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Medication Discrepancies in Discharge Summaries and Associated Risk Factors for Elderly Patients with Many Drugs

BACKGROUND AND OBJECTIVE: Elderly patients are at high risk for medication errors in care transitions. The discharge summary aims to counteract drug-related problems due to insufficient information transfer in care transitions, hence the accuracy of its medication information is of utmost importance. The purpose of this study was to describe the medication discrepancy rate and associated risk fact

The Effects of Frontal Brain Impairment on Fluency : Simple and Complex Paradigms

Neuropsychological measures of fluency require productivity under timed conditions. The current study explored the parameters of fluency paradigms by extending the associational demands of the tasks. Ss with frontal lobe tumors (n = 17) were compared with normal subjects (n = 17) on simple and complex fluency tasks. Complex fluency tasks appeared to be more sensitive to tumor presence than simple

Automated Image-Based Quantification of Neutrophil Extracellular Traps Using NETQUANT

Neutrophil extracellular traps (NETs) are web-like antimicrobial structures consisting of DNA and granule derived antimicrobial proteins. Immunofluorescence microscopy and image-based quantification methods remain important tools to quantitate neutrophil extracellular trap formation. However, there are key limitations to the immunofluorescence-based methods that are currently available for quantif

A direct solver for the phase retrieval problem in ptychographic imaging

Measurements achieved with ptychographic imaging are a special case of diffraction measurements. They are generated by illuminating small parts of a sample with, e.g., a focused X-ray beam. By shifting the sample, a set of far-field diffraction patterns of the whole sample is then obtained. From a mathematical point of view those measurements are the squared modulus of the windowed Fourier transfo

An instrument variable based algorithm for estimating cross-correlated hydrological remote sensing errors

Optimally using multi-source remote-sensing (RS) and/or reanalyzed hydrological products requires knowledge of each product's accuracy and inter-product error cross-correlations. Quadruple collocation (QC) analysis can potentially solve for this error information without the reliance of high-quality ground references. However, QC requires at least three independent products for a variable of inter

A double instrumental variable method for geophysical product error estimation

The global validation of remotely sensed and/or modeled geophysical products is often complicated by a lack of suitable ground observations for comparison. By cross-comparing three independent collocated observations, triple collocation (TC) can solve for geophysical product errors in error-prone systems. However, acquiring three independent products for a geophysical variable of interest can be c

Hydrologic evaluation of TRMM and GPM IMERG satellite-based precipitation in a humid basin of China

Tropical Rainfall Measurement Mission (TRMM) is one of the most popular global high resolution satellite-based precipitation products with a goal of measuring precipitation over the oceans and tropics. However, in recent years, the TRMM mission has come to an end. Its successor, Global Precipitation Measurement (GPM) mission was launched to measure the earth's precipitation structure, with an aim

Spatial evaluation of L-band satellite-based soil moisture products in the upper Huai River basin of China

Using dense soil moisture (SM) measurements in the upper Huai River basin of China, this study evaluated the spatial patterns of L-band satellite-based SM products, including Soil Moisture Active Passive (SMAP) L3, Soil Moisture and Ocean Salinity (SMOS) L3 and the European Space Agency’s Climate Change Initiative (ESA CCI) SM products. The mean difference (MD), root mean squared error (RMSE), unb

The impact of the Madden-Julian Oscillation on hydrological extremes

Extreme climate events such as severe droughts and floods have become more frequent and widespread in the 21st Century. Recent studies have revealed the tele-connections between Madden–Julian Oscillation (MJO) and extreme precipitation over different regions such as South America, India and China. This study investigates the influence of MJO on global extreme dry and wet conditions, and how the st

Enhancing SWAT with remotely sensed LAI for improved modelling of ecohydrological process in subtropics

Vegetation growth in Soil and Water Assessment Tool (SWAT) is a crucial process for quantifying ecohydrological modelling, as it influences evapotranspiration, interception, soil erosion and biomass production. The simplified version of Environmental Policy Integrated Climate (EPIC) in SWAT was originally designed for temperate regions and naturally based on temperature to simulate growth cycles

Pulmonary blood volume index as a quantitative biomarker of haemodynamic congestion in hypertrophic cardiomyopathy

AIMS : The non-invasive assessment of left ventricular (LV) diastolic function and filling pressure in hypertrophic cardiomyopathy (HCM) is still an open issue. Pulmonary blood volume index (PBVI) by cardiovascular magnetic resonance (CMR) has been proposed as a quantitative biomarker of haemodynamic congestion. We aimed to assess the diagnostic accuracy of PBVI for left atrial pressure (LAP) esti

Cardiovascular biomarkers and echocardiographic findings at rest and during graded hypovolemic stress in women with recurrent vasovagal syncope

Introduction: Vasovagal reflex is the most common type of syncope but its etiology is not fully elucidated. Venous return and cardiac output are key in hemodynamic control. The aim of the study was to assess cardiovascular biomarkers and echocardiographic measures at rest and during hypovolemia in women with and without a history of vasovagal syncope. Methods: Fourteen women (aged 18-30) suffering

Prospective virome analyses in young children at increased genetic risk for type 1 diabetes

Viruses are implicated in autoimmune destruction of pancreatic islet β cells, which results in insulin deficiency and type 1 diabetes (T1D)1-4. Certain enteroviruses can infect β cells in vitro5, have been detected in the pancreatic islets of patients with T1D6 and have shown an association with T1D in meta-analyses4. However, establishing consistency in findings across studies has proven difficul

Absence of Islet Autoantibodies and Modestly Raised Glucose Values at Diabetes Diagnosis Should Lead to Testing for MODY : Lessons From a 5-Year Pediatric Swedish National Cohort Study

OBJECTIVE: Identifying maturity-onset diabetes of the young (MODY) in pediatric populations close to diabetes diagnosis is difficult. Misdiagnosis and unnecessary insulin treatment are common. We aimed to identify the discriminatory clinical features at diabetes diagnosis of patients with glucokinase (GCK), hepatocyte nuclear factor-1A (HNF1A), and HNF4A MODY in the pediatric population.RESEARCH D

A polar dinosaur feather assemblage from Australia

Exceptionally preserved Mesozoic feathered dinosaur fossils (including birds) are famous, but recognized from only very few localities worldwide, and are especially rare in the Southern Hemisphere. Here we report an assemblage of non-avian and avian dinosaur feathers from an Early Cretaceous polar (around 70°S) environment in what is now southeastern Australia. The recovered remains incorporate sm

Interval and Consecutive Round Breast Cancer after Digital Breast Tomosynthesis and Synthetic 2D Mammography versus Standard 2D Digital Mammography in BreastScreen Norway

Background: Screening that includes digital breast tomosynthesis (DBT) with two-dimensional (2D) synthetic mammography (SM) or standard 2D digital mammography (DM) results in detection of more breast cancers than does screening with DM alone. A decrease in interval breast cancer rates is anticipated but is not reported. Purpose: To compare rates and characteristics of (a) interval breast cancer in

Do improved pollination services outweigh farm-economic disadvantages of working in small-structured agricultural landscapes? – Development and application of a bio-economic model

Increases in the size of agricultural fields, the loss of permanent green field edges and other semi-natural habitats have accompanied the intensification of agriculture, and are still ongoing. From a farm economic perspective, an increase in field size increases efficiency mainly due to cost savings. However, recent evidence suggests that increases in field size might lead to the loss of ecosyste

Appropriate coronary revascularization can be accomplished if myocardial perfusion is quantified by positron emission tomography prior to treatment decision

Background: Many patients undergo percutaneous coronary intervention (PCI) without the use of non-invasive stress testing prior to treatment. The aim of this study was to determine the potential added value of guiding revascularization by quantitative assessment of myocardial perfusion prior to intervention. Methods and Results: Thirty-three patients (10 females) with suspected or established CAD

A phase-correlated duo-binary waveform generation technique for millimeter-wave radar pulses

We propose a technique for generating millimeter-wave radar waveforms using edge-triggered pulse generator circuits. By synchronizing the chip rate to the oscillation frequency of a binary control signal, a phase shift is introduced in the generated pulses. This way, the millimeter-wave signal can be phase-modulated without the need of additional circuit elements. We show that high-resolution rada