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PURPOSE: Major hurdles in oXHTx are the delayed xenograft rejection, the early perioperative cardiac xenograft dysfunction (PCXD) and the pig heart overgrowth, which were solved in this study with a costimulation blockade, a new non-ischemic cold preservation and a growth inhibition by anti-proliferative drugs. Aim was to achieve a 90-days-survival of minimal 60% (6 of 10 baboons) in this life-sup
The global polarization of the Λ and Λ hyperons is measured for Pb-Pb collisions at sNN=2.76 and 5.02 TeV recorded with the ALICE at the Large Hadron Collider (LHC). The results are reported differentially as a function of collision centrality and hyperon's transverse momentum (pT) for the range of centrality 5-50%, 0.5
The ATLAS detector at the Large Hadron Collider reads out particle collision data from over 100 million electronic channels at a rate of approximately 100 kHz, with a recording rate for physics events of approximately 1 kHz. Before being certified for physics analysis at computer centres worldwide, the data must be scrutinised to ensure they are clean from any hardware or software related issues t
The Sagittarius dwarf spheroidal galaxy is in an advanced stage of disruption but still hosts its nuclear star cluster (NSC), M54, at its center. In this paper, we present a detailed kinematic characterization of the three stellar populations present in M54: Young metal-rich (YMR); intermediate-age metal-rich (IMR); and old metal-poor (OMP), based on the spectra of 6500 individual M54 member stars
In this study, we explore whether first language (L1) attrition affects the use of prosodic cues in anaphora resolution. 18 late Italian–Swedish bilinguals completed a speech production task in L1 Italian, wherein we measured the inter-clausal pause duration and the pronoun’s degree of prosodic prominence. They also completed a control interpretation task, wherein we analysed response preferences,
Employing the heuristic of intersectionality, this study analyzes household effects and responses to water shortage in Gaborone, Botswana, focusing on residents’ adaptive capacity and vulnerability. Using data collected through qualitative interviews, we find that households from all socio-economic backgrounds face various effects from water shortage and use numerous strategies to reduce exposure
Adaptation is becoming increasingly significant for public policy and practice in dealing with climate change-related risks and achieving sustainable development. Consequently, the exploration of different ways of assisting successful adaptation has brought under scrutiny the different lifestyles of communities all around the world. Most frameworks adopted to understand adaptation among societies
The countries in the Sahel are undergoing rapid changes due to a mixture of demographic, ecological, and economic transformations. Rural livelihoods in these countries are predominantly engaged in agriculture, which is a foundational component of both food security and the general economy. The relationships between ongoing socio-economic transformation and the agricultural sector are clearly impor
Policy (or political) entrepreneurship (PE) is an actor-based framework to examine and understand policy change. Rooted in Kingdon’s (1984/2003) Multiple Streams approach (MSA), the policy entrepreneur is defined as “a special kind of actor, embedded in the sociopolitical fabric, who is alert to opportunities and acts upon them; he or she amasses coalitions for the purpose of effecting change in
We all need to contribute to a more sustainable development – a fact that has become quite clear observing extreme weathers and diminishing fossil fuel sources. In line with the 12 Principles of Green Chemistry [1], (recommending the use of safer solvents, catalysed reactions, energy efficient processes and renewable feedstocks), research within the SuReTech program aims at developing technologies
With more and more digital collections of various information resources becoming available, also increasing is the challenge of assigning subject index terms and classes from quality knowledge organization systems. While the ultimate purpose is to understand the value of automatically produced Dewey Decimal Classification (DDC) classes for Swedish digital collections, the paper aims to evaluate th
Despite uneventful primary surgery, patients with cleft palate may experience velopharyngeal insufficiency (VPI) and hypernasal speech. Videoradiography of velopharynx is a commonly used method to visualize velopharyngeal function and a velopharyngeal flap is often used to counteract VPI. The aim of this study was to investigate whether the frontal projection on videoradiography plays a role in th
Background: Quantified terminal ileal motility during magnetic resonance enterography (MRE) has been suggested to be used as a biomarker of Crohn's disease (CD). The aim of the present study was to evaluate this method in clinical practice. Methods: Healthy volunteers and all consecutive patients referred to MRE during a 2-year period were asked to participate and complete the Irritable Bowel Synd
Purpose: To compare MR-based fatty acid composition (FAC) quantification methods against the gold standard technique, gas chromatography (GC), with comparison of a free and a constrained signal model. The FAC was measured in the healthy and edematous legs of lymphedema patients. Methods: In vivo MRS and MRI data were acquired from 19 patients at 3 T. Biopsies were collected from subcutaneous adipo
Objectives: To study effects of the introduction of pneumococcal conjugate vaccines (PCV) on the interspecies dynamics of Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis in preschool children with respiratory tract infection. Methods: Nasopharyngeal samples from children aged ≤6 years with upper respiratory tract infection (n = 14 473) in South Sweden were analysed durin
Reflective practice is seen as a method for professional growth and lasting learning outcomes, but what this means in the context of Higher Music Education (HME) has not received sufficient attention. This paper explores how reflection is ontologised and justified as part of performing musicians’ education. The data utilised derive from a comprehensive project investigating how processes of academ
The prevalence of type 2 diabetes (T2D) is rapidly increasing worldwide. Obesity, physical inactivity and ageing increase the risk of T2D. Epigenetic modifications can change due to environmental exposures and may thereby predispose to disease. This review aims at summarizing recent advances in epigenetics related to T2D, with a special focus on impaired insulin action and secretion in humans. The
In the implementation of post-quantum primitives, it is well known that all computations that handle secret information need to be implemented to run in constant time. Using the Fujisaki-Okamoto transformation or any of its different variants, a CPA-secure primitive can be converted into an IND-CCA secure KEM. In this paper we show that although the transformation does not handle secret informatio
