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Understanding factors influencing community resilience to disturbance is critical for mitigating harm at various scales, including harm from medication to gut microbiota and harm from human activity to global biodiversity, yet there is a lack of data from large-scale controlled experiments. Factors expected to boost resilience include prior exposure to the same disturbance and dispersal from undis
Purpose: To analyse the frequency and type of coexisting systemic disorders in children operated on for cataract in Sweden. Methods: Data were retrieved from the Swedish National Pediatric Cataract Register (PECARE) for children operated between January 1, 2007, and December 31, 2023 (n = 975), including follow-ups at age 1, 2, 5 and 10. Cataracts due to uveitis, trauma or radiation, and lens extr
Background: Parathyroidectomy is typically curative for primary hyperparathyroidism (PHPT) and may lead to health-related quality of life (HRQL) improvements. We aim to evaluate general and disease-specific HRQL changes in patients undergoing surgery for PHPT from their perspective. Methods: Patients completed three patient-reported outcome measure (PROM) surveys before and after surgery: (1) Worr
Atrial fibrillation (AF) is the most common heart rhythm abnormality and is a leading cause of heart failure and stroke. This large-scale meta-analysis of genome-wide association studies increased the power to detect single-nucleotide variant associations and found more than 350 AF-associated genetic loci. We identified candidate genes related to muscle contractility, cardiac muscle development an
The aim of this work is to redefine the concept of sensorimotor augmentation, extending it from wearable devices to supernumerary robotic upper limbs that are grounded and can be placed out of the physiological peripersonal space of the user. While the wearability of the supernumerary robotic limb (SRL) is not mandatory, the human-robot connection must be maintained through a wearable interface th
The complex structure of dairy operations requires the adoption of effective traceability mechanisms to ensure transparency, quality, and safety in a sustainable manner. This chapter explores the fundamental aspects of traceability, highlighting its ability to improve transparency, encourage consumer confidence, and ensure regulatory adherence in the dairy context. Integrating technological interv
Background SLE is a systemic autoimmune disease with a large number of common risk gene variants, but several rare gene variants can cause monogenic SLE. The relationship between common and rare variants in SLE is unclear. We therefore investigated the occurrence of rare deleterious variants in patients with childhood-onset SLE (cSLE) and adult-onset SLE (aSLE) and compared the frequency of these
Sub-minimum inhibiting concentrations (sub-MICs) of antibiotics frequently occur in natural environments owing to wide-spread antibiotic leakage by human action. Even though the concentrations are very low, these sub-MICs have recently been shown to alter bacterial populations by selecting for antibiotic resistance and increasing the rate of adaptive evolution. However, studies are lacking on how
Evolutionary prediction and control are increasingly interesting research topics that are expanding to new areas of application. Unravelling and anticipating successful adaptations to different selection pressures becomes crucial when steering rapidly evolving cancer or microbial populations towards a chosen target. Here we introduce and apply a rich theoretical framework of optimal control to und
Evolution has traditionally been a historical and descriptive science, and predicting future evolutionary processes has long been considered impossible. However, evolutionary predictions are increasingly being developed and used in medicine, agriculture, biotechnology and conservation biology. Evolutionary predictions may be used for different purposes, such as to prepare for the future, to try an
The natural world is under unprecedented and accelerating pressure. Much work on understanding resilience to local and global environmental change has, so far, focussed on ecosystems. However, understanding a system's behaviour requires knowledge of its component parts and their interactions. Here we call for increased efforts to understand 'biological resilience', or the processes that enable com
In response to increasing threats to biodiversity, conservation objectives have been set at national and international level, with the aim of halting biodiversity decline by reducing direct anthropogenic pressures on species. However, the potential effects of conservation policies derived from these objectives on common species remain rarely studied. Common species are often not the primary specie
The Big Butterfly Count reported its worst results in 14 years of monitoring UK species.
Butterflies have been systematically monitored in Europe for several decades using standard protocols that are now adopted in over 30 countries. Butterflies are ideal biological indicators: they are well-documented, measurable, sensitive to environmental change, occur in a wide range of habitat types, represent many other insects, and are popular with the public because of their beauty.Records froExecutive Summary Butterflies have been systematically monitored in Europe for several decades using standard protocols that are now adopted in over 30 countries. Butterflies are ideal biological indicators: they are well-documented, measurable, sensitive to environmental change, occur in a wide range of habitat types, represent many other insects, and are popular with the public because of their
Background: Growing concerns about food safety and quality practices require the dairy industry to sustain accountability and transparency. Knowing consumer perceptions and attitudes regarding traceability is critical for developing efficient market-driven approaches. Purpose of the Study: This empirical research explores consumer perceptions of product traceability within the dairy industry. It s
Introduction The Problematic Experience of Therapy Scale (PETS) identifies barriers to home-based exercise programs but has not been validated in hand therapy populations. This study aimed to translate the extended PETS into Swedish and evaluate its content and construct validity in patients undergoing early sensory relearning following peripheral nerve injury.Methods The PETS was translated into
Sensory traits shape animal lifestyles due to the central role they play in retrieving and processing environmental information. However, being some of the most energetically expensive tissues to build and maintain, ecological demands often modulate investment in these organs. Evidence that ecology shapes the evolution of sensory traits is plenty but is heavily biased towards vertebrates and has o
