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Calreticulin is a highly conserved multifunctional protein implicated in many different biological systems and has therefore been the subject of intensive research. It is primarily present in the endoplasmatic reticulum where its main functions are to regulate Ca2 + homeostasis, act as a chaperone and stabilize the MHC class I peptide-loading complex. Although several high-resolution structures of
Objective Among primary prevention patients with heart failure receiving cardiac resynchronisation therapy (CRT), the impact of additional implantable cardioverter defibrillator (ICD) treatment on outcomes and its interaction with sex remains uncertain. We aim to assess whether the addition of the ICD functionality to CRT devices offers a more pronounced survival benefit in men compared with women
We establish Lieb–Thirring power bounds on discrete eigenvalues of Jacobi operators for Schatten class perturbations under very general assumptions. Our results apply, in particular, to perturbations of reflectionless Jacobi operators with finite gap and Cantor-type essential spectrum.
In recent years, Scandinavian scholars have shown an increasing interest in German research on confessionalisation in early modern Europe. In this article, I set out the research topic for a Scandinavian audience and suggest how best to use the concept of confessionalisation when working with Scandinavian sources. The concept of confessionalisation focuses on the creation of the three main confess
Domain-continuous visibility determination algorithms have proved to be very efficient at reducing noise otherwise prevalent in stochastic sampling. Even though they come with an increased overhead in terms of geometrical tests and visibility information management, their analytical nature provides such a rich integral that the pay-off is often worth it. This paper presents a time-continuous, prim
Detta är en monografi skriven i samarbete med litteraturvetaren Ingemar Oscarsson. Boken bygger på ett opublicerat franskt 1600-tals manuskript, ms. 1143, som bär titeln Mémoires d’un voyage fait dans les pays septentrionaux en l’an M.D.C.LXIII. Originalmaterialet är ett inbundet dokument i kvartoformat på 280 handskrivna sidor.
Detta är en monografi som förenar den filologiska disciplinens traditionella infallsvinklar (textedition, översättning, litterära och lingvistiska analyser) med modern litteraturteori. Boken ingår i Ellerströms akademiska serie Eureka och innehåller en kritisk textedition av den fornfranska berättelsen Li Lais de l’ombre av Jean Renart (962 verser). Texten är etablerad med utgångspunkt i ett av de
New fusionless devices are being developed to get over the limits of actual spinal surgical treatment, based on arthrodesis. However, due to their recentness, no standards exist to test and validate those devices, especially concerning the wear. A new tribological first approach to the definition of an in vitro wear protocol to study wear of flexible and sliding spinal devices is presented in this
Detta är en ny textkritisk utgåva av en unik version av hjältedikten Théséus de Cologne som ingår som en del av en krönika om hertigarna från Savojen. Det ingår också en tolkning av verkets tillblivelse och betydelse i den historiska och intertextuella kontext som författaren befann sig i under skrivandet.
The porcine model is frequently used during development and validation of new spinal devices, because of its likeness to the human spine. These spinal devices are frequently composed of pedicle screws with a reputation for stable fixation but which can suffer pullouts during preclinical implantation on young animals, leading to high morbidity. With a view to identifying the best choices to optimiz
Most acetabular cups implanted today are press-fit impacted cementless. Anchorage begins with the primary stability given by insertion of a slightly oversized cup. This primary stability is key to obtaining bone ingrowth and secondary stability. We tested the hypothesis that primary stability of the cup is related to surface roughness of the implant, using both an experimental and a numerical mode
PURPOSE: We evaluated the biomechanical strength of two all suture anchors (ASA) of reduced diameter (1.4 mm) and compared them with the standard screw anchor (SA) with larger diameter (5.5 mm) used in rotator cuff tears. METHODS: We conducted 30 uniaxial vertical pullout tests using Material Testing System Instron 5566A until failure of the anchorage defined as rupture of the threads or anchor or
We have tracked the structural evolution of the monoolein bicontinuous cubic phase under in meso crystallogenesis conditions. Significantly, all measurements have been carried out in situ within a crystallisation plate reproducing the exact conditions during a crystallisation trial. The structure of the MO cubic phase, doped with a small concentration of amyloid-beta peptide, was measured 1 day, 5
AIMS AND OBJECTIVES: An in-depth exploration of self-efficacy among heart transplant recipients by means of Bandura's self-efficacy theory.BACKGROUND: An essential component of chronic illness management is self-management, which refers to activities carried out by people to create order, structure and control in their lives. Self-efficacy is an important aspect of self-management, which seems to
AbstractAim The aim of this thesis was to evaluate the treatment and follow-up of patients undergoing hypospadias surgery at the Department of Plastic and Reconstructive Surgery, Skåne University Hospital, Malmö, in an attempt to improve the overall care of these patients. It also aimed to investigate the tissue properties of the urethral plate and deep chordee in hypospadias patients with signifiAbstractAim The aim of this thesis was to evaluate the treatment and follow-up of patients undergoing hypospadias surgery at the Department of Plastic and Reconstructive Surgery, Skåne University Hospital, Malmö, in an attempt to improve the overall care of these patients. It also aimed to investigate the tissue properties of the urethral plate and deep chordee in hypospadias patients with signifi
Innovation is widely recognized as an important variable to create competitive advantage and drive economic growth. Innovation is also a relatively vague concept, but the absence of it results in stagnation and loss of competitive behaviors. Innovation capability is the ability to be innovative, and is a characteristic of individuals as well as organizations. The issue with learning and executing
