researchers have now solved the mystery behind one of SCA's diseases. Image: iStock/Andriy Yalanskyi. Intensive efforts are being made in medical research to discover the genomic causes of undiagnosed hereditary diseases. Persistent work and new technolo

https://www.multipark.lu.se/article/researchers-have-found-genetic-cause-type-hereditary-ataxia-sca4-long-unresolved-conundrum - 2025-08-27

Lund University launches an international recruitment programme for young researchers

Join our dynamic research community and advance your academic career. Photo: Johan Persson. To stimulate the international recruitment of excellent young researchers, Lund University has launched a call for positions as associate senior lecturers (biträdande universitetslektor) reserved for candidates with postdoctoral research experience in institutes outside of Sweden (and not having held a posi

https://www.multipark.lu.se/article/lund-university-launches-international-recruitment-programme-young-researchers - 2025-08-27

New study: Lost brain function restored after stroke

Image: iStock. Researchers have succeeded in restoring lost brain function in mouse models of stroke using small molecules that in the future could potentially be developed into a stroke therapy. “Communication between nerve cells in large parts of the brain changes after a stroke and we show that it can be partially restored with the treatment", says Tadeusz Wieloch, senior professor at Lund Univ

https://www.multipark.lu.se/article/new-study-lost-brain-function-restored-after-stroke - 2025-08-27

Turning academic discoveries into therapies – How the MultiPark Innovation Office helps

The team behind the innovation consists of Tadeusz Wieloch, Carin Sjölund, Roger Olsson, Karsten Ruscher, and Kerstin Beirup. Photo: Ingemar Hultquist. MultiPark researchers have discovered a new promising pharmacological approach stimulating recovery after stroke. Professor Tadeusz Wieloch tells about how the MultiPark Innovation Office supported the first steps in converting their academic resea

https://www.multipark.lu.se/article/turning-academic-discoveries-therapies-how-multipark-innovation-office-helps - 2025-08-27

Transposable elements in the healthy and diseased human brain: A Ph.D. Interview with Raquel Garza Gómez

Raquel Garza Gómez defends her Ph.D. thesis “Transposable elements in the healthy and diseased human brain " on Friday, January 19th. Raquel Garza Gómez is a Ph.D. student at Lund University, who will be defending her thesis on January 19, 2024. With a background in computational biology, Raquel's research focuses on studying the role of transposable elements in the human brain. Transposable eleme

https://www.multipark.lu.se/article/transposable-elements-healthy-and-diseased-human-brain-phd-interview-raquel-garza-gomez - 2025-08-27

United Neuroscience Campus Lund – Rostock (UNC)

The United Neuroscience Campus (UNC) is a partnership between MultiPark and the Centre for Transdisciplinary Neurosciences Rostock (CTNR) at the University Medical Centre Rostock, which started by a signed agreement (“Memorandum of understanding”) in May 2022. The UNC is a virtual campus beyond the Lund and Rostock locations on key neuroscience topics. It aims to increase the cooperation and mobil

https://www.multipark.lu.se/article/united-neuroscience-campus-lund-rostock-unc - 2025-08-27

World Parkinson's Day in Lund

MultiPark is proud to co-fund and support World Parkinson's Day in Lund - 11 April 2024. World Parkinson's Day (WPD) is a global healthcare event celebrated on the 11th of April every year. It brings together all of us who care about Parkinson´s disease, in different capacities, around the world. To celebrate WPD, MultiPark and Parkinson Skåne have co-organised a symposium where frontline overview

https://www.multipark.lu.se/article/world-parkinsons-day-lund - 2025-08-27