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OBJECTIVES:: Cholecystokinin (CCK)-dependent exocrine pancreatic regulation seems to involve different pathways in different species. The aims were to explore the enteropancreatic reflex in the CCK-mediated regulation of the exocrine pancreas and to evaluate a possible involvement of this reflex in the endocrine insulin release. METHODS:: In anesthetized pigs, CCK-33 in increasing doses (4-130 pmo
Using the configuration interaction technique, the energy spectra of 2s(2)2p(4), 2s2p(5), 2s(2)2p(3)3s, 2s(2)2p(3)3d, configurations of oxygen-like chlorine Cl X have been calculated. The obtained data are used for the evaluation of wavelengths and oscillator strengths of all possible one-electron and two-electron 2s(2)2P(3)3p-2s2p(5) electric dipole transitions. The calculated results are compare
We present a novel method for investigating subsite-substrate interactions of glycoside hydrolases and the determination of the oligosaccharide cleavage point based on the analysis of the hydrolysis products produced in the presence of (18)O-labelled water. Conventional techniques for such determination of the hydrolysis pattern call for the chemical modification of the substrate, whereas the meth
In this paper, I take a closer look at a set of observations concerning word order and co-occurrence restrictions on verb-particle constructions, berefactive double object constructions and resultative constructions in Norwegian. While a particle can co-occur with both a beneficiary DP and a resultative AP, beneficiary DPs and resultatives cannot co-occur at all. I give an analysis in terms of the
All weak traveling wave solutions of the Camassa-Holm equation are classified. We show that, in addition to smooth solutions, there are a multitude of traveling waves with singularities: peakons, cuspons, stumpons, and composite waves.
Western style diets and lifestyles are associated with increasing rates of obesity, diabetes and insulin resistance. Higher circulating insulin levels may modulate cell proliferation and apoptosis either directly or indirectly by increasing the bioactivity of IGF-I and decreasing the bioactivity of some of its binding proteins. The objective of this study was to determine the association of increa
Death-associated protein kinase (DAPK) is a calcium calmodulin-regulated serine/threonine protein kinase involved in ischemic neuronal death. In situ hybridization experiments show that DAPK mRNA expression is up-regulated in brain following a global ischemic insult and down-regulated in ischemic tissues after focal ischemia. DAPK is inactive in normal brain tissues, where it is found in its phosp
Two different approaches to modeling evolving anisotropic material behavior are investigated. The first approach models the evolution of the directionally dependent properties of the material in terms of evolution laws for the director vectors. In the second approach the evolution law for the plastic velocity gradient is enhanced by additional terms. It is shown that both approaches lead to an evo
The success of the identification of the planar dilatation operator of N = 4 SYM with an integrable spin chain Hamiltonian has raised the question if this also is valid for a deformed theory. Several deformations of SYM have recently been under investigation in this context. In this work we consider the general Leigh-Strassler deformation. For the generic case the S-matrix techniques cannot be use
Background: The indications for percutaneous transluminal renal angioplasty (PTRA) in renovascular disease, as well as its benefits, remain a matter of debate. The aim of this study was to evaluate the outcome of angioplasty and to identify risk factors associated with less successful outcomes in patients with atheromatous renal artery stenosis and renal failure of varying degrees. Methods: The re
Objectives: During the last few years, clinical, epidemiological, and pathological evidence has suggested that inherited alpha-1 antitrypsin [AAT] deficiency might play a role in the development of the fibromyalgia syndrome [FMS], probably because of the loss of AAT anti-inflammatory efficacy. The objective of this study was to estimate the prevalence and number of FMS patients, and their AAT phen
We previously demonstrated that secreted proform(s) of the neutrophil serine protease PR3 (proteinase 3) can down-modulate the fraction of normal human colony-forming unit granulocyte-macrophage (CFU-GM) in S-phase, whereas PR3 extracted from mature neutrophils lacks this ability. The objective of this study was to characterize the structural and functional dissociation between secreted proforms a
Linkage disequilibrium in highly selfing organisms is expected to extend well beyond the scale of individual genes. The pattern of polymorphism in such species must thus be studied over a larger scale. We sequenced 14 short (0.5-1 kb) fragments from a 400-kb region surrounding the flowering time locus FRI in a sample of 20 accessions of Arabidopsis thaliana. The distribution of allele frequencies,
BACKGROUND: Functional characteristics of the pharynx and upper esophagus, including aspiration episodes, were investigated in 14 awake volunteers during various levels of partial neuromuscular block. Pharyngeal function was evaluated using videoradiography and computerized pharyngeal manometry during contrast bolus swallowing. METHODS: Measurements of pharyngeal constrictor muscle function (contr
Purpose: To determine progression factors at the end of the Early Manifest Glaucoma Trial (EMGT) based on all EMGT patients and evaluate separately patients with higher and lower baseline intraocular pressure (IOP; median split). Design: Cohort of clinical trial participants. Participants: Patients with early open-angle glaucoma randomized to argon laser trabeculoplasty plus betaxolol (n = 129) or
The major function of the lower urinary tract is to store and periodically evacuate urine from the bladder. This requires coordination of the smooth muscles of the bladder and urethra, and of the striated muscles of the outflow region and pelvic floor by a complex neural control system. Lumbosacral afferent fibers (pelvic afferents), but also afferents in the hypogastric and pudendal nerves, are o
Solid immersion lenses (SILs) are optically transparent, truncated spheres, brought in contact with a sample to be imaged. The combination of a conventional optical microscope and a SIL results in a highly effective numerical aperture of the imaging system that can improve the resolution. In addition, when imaging high refractive index samples, such as semiconductors, the light collection efficien
