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The accumulation of amyloid-β42 fibrils is a hallmark in patients with Alzheimer's disease. The small heat-chock protein αB-crystallin is known to co-exist with amyloid-β42 fibrils and prevent amyloid fibril formation. Amyloid-β42 fibrils arise and expand through different mechanisms of nucleation, however the targeted mechanism by αB-crystallin is yet to be determined. The aim of this project

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Ideellt engagemang utgör en central del av det svenska förenings- och studentlivet, där många studenter lägger betydande tid och energi på oavlönat arbete vid sidan av sina studier. Trots avsaknaden av ekonomisk ersättning fortsätter detta engagemang att vara både omfattande och långvarigt, vilket väcker frågor om vilka faktorer som driver studenter att engagera sig och vad som gör att engagemangeVoluntary engagement is a central aspect of Swedish student life, where many students invest significant time and energy in unpaid work alongside their studies. Despite the absence of financial compensation, such engagement remains both extensive and long-lasting. We aim to answer questions such as, what motivates students to participate and what factors contribute to sustaining their involvement

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Håldäckselement i betong är ett vanligt förekommande byggelement i Nordeuropa. Det är materialeffektiva element som tillverkas i fabrik med förspänd armering i underkant och ihåliga kanaler centrerat i tvärsnittet. Deras utformning och låga egenvikt bidrar till att möjliggöra långa spännvidder och flexibla planlösningar. Metoden för statisk dimensionering och lastkapaciteter finns dokumenterat och

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Byggsektorn står för en betydande andel av klimatutsläppen, vilket gör att både Boverket och EU har föreslagit nya förordningar och regler för mer hållbara alternativ gällande byggnadsmaterial. Där biobaserade byggnadsmaterial kan anses som ett alternativ jämfört med konventionella material. Dessa material, såsom träfiber- och linfiberisolering har potential att minska klimatpåverkan genom att lagThe construction sector accounts for a significant share of greenhouse gas emissions, which has led Boverket and the EU to propose new regulations and guidelines for more sustainable building materials. Biobased construction materials are considered a viable alternative to conventional materials. These materials, such as wood- and flax fibre insulation have the potential to reduce climate impa

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This study aims to investigate how social media trends affect international trade through a study on the relationship between the global matcha tea trend and Japanese green tea exports. The study is performed in two steps, due to limitations in social media data access. Firstly, a time-series regression is used to analyse the relationship between global TikTok views and Google search intensity for

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Many insects have a behavioral need for the rapid detection of small moving visual targets. In dragonflies and flies, Small Target Motion Detector (STMD) neurons have been found to fill this function, but observations in Hymenopterans raise questions of whether similar neurons are present. In high order variants of these neurons, predictive response gain modulation thought to be driven by dendriti

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This thesis examines exchange-rate pass-through (ERPT) to food inflation in Ghana with a focus on domestic transmission channels. Using monthly data, it estimates dynamic reduced-form equations for food inflation and for a set of producer,logistics, transport, and energy-related cost measures. The results show that exchange-rate depreciation passes through meaningfully to food inflation over sever

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This thesis presents a scoping review of academic literature on the intersection of religion, spirituality, and Indigenous worldviews with climate change adaptation. While adaptation research has traditionally emphasised technical, institutional, and financial dimensions, the cultural and spiritual dimensions shaping community responses remain underexplored. To address this gap, the review systema

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Increasing numbers of species face long-term population declines as a consequence of human activities, and these pressures are expected to intensify under a changing and warming climate. Ground-nesting birds in agricultural landscapes are particularly vulnerable, including the Montagu’s harrier (Circus pygargus), which has declined across Europe due to intensive modern agriculture combined with th

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Detailed atomic structures are key to understand and evaluate catalytic activity, ligand binding affinities and many other properties. Neutron crystallography is a popular method for deriving structures of proteins. Unfortunately, the experimental data is typically not enough to settle the exact position of all atoms. Therefore, empirical restraints are employed to ensure that the final structures

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This thesis evaluates the ability of three hand-calculation models for estimating overpressure from hydrogen vapour cloud explosions. The models were the TNT, TNO and OHVE models. The aim was to assess their performance in realistic release environments and identify their strengths and limitations. Model predictions were validated against experimental data from three experimental setups: a refuell

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Kanarieöarna, en ögrupp i Atlanten som tillhör Spanien och bildades för cirka 25 miljoner år sedan, har en komplex geologisk historia präglad av intensiv magmatisk aktivitet från en underliggande så kallad hotspot. Under hotspoten har extraordinärt varmt mantelmaterial transporterats upp till basen av litosfären som delvis har smält upp. Teneriffa, en av de mest välkända öarna i ögruppen, formadesThe Canary Islands, an archipelago in the Atlantic Ocean belonging to Spain and formed about 25 million years ago, have a complex geological history characterized by intense magmatic activity from an underlying so-called hotspot. Under the hotspot, extraordinarily hot mantle material has been transported up to the base of the lithosphere, which has partially been melted. Tenerife, is one of the be

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Nepal ligger i ett av världens mest jordbävningsutsatta områden, och jordbävningen i Gorkha 2015 visade tydligt hur sårbara murverksbyggnader utan ingenjörsmässig dimensionering kan vara. I återuppbyggnadsarbetet har interlocking Compressed Sta- bilised Earth Blocks (CSEB) lyfts fram som ett möjligt alternativ till traditionellt murverk av bränt lertegel. Detta eftersom systemet både kan vara mer Nepal is located in one of the most seismically active regions in the world, and the 2015 Gorkha earthquake clearly demonstrated the vulnerability of non-engineered masonry buildings. In the reconstruction efforts following the earthquake, interlocking Com- pressed Stabilised Earth Blocks (CSEB) have been highlighted as a potentially more seismically robust and at the same time more sustainable al

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This thesis conducts a semiotic study of British colonial stamps produced between 1890 and 1960. The main focus is the stamp's message and ideology, understood within the theoretical framework of Roland Barthes and complemented with postcolonial theory by Anne Kaplan and John MacKenzie. The study concludes that two main mythologies can be constructed by analysing the samples, one regarding the

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This thesis examines how the architecture of Landskrona Konsthall is experienced. Building on a formalist analysis, it investigates two distinct phenomenological perspectives, Wölfflin’s concept of spatial forces and Rasmussen’s emphasis on sensory perception. Methodologically, the study combines reading of theory with on-site field observations, in which visual and sensory impressions are documen

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Denna uppsats analyserar hur agentbaserad e-handel ska klassificeras inom ramen för EU:s mervärdesskattesystem, med fokus på leveranser av varor. Agentbaserad e-handel innebär att konsumenter använder AI-agenter för att söka efter, välja ut och i vissa fall genomföra köp av varor genom ett AIgränssnitt. Uppsatsen undersöker vem som utgör beskattningsbar person, hur leverantörens tjänst ska karaktäThis thesis examines the EU VAT classification of agentic commerce in relation to goods, with particular focus on the conditions under which deemed supplier treatment may arise. Agentic commerce refers to the use of AI agents to search for, select, and in some configurations complete purchases of goods on behalf of a user through an AI interface. The thesis asks who qualifies as a taxable person,

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A shortage of pediatric heart surgeons across the world limits the available surgical interventions, leading to long wait times and higher risk of mortality. The use of robotic surgery and its advantages may help address this issue, and the Collaborative Articial Intelligence Sur- gical Assistance-project is a starting point to develop an autonomous robotic surgical assistant. However, the video f

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Despite its importance, rural groundwater quality in Rwanda remains insufficiently monitored. This study aimed to investigate the groundwater quality, its health implications as well as how management can be improved to reduce the health risks of rural boreholes in the Nyagatare district in Rwanda. In total 61 boreholes were visited and 48 groundwater samples were collected. Analysis was conducted

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The aim of this project was to explore battery enclosures, specifically for e-scooter batteries, and whether additive manufacturing can be used to enhance existing designs. Furthermore, FEM and topology optimization were explored as tools for optimizing these designs. A modified Double Diamond approach was used as a guideline for the project. The modified version enters a prolonged optimization p

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Genom Bohuslän, mellan Strömstad och Göteborg, löper en järnväg. En järnväg som heter Bohusbanan. En järnväg som en gång i tiden var en symbol för framtidstro och utveckling. Banans praktfulla stationshus, de första som välkomnar en och den sista som vinkar adjö vid ett besök till en av de många orterna längs järnvägen, står idag som barriärer till samhällena de tillhör. Byggnaderna som en gång vaThrough Bohuslän, between Strömstad and Gothenburg, runs a railway. A railway called Bohusbanan. A railway that was once a symbol of optimism and progress. The line’s grand station buildings—the first to welcome and the last to bid farewell to visitors of the many towns along the route—now stand as barriers to the communities they belong to. Buildings that were once open, public, social spaces own