Insulin which is released by pancreatic beta-cells is the main regulator of blood sugar. Previous and current studies by a research group at Lund University in Sweden have identified around hundred different receptors on the surface of the beta-cells, with a diverse functional impact on the beta-cells. Now researchers at Lund University in collaboration with researchers at University of Sharjah, U

https://www.ludc.lu.se/article/key-mechanism-insulin-release-cholesterol-metabolite-found - 2025-08-25

An international research collaboration led by researchers from the Universities of Helsinki and Oxford has identified the biological mechanism through which a genetic variant protects against type 2 diabetes. The study, published in the journal Nature Genetics, finds that changes in a gene which makes zinc transporter proteins reduce the risk of type 2 diabetes by enhancing insulin secretion from

https://www.ludc.lu.se/article/study-decodes-gene-function-protects-against-type-2-diabetes - 2025-08-25

There are delicious smells emanating from the kitchen at the Malmö apartment of nutrition physiologist, Louise Brunkwall. Today, she is making pasta and vegetable sauce for lunch. A clean up before the interview with LUM means she can no longer find anything in the kitchen cupboards: “Usually there is always some kind of organised chaos here!” Louise Brunkwall likes to add red lentils to make cass

https://www.ludc.lu.se/article/help-your-body-outwit-reptile-brain - 2025-08-25

New research shows that it is possible to predict the development of type 1 diabetes. By measuring the presence of autoantibodies in the blood, it is possible to detect whether the immune system has begun to break down the bodys own insulin cells. "In the TEDDY study we have found that autoantibodies often appear during the first few years of life", said professor Åke Lernmark from Lund University

https://www.ludc.lu.se/article/early-signs-young-children-predict-type-1-diabetes - 2025-08-25

New results from the Environmental Determinants of Diabetes in the Young (TEDDY) study showed an association between prolonged enterovirus infection and the development of autoimmunity to the insulin-producing pancreatic beta-cells that precedes type 1 diabetes (T1D). Notably, researchers also found that early adenovirus C infection seemed to confer protection from autoimmunity. The full findings

https://www.ludc.lu.se/article/unexpected-viral-behavior-linked-type-1-diabetes-high-risk-children - 2025-08-25

Sweden and Denmark are among the countries in the world with the highest type-1 diabetes prevalence. Both countries have a long tradition of excellent research and treatment, and with the new joint diabetes project DiaUnion, supported by the EU's Interreg program, we are bridging research among the two countries to jointly put in an extra effort to fight the deadly disease. The DiaUnion project st

https://www.ludc.lu.se/article/denmark-and-sweden-join-forces-against-diabetes - 2025-08-25

Using lipidomics, a technique that measures the composition of blood lipids at a molecular level, and machine learning, researchers at Lund University in Sweden have identified a blood lipid profile that improves the possibility to assess, several years in advance, the risk of developing type 2 diabetes. The blood lipid profile can also be linked to a certain diet and degree of physical activity.

https://www.ludc.lu.se/article/blood-lipid-profile-predicts-risk-type-2-diabetes-better-obesity - 2025-08-25

Niels Grarup, Novo Nordisk Foundation Centre for Basic Metabolic Research at the University of Copenhagen, will recieve the Leif C. Groop Award for Outstanding Diabetes Research. In his research, he has shown, among other things, that there is a genetic explanation for the increase in type 2 diabetes in Greenland. The prize, worth SEK 100 000, is sponsored by the pharmaceutical company Novo Nordis

https://www.ludc.lu.se/article/award-research-gene-increases-risk-type-2-diabetes-greenland - 2025-08-25

One of Europe’s largest type 1 diabetes research cooperations has passed a significant milestone: The international platform GPPAD (“The Global Platform for the Prevention of Autoimmune Diabetes”) has successfully included 520 babies across Europe in the type 1 diabetes prevention trial POInT (Primary Oral Insulin Trial) – half of the targeted 1040 participants. The POInT study aims to train the i

https://www.ludc.lu.se/article/halfway-there-biggest-type-1-diabetes-prevention-trial-babies-reaches-important-milestone - 2025-08-25

Stina Ramne is the recipient of the DPLU PhD Student Prize 2019. In her research in nutritional epidemiology she focuses on intake of added sugar and risk of diabetes and cardiometabolic disease. In the video Stina Ramne describes her reserach and the project she got the DPLU Student Prize for.

https://www.ludc.lu.se/article/video-dplu-phd-student-prize-2019-stina-ramne - 2025-08-25

The more sugar we eat, the lower intake of vitamins and minerals we have, show new findings from Lund University Diabetes Centre. Esther González-Padilla Photo: Sara Liedholm High sugar intake has been associated with numerous diseases and conditions such as dental caries, obesity, diabetes, and cardiovascular disease. In this study the researcher have examined the effect of added sugar - that is

https://www.ludc.lu.se/article/more-sugar-less-vitamins-study-shows - 2025-08-25

JDRF honors type 1 diabetes research leaders, among them prof Åke Lernmark, Lund University Diabetes Centre. JDRF, the leading global organization funding type 1 diabetes (T1D) research, has announced the winners of five prestigious research awards: the George Eisenbarth Award for T1D Prevention; the Gerold and Kayla Grodsky Basic Research Scientist Award; the Mary Tyler Moore and S. Robert Levine

https://www.ludc.lu.se/article/jdrf-award-ake-lernmark - 2025-08-25

Diabetes, cardiovascular disease, Parkinson's and Alzheimer's disease make up the world’s most common diseases. A new biobank at Lund University in Sweden - the largest of its kind - with stem cells from both those affected and healthy individuals, will contribute to an increased understanding of how these diseases arise. Human IPS cells. Photo: Johan Jakobsson “The goal is for researchers to be a

https://www.ludc.lu.se/article/worlds-largest-stem-cell-biobank-launched - 2025-08-25

Lund University Diabetes Centre (LUDC) was ranked as one of Sweden's three best research environments in the medical sciences in the Final Evaluation of the Linnaeus funding program. - It was really gratifying to read the report. We are very proud to see how the long-term efforts have paid off and positioned LUDC among the highest-ranked Centers of Excellence in Sweden, both with regards to resear

https://www.ludc.lu.se/article/ludc-top-ranked-national-evaluation - 2025-08-25

Message from the LUDC Executive Board. Photo by CDC on Unsplash Dear Friends and colleagues,We are all now well aware that the COVID-19 pandemic is spreading fast in Sweden and around the world. There is a lot of information to digest. Some of this is factual and helpful, but there is also a great deal of poorly informed speculation, that risks promoting anxiety and panic. As biomedical scientists

https://www.ludc.lu.se/article/updates-covid-19 - 2025-08-25

A method that will quickly and easily detect diabetic neuropathy, nerve damage caused by high blood sugar, is under development. The aim is to identify individuals in the risk zone so that it is possible to initiate early treatment to prevent, or even reverse, the development. Neuropathy can be difficult to diagnose. It covers many different nerve types, can express itself in several different way

https://www.ludc.lu.se/article/screening-reveals-early-nerve-damage - 2025-08-25

Article in The Conversation by Paul Franks, professor of genetic epidemiology and Peter M Nilsson, professor of internal medicine - epidemiology at Lund University. Photo by CDC on Unsplash A growing number of Swedish doctors and scientists are raising alarm over the Swedish government’s approach to COVID-19. Unlike its Nordic neighbours, Sweden has adopted a relatively relaxed strategy, seemingly

https://www.ludc.lu.se/article/sweden-under-fire-relaxed-coronavirus-approach-heres-science-behind-it - 2025-08-25

In type 2 diabetes, the body’s cells are unable to assimilate the essential hormone insulin which is produced in the beta cells of the pancreas. Exactly what is wrong with the beta cells in type 2 diabetes is the question to which Professor Erik Renström at Lund University Diabetes Centre is searching for an answer. After just over twenty years of successful research in the field, he is now being

https://www.ludc.lu.se/article/nordic-award-research-what-wrong-beta-cells-type-2-diabetes - 2025-08-25

Olle Melander, professor of Internal Medicine and consultant at Skåne University Hospital, has received the prestigious European Research Council’s (ERC) Advanced Grant of approximately SEK 25 million. Olle Melander. Photo: Mikael Risedal Olle Melander, Professor of Internal Medicine, does research on new preventive treatments for diabetes and cardiovascular disease.“It feels incredibly inspiring

https://www.ludc.lu.se/article/olle-melander-awarded-erc-advanced-grants - 2025-08-25

Oktawia Nilsson's doctoral thesis describes Apolipoprotein A-I (shortly named ApoA-I), the main protein of HDL also known as “the good” cholesterol. Based on the experiments performed in the scientific papers included in this thesis, we propose that ApoA-I can be used as a promising treatment for diabetes and cardiovascular diseases. However, some people with genetic predispositions are born with

https://www.ludc.lu.se/article/apolipoprotein-i-good-player-dark-side - 2025-08-25