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Auoxo3 is a gold(iii) compound endowed with cytotoxic activity towards a variety of malignant cells. Encapsulation of Auoxo3 within horse spleen ferritin (Ft) improves the selectivity of the gold compound towards cancer cells over normal cells. In the current work, the changes in protein expression are presented in response to MCF-7 stimulation with Auoxo3-encapsulated Ft versus the free Au(iii) c
UV-A radiations are known to induce cellular oxidative stress, leading to premature skin aging. Consumption of açai fruit (Euterpe oleracea Martius) is known to have many health benefits due to its high level of antioxidants. Herein, we analyzed the ability of phenolic compounds extracted from this fruit to attenuate UV-A-induced oxidative stress in immortalized fibroblast. A methanol/water açai e
Aim: A Pt(II)-terpyridine compound, bearing two piperidine substituents at positions 2 and 2′ of the terpyridine ligand (1), is highly cytotoxic and shows a mechanism of action distinct from cisplatin. 1 has been incorporated within the ferritin nanocage (AFt). Materials & methods: Spectroscopic and crystallographic data of the Pt(II)-AFt nanocomposite have been collected and in vitro anticanc
Marine microorganisms represent a reservoir of new promising secondary metabolites. Surface-active proteins with good emulsification activity can be isolated from fungal species that inhabit the marine environment and can be promising candidates for different biotechnological applications. In this study a novel surface-active protein, named Sap-Pc, was purified from a marine strain of Penicillium
X-ray free electron laser (XFEL) microcrystallography and synchrotron single-crystal crystallography are used to evaluate the role of organic substituent position on the optoelectronic properties of metal–organic chalcogenolates (MOChas). MOChas are crystalline 1D and 2D semiconducting hybrid materials that have varying optoelectronic properties depending on composition, topology, and structure. W
Layered transition metal dichalcogenides (TMDs) stabilize in multiple structural forms with profoundly distinct and exotic electronic phases. Interfacing different layer types is a promising route to manipulate TMDs' properties, not only as a means to engineer quantum devices but also as a route to explore fundamental physics in complex matter. Here we use angle-resolved photoemission (ARPES) to i
The encapsulation of Pt and Au-based anticancer agents within a protein cage is a promising way to enhance the selectivity of these potential drugs. Here a cytotoxic organometallic compound containing platinum(II) and gold(I) has been encapsulated within a ferritin nanocage (AFt). Inductively plasma coupled mass spectrometry data, collected to evaluate the amount of Pt and Au within the cage, indi
I rättsfallet NJA 2024 s. 564 har Högsta domstolen avgjort ett mål rörandesexuellt ofredande. En lärare hade under en lektion yttrat ”oj vilka stora bröstdu fick nu” till sin femtonåriga elev. Uttalandet hade fällts i anslutning till attmålsäganden provat ett tyngdlyftarbälte. Högsta domstolen ogillade åtaleteftersom uttalandet visserligen hade varit opassande och olämpligt, men intekunde ”anses h
Small routines and ingrained cultural reflexes as well as micro-rituals form an often unnoticed or ignored flow in everyday life. They acquire their power by being taken for granted and embodied. In situations of conflict, crisis or change, they may suddenly be noticed and become problematic. This chapter looks at how moves, affect, sensations and stuff interact in the making and unmaking of routi
Mars has long been a source of inspiration, imagination and, lately, aspiration for many. It has generated a breadth of beliefs and ideas, as well as hope for a bright future there. However, the red planet will never offer a fresh start: we would carry with us some of our culture and our politics. Our future there would remain connected to Earth’s history, particularly human history. In the presen
Mars science fiction (SF) has interacted with Mars science ever since the advent of modern science, and has largely influenced public perceptions of the red planet and its exploration. In this chapter, it is argued that it has not only shaped numerous (mis)conceptions about the possibilities of indigenous Martian life, eventual human settlement and its challenges, but that it also has a large outr
The aim of this study was to explore how people with impairments perceived the accessibility of information regarding the COVID-19 pandemic in Sweden and what improvements they suggest to ensure accessibility of information in future societal crises. The study had a descriptive design, involving interviews and focus group discussions with people with impairments and their representative organisati
Food packaging is one of the most important strategies to prevent food damage or spoilage during storage and the supply chain. Among various food types, seafood, a high-value product, is particularly vulnerable to post-harvest quality loss and microbial contamination during storage. Although current plastic-based packaging materials are durable, they pose a serious threat to the environment. There
Background: The Organ Care System and Non-ischemic Heart Preservation methods have emerged as significant advancements in heart transplantation, designed to mitigate ischemic injury and extend preservation times. However, their high costs and logistical complexities necessitate strategic utilization. Methods: We evaluated data from 83,761 heart transplants registered in the International Society f
Abstract: Background/Objectives: Vitamin K-dependent proteins (VKDPs) all commonlypossess specially modified γ-carboxyglutamic acid residues created in a vitaminK-dependent manner. Several liver-derived coagulation factors are well characterisedVKDPs. However, much less is known about extrahepatic VKDPs, which are more diversein their molecular structures and functions, and some of which have beenBackground/Objectives: Vitamin K-dependent proteins (VKDPs) all commonly possess specially modified γ-carboxyglutamic acid residues created in a vitamin K-dependent manner. Several liver-derived coagulation factors are well characterised VKDPs. However, much less is known about extrahepatic VKDPs, which are more diverse in their molecular structures and functions, and some of which have been impli
Working from anywhere, often associated with digital nomadism, is a growing trend that blurs the boundaries between work and leisure, with individuals choosing to work from tourist destinations. The phenomenon has caught the attention of academics, who mainly focus on the lifestyle aspects of digital nomadism. However, destination management organizations, as well as the tourism and hospitality in
