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Heterozygous mutations in GATA2 underlie different syndromes, previously described as monocytopenia and mycobacterial avium complex infection (MonoMAC); dendritic cell, monocytes, B- and NK lymphocytes deficiency (DCML); lymphedema, deafness and myelodysplasia (Emberger syndrome) and familiar myelodysplastic syndrome/acute myeloid leukemia (MDS / AML). Onset and severity of clinical symptoms vary

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The purpose of this study was to derive calibration coefficients (in terms of cps kBq-1) and minimum detectable activities, MDA, (in terms of kBq and corresponding dose rate) for the dual head gamma camera part of an SPECT/CT-instrument when used for in vivo internal contamination measurements in radiation emergency situations. A cylindrical-conical PMMA phantom with diameters in the range of 7-30

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BACKGROUND: During the therapeutic videofluoroscopic examination of swallowing, gradation of bolus volume, texture, and viscosity can be implemented to determine the optimal bolus characteristics in that particular patient. When a thickened liquid is given to a dysphagic patient it is served at room temperature. However, in these patients with a delayed oral and/or pharyngeal stage of swallow, the

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Cancer-associated fibroblasts (CAF) attract increasing attention as potential cancer drug targets due to their ability to stimulate, for example, tumor growth, invasion, angiogenesis, and metastasis. However, the molecular mechanisms causing the tumor-promoting properties of CAFs remain poorly understood. Forkhead box F1 (FoxF1) is a mesenchymal target of hedgehog signaling, known to regulate mese

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This paper describes a driving simulator trial to evaluate driver reactions to a number of alternative information/ warning modes of a multi-modal system for the “safe speed and safe distance” concept. In 2006, eight Human Machine Interaction alternatives, consisting of a combination of visual, haptic and auditory modes were used alternatively to give information/warning to the driver on safe spee

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BACKGROUND: Solutions of iodine contrast media (CM) used for selective coronary arteriography (CA) should have minimal propensity to cause ventricular fibrillation (VF). Commonly used CM for CA are nonionic monomers or dimers. PURPOSE: To compare VF propensity of ready-to-use solutions of one nonionic dimer, iodixanol, and five nonionic monomers, iobitridol, iopamidol, iomeprol, iopromide, and iov

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The dynamical theory of X-ray spectra due to Nozieres and De Dominicis (ND, 1969) is evaluated here numerically for numerous model systems including cases where the core-hole potential possesses a bound state. It is shown that the resulting emission spectra obey the final-state rule rather accurately. An approximate but analytical derivation of this rule is given which provides insight into the me

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The dysfunction of misplaced or dislodged endovascular endoprostheses, may be a serious complication, and endovascular removal may be attempted in some cases.

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Optical absorption spectroscopy is a widely used analytical tool for constituent analysis in many applications. According to the Beer-Lambert law, the transmitted light intensity through a homogeneous medium is an exponential function of the product of the concentration, the total pathlength, and the absorption cross-section of the absorbing substance. By studying the intensity loss at the unique