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Transcriptomic and proteomic profiling classify bladder cancers into luminal and basal molecular subtypes, with controversial prognostic and predictive associations. The complexity of published subtyping algorithms is a major impediment to understanding their biology and validating or refuting their clinical use. Here, we optimize and validate compact algorithms based on the Lund taxonomy, which s
A novel stochastic strategy for solving the problem of optimal power management of multi-microgrid (MMG) systems is suggested in this paper. The considered objectives are minimizing the total cost and emission of the system. The suggested algorithm is applied on a MMG consisting of four microgrids (MG), each including fossil fuel-based generator units, wind turbine (WT), photovoltaic (PV) panel, b
This paper provides reflections on transdisciplinary knowledge coproduction and experimentation processes from sustainability researcher perspectives. It centers on a 5-year period of collaborative research with small- and medium-sized enterprises in an Urban Living Lab in the Swedish craft beer sector. Nine reflections cover a variety of issues and potentials encountered during numerous interacti
Improved agricultural management plays a vital role in protecting soils from degradation in eastern Africa. Changing practices such as reducing tillage, fertilizer use, or cover crops are expected to enhance soil organic carbon (SOC) storage, with climate change mitigation co-benefits, while increasing crop production. However, the quantification of cropland management effects on agricultural ecos
Aquaporin-4 (AQP4) is the predominant water channel in the brain; it is enriched in astrocytic foot processes abutting vessels where it is anchored through an interaction with the dystrophin-associated protein (DAP) complex. Enhanced expression with concomitant mislocalization of AQP4 along astrocyte plasma membranes is a hallmark of several neurological conditions. Thus, there is an urgent need t
Confocal imaging is a well-established method for investigating plant phenotypes on the tissue and organ level. However, many differences are difficult to assess by visual inspection and researchers rely extensively on ad hoc manual quantification techniques and qualitative assessment. Here we present a method for quantitatively phenotyping large samples of plant tissue morphologies using triangul
Digital signatures are widely deployed to authenticate the source of incoming information, or to certify data integrity. Common signature verification procedures return a decision (accept/reject) only at the very end of the execution. If interrupted prematurely, however, the verification process cannot infer any meaningful information about the validity of the given signature. We notice that this
Proximity testing is at the core of sev-eral Location-Based Services (LBS) offered by, e.g., Uber, Facebook, and BlaBlaCar, as it determines closeness to a target. Unfortunately, modern LBS demand not only that clients disclose their locations in plain, but also to trust that the services will not abuse this information. These requirements are unfounded as there are ways to perform proximity testi
Background: Magnetic resonance (MR) safety procedures are designed to allow patients, research subjects and personnel to enter the MR-scanner room under controlled conditions and without the risk to be harmed during the examination. Ferromagnetic objects in the MR-environment or inside the human body represent the main safety risks potentially leading to human injuries. Screening for MR-safety ris
The study aimed to create a pipeline from Monte Carlo simulated projections of a Gate PET system to reconstructed images. The PET system was modelled after the GE Discovery MI (DMI) PET/CT, and the simulated projections were reconstructed with the stand-alone reconstruction software CASToR. Attenuation correction, normalisation calibration, random estimation, and scatter estimation for the simulat
