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Best treatment for cardiac arrest – new international study will provide answers

Picture: iStock/Chalabala. The guidelines governing the treatment of sudden cardiac arrest exhibit variation across different nations, with treatment strategies often resting on a limited evidential foundation. A randomized international study is underway poised to address some of the most pivotal questions. Encompassing a cohort of 3,500 patients, this study aims to scrutinize the impact of diffe

https://www.medicine.lu.se/article/best-treatment-cardiac-arrest-new-international-study-will-provide-answer - 2025-08-27

New treatment of atherosclerosis may reduce the risk of a heart attack

Vikas Yadav, Jan Nilsson, and Filiz Serifler at Lund University Diabetes Centre have contributed to the studies of the antibody that neutralises oxidised LDL particles. Photograph: Petra Olsson A treatment that has reduced plaque development in animals has now been tested in people with psoriasis. Jan Nilsson at Lund University is one of the researchers behind the clinical study that showed a redu

https://www.medicine.lu.se/article/new-treatment-atherosclerosis-may-reduce-risk-heart-attack - 2025-08-27

Update STEM-PD clinical trial – stem cell-based transplant for Parkinson’s disease

Photo from stem cell transplantation at Skåne University Hospital. Source: Skåne University Hospital. Higher dose cohort initiated after positive early safety evaluation in Parkinson's therapy. After a positive initial safety evaluation, the pioneering STEM-PD clinical trial has advanced to higher dose testing. STEM-PD is a first-in-human clinical trial testing a new investigational therapy for Pa

https://www.medicine.lu.se/article/update-on-stem-pd-clinical-trial-stem-cell-based-transplant-parkinsons-disease - 2025-08-27

Cell-specific Biomarkers in the Blood Reflect What Happens in the Brain During Stroke

Three of the Lund University researchers that studied the brain environment of patients during an ongoing stroke. From left: Andreas Enström, Gesine Paul-Visse and Arne G. Lindgren. Photo: Ingemar Hultquist. By analysing small microvesicles that cells release to communicate with their surroundings in the blood, researchers at Lund University map what happens in the brains of stroke patients. The s

https://www.medicine.lu.se/article/cell-specific-biomarkers-blood-reflect-what-happens-brain-during-stroke - 2025-08-27

The war between bacteria and their virus

Bacteriophage attacking a bacteria. Photo: iStock There is a constant war between bacteria and their viruses, bacteriophages, where both try to outsmart each other. An international study led by Lund University provided an important missing bit to the puzzle of how the bacteria defend themselves against phages. This is an important stepping stone towards developing effective phage-based therapies

https://www.medicine.lu.se/article/war-between-bacteria-and-their-virus - 2025-08-27

Research paves the way for sustainable dietary guidelines

Foto: iStock/Magda Tymczyj. The EAT-Lancet diet is a framework designed to promote environmental sustainability while also preventing common diseases such as type 2 diabetes. How do we know if the diet actually works? An international research team studied seven dietary scores and found that two of them were particularly good at evaluating adherence to the diet. Reliable diet scores are important

https://www.medicine.lu.se/article/research-paves-way-sustainable-dietary-guidelines - 2025-08-27

New method allows for large-scale screening for autoimmune diseases

A new method can be used for large-scale screening for type 1 diabetes. The blood test can be done at home. Photograph: Petra Olsson. Interest in type 1 diabetes screening is growing as methods improve and new treatments become available to more patients. New research at Lund University demonstrates how screening for autoimmune diseases can be carried out on a large-scale basis. A new treatment th

https://www.medicine.lu.se/article/new-method-allows-large-scale-screening-autoimmune-diseases - 2025-08-27

The recipe for a great antibody

"The hybrid antibody is significantly better than the body's own antibodies at fighting both streptococcus and SARS-CoV-2", say the researchers behind the discovery Arman Izadi and Pontus Nordenfelt. Photo: Tove Smeds.. Antibodies are the body's superheroes, recognizing and eliminating disease-causing substances. By combining parts from antibodies, researchers at Lund University have designed a hy

https://www.medicine.lu.se/article/recipe-great-antibody - 2025-08-27

New peptide may reduce the risk of diabetes complications

Jan Nilsson's research group has identified a substance that stimulates the repair capacity and growth of vascular cells. Biomedical analyst Filiz Serifler has contributed to the project. Photo: Petra Olsson Heart attack and stroke are common complications of diabetes, as the body's ability to repair and form vessels is impaired. Researchers at Lund University have developed a new substance with t

https://www.medicine.lu.se/article/new-peptide-may-reduce-risk-diabetes-complications - 2025-08-27

Professor Filipe Pereira awarded ERC Proof of Concept Grant

By reprogramming tumour cells to become the body’s defenders, Filipe Pereira and his colleagues hope to improve current cancer treatments.. Foto: Johan Persson Filipe Pereira and his research team have discovered a recipe on how to reprogram cancer cells into antigen-presenting dendritic cells, essential for initiating and enhancing anti-tumour immunity. This approach provides a promising strategy

https://www.medicine.lu.se/article/professor-filipe-pereira-awarded-erc-proof-concept-grant - 2025-08-27

New guidelines aim to increase accuracy in precision medicine research

A consortium of 23 experts has developed guidelines to improve how research in precision medicine is reported and translated into clinical practice. The guidelines are published in Nature Medicine.Photo: iStock/xubingruo. Precision medicine seeks to reduce errors and improve accuracy in medical and health recommendations, but better evidence is needed to fulfil its potential. An international cons

https://www.medicine.lu.se/article/new-guidelines-aim-increase-accuracy-precision-medicine-research - 2025-08-27

Injectable heart stimulator for emergency situations

In animal studies, researchers have developed an injectable cardiac stimulator for emergency situations. The illustration shows how the injectable heart stimulator is supposed to work when fully developed and tested. Figure: created with biorender.com. By injecting a solution of nanoparticles around the heart, a temporary heart stimulator self-assembles, which can correct heart arrhythmia in emerg

https://www.medicine.lu.se/article/injectable-heart-stimulator-emergency-situations - 2025-08-27

Faster detection of dangerous infections

Johan Malmström, Erik Hartman and Artur Schmidtchen have developed a new innovative technique for peptide analysis that identifies new and better biomarkers for safer diagnostics in inflammation and infection. Foto Åsa Hansdotter In an infection, there are tens of thousands of peptides that provide a wealth of information about which bacteria have caused the infection and how severe it is. A resea

https://www.medicine.lu.se/article/faster-detection-dangerous-infections - 2025-08-27

No benefits from 24-hour compared with 15-hour oxygen therapy

Foto: iStock/kali9 There were no differences in quality of life, symptoms, hospital admissions or mortality between a group of patients with pulmonary disease and low oxygen levels in the blood that received oxygen therapy at home for 24 hours a day, and a group that received the same therapy for 15 hours a day, according to a study from Lund University in Sweden. “This has considerable significan

https://www.medicine.lu.se/article/no-benefits-24-hour-compared-15-hour-oxygen-therapy - 2025-08-27

Researchers reprogram tumor cells into cancer-fighting immune cells in living beings

Researchers are developing a new cancer immunotherapy that reprograms cancer cells into dendritic cells using an adenoviral vector. The image shows how this new approach, tested In preclinical studies, works. Image credit: Joana Carvalho. Researchers at Lund University are developing a new type of gene therapy that reprograms cancer cells within tumors into immune cells that can help the immune sy

https://www.medicine.lu.se/article/researchers-reprogram-tumor-cells-cancer-fighting-immune-cells-living-beings - 2025-08-27

He won the regional heat of the researcher Grand Prix – now heading for the national contest in Stockholm

PhD student Luís Oliveira drew resounding applause for his presentation on how he reprograms cancer cells. Photo: Bodil Malmström. By describing his research as a battle between good and evil and likening himself to a hacker who attacks cancer cells to make them kind, PhD student Luís Oliveira took home the win in this year's Research Grand Prix. It is a competition in presentation technique for r

https://www.medicine.lu.se/article/he-won-regional-heat-researcher-grand-prix-now-heading-national-contest-stockholm - 2025-08-27

Defective sperm doubles the risk of preeclampsia

Aleksander Giwercman and Amelie Stenqvist (Photo: Åsa Hansdotter) For the first time, researchers have linked specific frequent defects in sperm to risk of pregnancy complications and negative impacts on the health of the baby. The study from Lund University in Sweden shows that high proportion of father’s spermatozoa possessing DNA strand breaks is associated with doubled risk of preeclampsia in

https://www.medicine.lu.se/article/defective-sperm-doubles-risk-preeclampsia - 2025-08-27

New method enables identification of mutations in sperm

Men produce hundreds of millions of sperm every day, which means that the male germ cells are constantly undergoing cell division, increasing the risk of harmful mutations.Photo: iStock/Shidlovski It has previously been difficult to identify DNA mutations in sperm, as these changes are rare, and most sequencing techniques have a large margin of error. Now a research study led from Lund University,

https://www.medicine.lu.se/article/new-method-enables-identification-mutations-sperm - 2025-08-27

”Success makes it difficult to quit”

Kári Stefánsson, Professor at the University of Iceland and CEO of deCODE genetics, has been awarded the Eric K. Fernström foundation Grand Nordic Prize, Lund University. Photo: JG/deCODE genetics A career in science was not on the map for Kári Stefánsson, who aspired to become a writer. But life took another road and the return to Iceland almost three decades ago marked the start of a journey tha

https://www.medicine.lu.se/article/success-makes-it-difficult-quit - 2025-08-27

New precision medicine approach helps detect subgroups of people with obesity at high risk of diabetes and heart disease

Obesity is a common cause of diabetes, heart disease and early death, but risk differs greatly from one person to the next. Photo: iStock/Suriyawut Suriya Obesity is a common cause of diabetes, heart disease and early death, but risk differs greatly from one person to the next. In work led by researchers at Lund University in Sweden as part of the Innovative Medicine Initiative project SOPHIA, a p

https://www.medicine.lu.se/article/new-precision-medicine-approach-helps-detect-subgroups-people-obesity-high-risk-diabetes-and-heart - 2025-08-27