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The complex interplay of the tumour and immune cells affects tumour growth, progression, and response to treatment. Restorationof effective immune response forms the basis of onco-immunology, which further enabled the development of immunotherapy. Inthe era of precision medicine, pin-pointing patient biological heterogeneity especially in relation to patient-specific immunemicroenvironment is a ne
Accurate train delay prediction is vital for effective railway traffic planning and management as well as for providing satisfactory passenger service quality. Despite significant advances in data-driven train delay predictions, it lacks of a systematic review of studies and unified modelling development framework. The paper reviews existing studies with an explicit focus on synthesizing a structu
In the interactive effects panel data literature information criteria are commonly used to consistently determine which of the estimated principal components factors to include. The present paper shows that the same approach can be applied to factors estimated by taking the cross-sectional averages of the observables, as prescribed by the popular common correlated effects (CCE) approach. This shou
Inter-organisational projects depend on stakeholder interactions and joint decision-making to perform and continually adjust to variations. This paper examines the emergence of transformative resilience (i.e., dynamic project capabilities to pursue fundamentally new strategies and practices) when facing external disruptions. A process-orientated case study was conducted within a culturally diverse
Continuous access to flows of goods and services, such as energy, transport, information, and food, is essential and the basis for functioning modern societies. Hence, they are critical and need to be secured. Mega-trends such as climate change, changing geopolitical environment, hybrid- and cyber threats, and rapid technological advances come with new challenges and emerging threats to securing f
Wild insect pollinators are essential to cultivated and natural ecosystems globally. Today, many pollinator species are declining. One reason is a general lack of flowering habitats at landscape scales. However, urban areas, including private gardens, may provide flowers, and constitute beneficial habitats for pollinators. Here, we evaluate the ecological outcomes of a citizen science campaign run
The structure and organization of a tumor and its microenvironment are often associated with cancer outcomes due to spatially varying molecular composition and signaling. A persistent challenge is to use this physical and chemical spatial organization to understand cancer progression. Here, we present a high-definition infrared imaging–based organizational measurement framework (INFORM) that lever
BACKGROUND: Many children with juvenile idiopathic arthritis (JIA) have autoantibodies, targeting nuclear components (anti-nuclear antibodies, ANA). ANA in JIA is associated with uveitis, an eye inflammation which may cause permanent vision impairment if not detected and treated. However, ANA-testing is neither specific nor sensitive enough to be a clinically reliable predictor of uveitis risk, an
This article discusses the reconfiguration of citizenship education in the Swedish Boy Scout movement, one of the country’s largest civil society organizations, after 1945. Citizenship education was a core feature of scouting since its establishment during the first decades of the twentieth century, with patriotism and practical helpfulness as core tenets. Additionally, an emphasis on hiking and cThis article discusses the reconfiguration of citizenship education in the Swedish Boy Scout movement, one of the country’s largest civil society organizations, after 1945. Citizenship education was a core feature of scouting since its establishment during the first decades of the twentieth century, with patriotism and practical helpfulness as core tenets. Additionally, an emphasis on hiking and c
Wetlands are valuable natural capital and sensitive ecosystems facing significant risks from anthropogenic and climatic stressors. An assessment of the environmental risk levels for wetlands’ dynamic ecosystems can provide a better understanding of their current ecosystem health and functions. Different levels of environmental risk are defined by considering the categories of risk and the probabil
Bidraget visar hur man i retorikutbildning kan stödja studenters livslånga lärande och förmåga till egen kompetensutveckling. Skriftliga reflektioner lyfts fram som ett didaktiskt redskap och samarbete med arbetslivskoordinator som ett sätt att stärka utbildningens relevans och överbrygga gränsen mellan utbildning och yrkesliv.
