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A personal history of autoimmune diseases is associated with an increased incidence of gastric cancer, but whether they share familial susceptibility is still unknown. The contribution of shared environmental or genetic factors toward the observed familial aggregation has not been determined. We used a few Swedish registers, including the Swedish Multigeneration Register and the Cancer Register, t

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Water flowing through hyporheic river sediments or artificial recharge facilities promotes the development of microbial communities with sediment depth. We performed an 83-day mesocosm infiltration experiment, to study how microbial functions (e.g., extracellular enzyme activities and carbon substrate utilization) are affected by sediment depth (up to 50 cm) and different oxygen concentrations. Re

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The technological evolutions have promoted mobile devices from rudimentary communication facilities to advanced personal assistants. According to the huge amount of accessible data, developing a time-saving and cost-effective method for location-based recommendations in mobile devices has been considered a challenging issue. This paper contributes a state-of-the-art solution for a personalized rec

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Vadose zone oxygen dynamics control all subsurface redox reactions and play a decisive role in maintaining groundwater quality. Although drying and wetting events are common in artificial recharge, their effects on subsurface oxygen distribution are poorly documented. We monitored oxygen concentration in the unsaturated zone in a mid-scale (1 m high) laboratory soil lysimeter, which was subjected

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Determining high-resolution structures of proteins with helical symmetry can be challenging due to limitations in experimental data. In such instances, structure-based protein simulations driven by experimental data can provide a valuable approach for building models of helical assemblies. This chapter describes how the Rosetta macromolecular package can be used to model homomeric protein assembli

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Infiltration through sediments is linked to complex biogeochemical processes occurring at small spatial scales, often leading to a progressive reduction in infiltration rates due to microbial growth and/or mechanical clogging. Unraveling the linkage between microbial dynamics and water infiltration in a heterogeneous medium is of concern in artificial recharge ponds and natural infiltration system

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We provide an approximate analytical solution for the substrate-microbial dynamics of the organic carbon cycle in natural soils under hydro-climatic variable forcing conditions. The model involves mass balance in two carbon pools: substrate and biomass. The analytical solution is based on a perturbative solution of concentrations, and can properly reproduce the numerical solutions for the full non

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Chiral dienes are useful ligands in a number of asymmetric transition-metal-catalyzed reactions. Here, we evaluate the efficiency of 2,5-disubstituted 1,3a,4,6a-tetrahydropentalenes as ligands to rhodium(I). 2,5-Dibenzyl and diphenyl tetrahydropentalenes were synthesized in two steps and resolved, either chromatographically, or through fractional crystallization of diastereomeric rhodium(I) salts.

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At the southern margin of permafrost in North America, climate change causes widespread permafrost thaw. In boreal lowlands, thawing forested permafrost peat plateaus (‘forest’) lead to expansion of permafrost‐free wetlands (‘wetland’). Expanding wetland area with saturated and warmer organic soils is expected to increase landscape methane (CH4) emissions. Here, we quantify the thaw‐induced increa

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Over the last several decades the hydrologically sensitive Boreal Plains ecoregion of Western Canada has experienced significant warming and drying. To better predict implications of land cover changes on evapotranspiration (ET) and future water resources in this region, high resolution light detection and ranging and energy balance data are used here to spatially parameterize the Penman-Monteith

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Spaceborne laser altimetry waveform estimates of canopy Gap Fraction (GF) vary with respect to discrete return airborne equivalents due to their greater sensitivity to reflectance differences between canopy and ground surfaces resulting from differences in footprint size, energy thresholding, noise characteristics and sampling geometry. Applying scaling factors to either the ground or canopy porti

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The Geoscience Laser Altimeter System (GLAS) has the potential to accurately map global vegetation heights and fractional cover metrics using active laser pulse emission/reception. However, large uncertainties in the derivation of data products exist, since multiple physically plausible interpretations of the data are possible. In this study a method is described and evaluated to derive vegetation

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Pseudouridylation (Ψ) is the most abundant and widespread type of RNA epigenetic modification in living organisms; however, the biological role of Ψ remains poorly understood. Here, we show that a Ψ-driven posttranscriptional program steers translation control to impact stem cell commitment during early embryogenesis. Mechanistically, the Ψ “writer” PUS7 modifies and activates a novel network of t

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In the sporadic permafrost zone of northwestern Canada, boreal forest carbon dioxide (CO2) fluxes will be altered directly by climate change through changing meteorological forcing and indirectly through changes in landscape functioning associated with thaw‐induced collapse‐scar bog (‘wetland’) expansion. However, their combined effect on landscape‐scale net ecosystem CO2 exchange (NEELAND), resul