This white paper presents a comprehensive biobanking framework developed at the European Cancer Moonshot Lund Center that merges rigorous sample handling, advanced automation, and multi-omic analyses to accelerate precision oncology. Tumor and blood-based workflows, supported by automated fractionation systems and standardized protocols, ensure the collection of high-quality biospecimens suitable

Fires in buildings present life-threatening scenarios where rapid decision-making and timely evacuation are paramount. Significant advancements in understanding evacuation decision-making have been made, though little research addresses the role of memory in this process. Memory plays a crucial role in how individuals perceive, interpret, and respond to information which, during fire evacuation, c

This contribution investigates the nexus of legal and economic dimensions in integrating sustainability enhancements into the assessment of anticompetitive agreements under Article 101(3) TFEU, particularly in light of the Commission’s recent Guidelines on Horizontal Cooperation. It is demonstrated that whilst the narrative of market failure at large, and the concept of sustainability failure spec

The Restricted Syndrome Decoding Problem (RSDP) is a variant of the well-known syndrome decoding problem. It has been recently turned into a post-quantum signature scheme named CROSS by Baldi et al.. It is a scheme highlighted for being computationally friendly and providing a compact signature and public key size. This paper investigates an Oracle-based definition of the RSDP that has already pro

Companies increasingly rely on web-based idea management systems (IMS) to source innovative ideas from their employees and external contributors. While existing research emphasizes the critical role of expert feedback in shaping ideators' subsequent contributions, there remains a limited understanding of how various types of feedback—and their interplay—affect future idea success. Grounded in feed

Mobile stroke units (MSUs), which are specialized ambulances equipped with a brain imaging device and staffed with trained healthcare personnel, have the potential to provide rapid on-site diagnosis and treatment for stroke patients. However, efficient access to prehospital stroke care requires optimizing the placement of MSUs. The MSU allocation problem has been previously solved using a traditio

Flyxensjön, som utgör källan till avrinningsområdet, har god vattenkvalitet. Men när floden rinner vidare och korsar flera torvmarker försämras vattenkvaliteten avsevärt, vilket understryker det akuta behovet av att undersöka påverkansfaktorerna i detta avrinningsområde. Denna studie undersöker de rumsliga och tidsmässiga variationerna i vattenkvaliteten längs Kåtån, från Flyxensjön till sjön KöseThe Lake Flyxen, as the headwater of the watershed, maintains good water quality. However, as the river flows downstream and intersects several peatlands, the water quality deteriorates significantly, highlighting the urgent need to investigate the influencing factors in this watershed. This study examines the spatial and temporal variations in water quality along the Kåtån River from Flyxen Lake

Open-source microscopes like the PlanktoScope have recently gained attention as affordable tools for studying plankton diversity. Compared to commercial systems, they are low-cost, modular, and suitable for both scientific research and citizen science projects. In this study, we assembled and tested the PlanktoScope v.2 system to evaluate its performance in identifying and quantifying freshwater a

This dissertation explores the socioeconomic impacts of mine closures in Canada, focusing on the vulnerabilities that arise within local economies and the political economy implications of industrial changes. Through a combination of historical, quantitative, and qualitative analyses, the research provides a comprehensive understanding of the effects of mine closures on employment, municipal finan

Background: Combined CDK4/6 inhibitor (CDK4/6i) and endocrine therapy significantly improve the outcome of patients with advanced estrogen receptor-positive (ER+) breast cancer. However, resistance to this treatment and disease progression remains a major clinical challenge. High expression of the receptor tyrosine kinase REarranged during Transfection (RET) has been associated with resistance to

A new microphysical treatment that includes aerosol–cloud interactions and secondary ice production (SIP) mechanisms is implemented in the convection scheme of the Community Atmosphere Model, version 6 (CAM6). The approach is to embed a 1D Lagrangian parcel model in the bulk convective plume of the existing deep convection parameterization. Aerosol activation, growth processes including collision/

Introduction: Knee pain increases the risk of developing chronic widespread pain (CWP) and knee osteoarthritis (KOA). The prevalence of CWP and KOA has increased, and there is a need for early prevention. Therefore, the aim was to examine the associations of health-related quality of life (HRQoL) and lifestyle habits with chronic pain at a two-year follow-up in individuals with knee pain. Methods:

The advancement of disease-modifying treatments (DMTs) for Alzheimer's disease (AD), along with the approval of three amyloid-targeting therapies in the US and several other countries, represents a significant development in the treatment landscape, offering new hope for addressing this once untreatable chronic progressive disease. However, significant challenges persist that could impede the succ

During the evolution of parasites, co-speciation and host-range expansion are thought to play roles in establishing associations with hosts, while sorting events can lead to dissolution of those associations. To address the roles of these processes, we focus on avian haemosporidian parasites infecting hosts of the intensively studied great tit species complex. We estimated the phylogeography of li

In situ catalysis studies typically correlate catalytic function and majority surface structures, but neglect that difficult-to-detect minority structures might govern catalysis. Here we use an oscillating CO:O2 gas composition to drive structural oscillations on a catalytically active Pd(100) surface and collect X-ray photoelectron spectroscopy data at high measurement frequency to demonstrate th